Q6P5S8 (Q6P5S8_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
IGK@ protein EMBL AAH62704.1

Gene names

Name:

IGK@ EMBL AAH62704.1

Organism

Homo sapiens (Human) EMBL AAH62704.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	236 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Technical term	3D-structure PDB 2NY1 PDB 2NY3 PDB 2NY6 PDB 2NXY
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Binding site	120	1	Sucrose; via amide nitrogen PDB 2NY1 PDB 2NY3

Sequences

	Sequence		Length	Mass (Da)
	Q6P5S8 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 953E37BEB4FF5F27	FASTA	236	25,773
	10 20 30 40 50 60 METPAQLLFL LLLWLPDTTG EIVLTQSPGT LSFSPGERAT LSCRASQTVF SSHLAWYQQR 70 80 90 100 110 120 PGQAPRLLIY GASSRATGIP DRFSGSGSGT DFTLTITRLE PEDFAVYFCQ QYGTSPSLTF 130 140 150 160 170 180 GGGTRVEIKR TVAAPSVFIF PPSDEQLKSG TASVVCLLNN FYPREAKVQW KVDNALQSGN 190 200 210 220 230 SQESVTEQDS KDSTYSLSST LTLSKADYEK HKVYACEVTH QGLSSPVTKS FNRGEC

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M. , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J. Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Glandular pool- thyroid EMBL AAH62704.1.
[2]	"Structural definition of a conserved neutralization epitope on HIV-1 gp120." Zhou T., Xu L., Dey B., Hessell A.J., Van Ryk D., Xiang S.H., Yang X., Zhang M.Y., Zwick M.B., Arthos J., Burton D.R., Dimitrov D.S., Sodroski J., Wyatt R., Nabel G.J., Kwong P.D. Nature 445:732-737(2007) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.99 ANGSTROMS) OF 22-234 IN COMPLEX WITH SUCROSE.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

BC062704 mRNA. Translation: AAH62704.1.

IPI

IPI00784865.

UniGene

Hs.449609.
Hs.606838.
Hs.719895.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2NXY	X-ray	2.00	C	22-234	[»]
2NY1	X-ray	1.99	C	22-234	[»]
2NY3	X-ray	2.00	C	22-234	[»]
2NY6	X-ray	2.80	C	22-234	[»]

ProteinModelPortal

Q6P5S8.

SMR

Q6P5S8. Positions 21-236.

ModBase

Search...

Protein-protein interaction databases

STRING

Q6P5S8.

PTM databases

PhosphoSite

Q6P5S8.

Proteomic databases

PeptideAtlas

Q6P5S8.

PRIDE

Q6P5S8.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Phylogenomic databases

HOGENOM

HOG000059537.

HOVERGEN

HBG018013.

Family and domain databases

Gene3D

2.60.40.10. 2 hits.

InterPro

IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
IPR013106. Ig_V-set.
IPR003596. Ig_V-set_subgr.
[Graphical view]

Pfam

PF07654. C1-set. 1 hit.
PF07686. V-set. 1 hit.
[Graphical view]

SMART

SM00407. IGc1. 1 hit.
SM00406. IGv. 1 hit.
[Graphical view]

PROSITE

PS50835. IG_LIKE. 2 hits.
PS00290. IG_MHC. 1 hit.
[Graphical view]

ProtoNet

Search...

Other

EvolutionaryTrace

Q6P5S8.

Entry information

Entry name

Q6P5S8_HUMAN

Accession

Primary (citable) accession number: Q6P5S8

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	March 6, 2013
This is version 70 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.