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Protein

60S ribosomal protein L19

Gene

rpl19

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • hemopoiesis Source: ZFIN
  • translation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-DRE-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-DRE-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-DRE-6791226. Major pathway of rRNA processing in the nucleolus.
R-DRE-72689. Formation of a pool of free 40S subunits.
R-DRE-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-DRE-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-DRE-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L19
Gene namesi
Name:rpl19
ORF Names:zgc:77733
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 3

Organism-specific databases

ZFINiZDB-GENE-040426-2290. rpl19.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 19619660S ribosomal protein L19PRO_0000131173Add
BLAST

Proteomic databases

PaxDbiQ6P5L3.
PRIDEiQ6P5L3.

Expressioni

Gene expression databases

BgeeiQ6P5L3.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000105649.

Structurei

3D structure databases

ProteinModelPortaliQ6P5L3.
SMRiQ6P5L3. Positions 9-191.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L19e family.Curated

Phylogenomic databases

eggNOGiKOG1696. Eukaryota.
COG2147. LUCA.
GeneTreeiENSGT00390000012628.
HOGENOMiHOG000231277.
HOVERGENiHBG056059.
InParanoidiQ6P5L3.
KOiK02885.
OMAiEHIIQAK.
OrthoDBiEOG75B86V.
PhylomeDBiQ6P5L3.
TreeFamiTF313598.

Family and domain databases

Gene3Di1.10.1200.60. 1 hit.
1.10.1650.10. 1 hit.
HAMAPiMF_01475. Ribosomal_L19e.
InterProiIPR027547. Ribosomal_L19/L19e.
IPR023638. Ribosomal_L19/L19e_CS.
IPR000196. Ribosomal_L19/L19e_dom.
IPR015972. Ribosomal_L19/L19e_dom1.
IPR015974. Ribosomal_L19/L19e_dom3.
[Graphical view]
PfamiPF01280. Ribosomal_L19e. 1 hit.
[Graphical view]
SMARTiSM01416. Ribosomal_L19e. 1 hit.
[Graphical view]
SUPFAMiSSF48140. SSF48140. 1 hit.
PROSITEiPS00526. RIBOSOMAL_L19E. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6P5L3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSMLRLQKRL ASSVLRCGKK KVWLDPNETN EIANANSRQQ IRKLVKDGLI
60 70 80 90 100
IKKPVTVHSR ARCRKNTLAR RKGRHMGVGK RKGTANARMP EKLCWMRRMR
110 120 130 140 150
ILRRLLRRYR EAKKIDRHMY HSLYLRAKGN VFKNKRILME HIHKLKADKA
160 170 180 190
RKKLLADQAE ARRTKTREAR KRREERQQAK KEEIIKTLSK EDETKK
Length:196
Mass (Da):23,453
Last modified:July 5, 2004 - v1
Checksum:i8FB064826ACE2DF0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY648758 mRNA. Translation: AAT68076.1.
BC062844 mRNA. Translation: AAH62844.1.
RefSeqiNP_998373.1. NM_213208.1.
UniGeneiDr.31918.

Genome annotation databases

EnsembliENSDART00000121728; ENSDARP00000105649; ENSDARG00000013307.
GeneIDi406489.
KEGGidre:406489.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY648758 mRNA. Translation: AAT68076.1.
BC062844 mRNA. Translation: AAH62844.1.
RefSeqiNP_998373.1. NM_213208.1.
UniGeneiDr.31918.

3D structure databases

ProteinModelPortaliQ6P5L3.
SMRiQ6P5L3. Positions 9-191.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000105649.

Proteomic databases

PaxDbiQ6P5L3.
PRIDEiQ6P5L3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000121728; ENSDARP00000105649; ENSDARG00000013307.
GeneIDi406489.
KEGGidre:406489.

Organism-specific databases

CTDi6143.
ZFINiZDB-GENE-040426-2290. rpl19.

Phylogenomic databases

eggNOGiKOG1696. Eukaryota.
COG2147. LUCA.
GeneTreeiENSGT00390000012628.
HOGENOMiHOG000231277.
HOVERGENiHBG056059.
InParanoidiQ6P5L3.
KOiK02885.
OMAiEHIIQAK.
OrthoDBiEOG75B86V.
PhylomeDBiQ6P5L3.
TreeFamiTF313598.

Enzyme and pathway databases

ReactomeiR-DRE-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-DRE-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-DRE-6791226. Major pathway of rRNA processing in the nucleolus.
R-DRE-72689. Formation of a pool of free 40S subunits.
R-DRE-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-DRE-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-DRE-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Miscellaneous databases

PROiQ6P5L3.

Gene expression databases

BgeeiQ6P5L3.

Family and domain databases

Gene3Di1.10.1200.60. 1 hit.
1.10.1650.10. 1 hit.
HAMAPiMF_01475. Ribosomal_L19e.
InterProiIPR027547. Ribosomal_L19/L19e.
IPR023638. Ribosomal_L19/L19e_CS.
IPR000196. Ribosomal_L19/L19e_dom.
IPR015972. Ribosomal_L19/L19e_dom1.
IPR015974. Ribosomal_L19/L19e_dom3.
[Graphical view]
PfamiPF01280. Ribosomal_L19e. 1 hit.
[Graphical view]
SMARTiSM01416. Ribosomal_L19e. 1 hit.
[Graphical view]
SUPFAMiSSF48140. SSF48140. 1 hit.
PROSITEiPS00526. RIBOSOMAL_L19E. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
  2. NIH - Zebrafish Gene Collection (ZGC) project
    Submitted (NOV-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].

Entry informationi

Entry nameiRL19_DANRE
AccessioniPrimary (citable) accession number: Q6P5L3
Secondary accession number(s): Q6DRK1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 16, 2004
Last sequence update: July 5, 2004
Last modified: June 8, 2016
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.