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Protein
Submitted name:

Mtmr2 protein

Gene

Mtmr2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Mtmr2 proteinImported
Submitted name:
Myotubularin-related protein 2Imported
Gene namesi
Name:Mtmr2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 9

Organism-specific databases

MGIiMGI:1924366. Mtmr2.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Expressioni

Gene expression databases

BgeeiENSMUSG00000031918.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000034396.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini133 – 508Myotubularin phosphataseInterPro annotationAdd BLAST376
Domaini314 – 361TYR_PHOSPHATASE_2InterPro annotationAdd BLAST48

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili525 – 552Sequence analysisAdd BLAST28

Sequence similaritiesi

Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.SAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG1089. Eukaryota.
ENOG410XPTU. LUCA.
GeneTreeiENSGT00760000118832.
HOVERGENiHBG000220.
KOiK18081.

Family and domain databases

Gene3Di2.30.29.30. 1 hit.
3.90.190.10. 1 hit.
InterProiIPR004182. GRAM.
IPR010569. Myotubularin-like_Pase_dom.
IPR030564. Myotubularin_fam.
IPR011993. PH_dom-like.
IPR029021. Prot-tyrosine_phosphatase-like.
IPR016130. Tyr_Pase_AS.
IPR003595. Tyr_Pase_cat.
IPR000387. TYR_PHOSPHATASE_dom.
[Graphical view]
PANTHERiPTHR10807. PTHR10807. 1 hit.
PfamiPF02893. GRAM. 1 hit.
PF06602. Myotub-related. 1 hit.
[Graphical view]
SMARTiSM00568. GRAM. 1 hit.
SM00404. PTPc_motif. 1 hit.
[Graphical view]
SUPFAMiSSF50729. SSF50729. 1 hit.
SSF52799. SSF52799. 1 hit.
PROSITEiPS51339. PPASE_MYOTUBULARIN. 1 hit.
PS00383. TYR_PHOSPHATASE_1. 1 hit.
PS50056. TYR_PHOSPHATASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6P572-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEEPALLPGE NIKDMAKDVT YICPFTGAVR GTLTVTSYRL YFKSMERDPP
60 70 80 90 100
FVLDASLGVI SRVEKIGGAS SRGENSYGLE TVCKDIRNLR FAHKPEGRTR
110 120 130 140 150
RSIFENLMKY AFPVSNGLPL FAFEYKEVFP ENGWKLYDPL LEYRRQGIPN
160 170 180 190 200
ESWRITKINE RYELCDTYPA LLVVPANIPD EELKRVASFR SRGRIPVLSW
210 220 230 240 250
IHPESQATVT RCSQPMVGVS GKRSKEDEKY LQAIMDSNAQ SHKIFIFDAR
260 270 280 290 300
PSVNAVANKA KGGGYESEDA YQNAELVFLD IHNIHVMRES LRKLKEIVYP
310 320 330 340 350
TIEETHWLSN LESTHWLEHI KLILAGALRI ADKVESGKTS VVVHCSDGWD
360 370 380 390 400
RTAQLTSLAM LMLDGYYRTI RGFEVLVEKE WLSFGHRFQL RVGHGDKNHA
410 420 430 440 450
DADRSPVFLQ FIDCVWQMTR QFPTAFEFNE YFLITILDHL YSCLFGTFLC
460 470 480 490 500
NSEQQRGKEN LPKKTVSLWS YINSQLEDFT NPLYGSYSNH VLYPVASMRH
510 520 530 540 550
LELWVGYYIR WNPRMKPQEP IHSRYKELLA KRAELQRKVE ELQREISNRS
560 570
TSSSERASSP AQCVTPVQTV V
Length:571
Mass (Da):65,768
Last modified:July 5, 2004 - v1
Checksum:i3A0872B069D5927A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CT010488 Genomic DNA. No translation available.
BC063050 mRNA. Translation: AAH63050.1.
RefSeqiNP_076347.3. NM_023858.3.
XP_006510746.1. XM_006510683.2.
XP_017169181.1. XM_017313692.1.
XP_017169182.1. XM_017313693.1.
UniGeneiMm.210405.

Genome annotation databases

EnsembliENSMUST00000155679; ENSMUSP00000115906; ENSMUSG00000031918.
GeneIDi77116.
KEGGimmu:77116.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CT010488 Genomic DNA. No translation available.
BC063050 mRNA. Translation: AAH63050.1.
RefSeqiNP_076347.3. NM_023858.3.
XP_006510746.1. XM_006510683.2.
XP_017169181.1. XM_017313692.1.
XP_017169182.1. XM_017313693.1.
UniGeneiMm.210405.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000034396.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000155679; ENSMUSP00000115906; ENSMUSG00000031918.
GeneIDi77116.
KEGGimmu:77116.

Organism-specific databases

CTDi8898.
MGIiMGI:1924366. Mtmr2.

Phylogenomic databases

eggNOGiKOG1089. Eukaryota.
ENOG410XPTU. LUCA.
GeneTreeiENSGT00760000118832.
HOVERGENiHBG000220.
KOiK18081.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000031918.

Family and domain databases

Gene3Di2.30.29.30. 1 hit.
3.90.190.10. 1 hit.
InterProiIPR004182. GRAM.
IPR010569. Myotubularin-like_Pase_dom.
IPR030564. Myotubularin_fam.
IPR011993. PH_dom-like.
IPR029021. Prot-tyrosine_phosphatase-like.
IPR016130. Tyr_Pase_AS.
IPR003595. Tyr_Pase_cat.
IPR000387. TYR_PHOSPHATASE_dom.
[Graphical view]
PANTHERiPTHR10807. PTHR10807. 1 hit.
PfamiPF02893. GRAM. 1 hit.
PF06602. Myotub-related. 1 hit.
[Graphical view]
SMARTiSM00568. GRAM. 1 hit.
SM00404. PTPc_motif. 1 hit.
[Graphical view]
SUPFAMiSSF50729. SSF50729. 1 hit.
SSF52799. SSF52799. 1 hit.
PROSITEiPS51339. PPASE_MYOTUBULARIN. 1 hit.
PS00383. TYR_PHOSPHATASE_1. 1 hit.
PS50056. TYR_PHOSPHATASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ6P572_MOUSE
AccessioniPrimary (citable) accession number: Q6P572
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: November 30, 2016
This is version 102 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.