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Protein
Submitted name:

BCL2-associated X protein

Gene

bax

Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-XTR-114294. Activation, translocation and oligomerization of BAX.
R-XTR-6804114. TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest.

Names & Taxonomyi

Protein namesi
Submitted name:
BCL2-associated X proteinImported
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:baxImported
ORF Names:TGas091l04.1-001Imported
OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)Imported
Taxonomic identifieri8364 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana
Proteomesi
  • UP000008143 Componenti: Unassembled WGS sequence

Organism-specific databases

XenbaseiXB-GENE-486067. bax.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei200 – 21819HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSXETG00000023523.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi8364.ENSXETP00000050759.

Structurei

3D structure databases

SMRiQ6P4Y4. Positions 36-219.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IWQJ. Eukaryota.
ENOG4112738. LUCA.
GeneTreeiENSGT00730000111112.
HOGENOMiHOG000095178.
HOVERGENiHBG003606.
KOiK02159.
OMAiNMINDSA.
OrthoDBiEOG091G0YWR.
TreeFamiTF315834.

Family and domain databases

InterProiIPR026304. BAX.
IPR002475. Bcl2-like.
IPR026298. Blc2_fam.
[Graphical view]
PANTHERiPTHR11256. PTHR11256. 1 hit.
PTHR11256:SF44. PTHR11256:SF44. 1 hit.
PfamiPF00452. Bcl-2. 1 hit.
[Graphical view]
PRINTSiPR01862. BCL2FAMILY.
PROSITEiPS50062. BCL2_FAMILY. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6P4Y4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATHGAGGDY PGEDKEKNQG EGGAAGGPSL GAAGDRSGTG VSTEQILETG
60 70 80 90 100
ELLLNGFISD RLQNNPDVAG ARALFPGSTQ HSDPSIKRLS ECLRKIGDEL
110 120 130 140 150
DANIELQRRI ECVPCNSPKQ VFFHVAKELF ADGVFNWGRV VALFYFACKL
160 170 180 190 200
VVKALCTKVP EMIRTIINWT MEYLREYVVQ WIRDQGGWEG MLSYFGTPTW
210 220
QTVGVFLAGV LTATIAIWKM S
Length:221
Mass (Da):24,163
Last modified:July 5, 2004 - v1
Checksum:i87E367DB1614CEEB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAMC01122515 Genomic DNA. No translation available.
BC063201 mRNA. Translation: AAH63201.1.
CR855728 mRNA. Translation: CAJ81524.1.
RefSeqiNP_989185.1. NM_203854.1.
UniGeneiStr.6535.

Genome annotation databases

EnsembliENSXETT00000050759; ENSXETP00000050759; ENSXETG00000023523.
GeneIDi394793.
KEGGixtr:394793.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAMC01122515 Genomic DNA. No translation available.
BC063201 mRNA. Translation: AAH63201.1.
CR855728 mRNA. Translation: CAJ81524.1.
RefSeqiNP_989185.1. NM_203854.1.
UniGeneiStr.6535.

3D structure databases

SMRiQ6P4Y4. Positions 36-219.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi8364.ENSXETP00000050759.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSXETT00000050759; ENSXETP00000050759; ENSXETG00000023523.
GeneIDi394793.
KEGGixtr:394793.

Organism-specific databases

CTDi581.
XenbaseiXB-GENE-486067. bax.

Phylogenomic databases

eggNOGiENOG410IWQJ. Eukaryota.
ENOG4112738. LUCA.
GeneTreeiENSGT00730000111112.
HOGENOMiHOG000095178.
HOVERGENiHBG003606.
KOiK02159.
OMAiNMINDSA.
OrthoDBiEOG091G0YWR.
TreeFamiTF315834.

Enzyme and pathway databases

ReactomeiR-XTR-114294. Activation, translocation and oligomerization of BAX.
R-XTR-6804114. TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest.

Gene expression databases

BgeeiENSXETG00000023523.

Family and domain databases

InterProiIPR026304. BAX.
IPR002475. Bcl2-like.
IPR026298. Blc2_fam.
[Graphical view]
PANTHERiPTHR11256. PTHR11256. 1 hit.
PTHR11256:SF44. PTHR11256:SF44. 1 hit.
PfamiPF00452. Bcl-2. 1 hit.
[Graphical view]
PRINTSiPR01862. BCL2FAMILY.
PROSITEiPS50062. BCL2_FAMILY. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ6P4Y4_XENTR
AccessioniPrimary (citable) accession number: Q6P4Y4
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: September 7, 2016
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.