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Protein
Submitted name:

Ptpro protein

Gene

Ptpro

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei493Phosphocysteine intermediatePROSITE-ProRule annotation1

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Ptpro proteinImported
Gene namesi
Name:PtproImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1097152. Ptpro.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei177 – 201HelicalSequence analysisAdd BLAST25
Transmembranei237 – 258HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ6P4T4.

Structurei

3D structure databases

ProteinModelPortaliQ6P4T4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 81Fibronectin type-IIIInterPro annotationAdd BLAST81
Domaini82 – 174Fibronectin type-IIIInterPro annotationAdd BLAST93
Domaini295 – 552Tyrosine-protein phosphataseInterPro annotationAdd BLAST258
Domaini469 – 543TYR_PHOSPHATASE_2InterPro annotationAdd BLAST75

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG0791. Eukaryota.
COG5599. LUCA.
HOVERGENiHBG053969.
PhylomeDBiQ6P4T4.

Family and domain databases

CDDicd00063. FN3. 1 hit.
Gene3Di2.60.40.10. 2 hits.
3.90.190.10. 1 hit.
InterProiView protein in InterPro
IPR003961. FN3_dom.
IPR036116. FN3_sf.
IPR013783. Ig-like_fold.
IPR029021. Prot-tyrosine_phosphatase-like.
IPR000242. PTPase_domain.
IPR016130. Tyr_Pase_AS.
IPR003595. Tyr_Pase_cat.
IPR000387. TYR_PHOSPHATASE_dom.
PfamiView protein in Pfam
PF00041. fn3. 1 hit.
PF00102. Y_phosphatase. 1 hit.
PRINTSiPR00700. PRTYPHPHTASE.
SMARTiView protein in SMART
SM00060. FN3. 1 hit.
SM00194. PTPc. 1 hit.
SM00404. PTPc_motif. 1 hit.
SUPFAMiSSF49265. SSF49265. 1 hit.
SSF52799. SSF52799. 1 hit.
PROSITEiView protein in PROSITE
PS50853. FN3. 2 hits.
PS00383. TYR_PHOSPHATASE_1. 1 hit.
PS50056. TYR_PHOSPHATASE_2. 1 hit.
PS50055. TYR_PHOSPHATASE_PTP. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q6P4T4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
NSLLYISWTY GDATTDLSHS RMLHWMVVAE GRKKIKKSVT RNVMTAILSL
60 70 80 90 100
PPGDIYNLSV TACTERGSNT SLPRLVKLEP APPKSLFAVN KTQTSVTLLW
110 120 130 140 150
VEEGVADFFE VFCQQLGSGH NGKLQEPVAV SSHVVTISSL LPATAYNCSV
160 170 180 190 200
TSFSHDTPSV PTFIAVSTMV TEVNPNVVVI SVLAILSTLL IGLLLVTLVI
210 220 230 240 250
LRKKHLQMAR ECGAGTFVNF ASLEREGKLP YSWRRSVFAL LTLLPSCLWT
260 270 280 290 300
DYLLAFYINP WSKNGLKKRK LTNPVQLDDF DSYIKDMAKD SDYKFSLQFE
310 320 330 340 350
ELKLIGLDIP HFAADLPLNR CKNRYTNILP YDFSRVRLVS MNEEEGADYI
360 370 380 390 400
NANYIPGYNS PQEYIATQGP LPETRNDFWK MVLQQKSHII VMLTQCNEKR
410 420 430 440 450
RVKCDHYWPF TEEPIAYGDI TVEMVSEEEE EDWASRHFRI NYADEAQDVM
460 470 480 490 500
HFNYTAWPDH GVPPANAAES ILQFVFTVRQ QAAKSKGPMI IHCSAGVGRT
510 520 530 540 550
GTFIALDRLL QHIRDHEFVD ILGLVSEMRS YRMSMVQTEE QYIFIHQCVQ
560 570
LMWLRKKQQF CISDVIYENV SKS
Length:573
Mass (Da):65,186
Last modified:July 5, 2004 - v1
Checksum:i8AA55B843CCB6D95
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC063258 mRNA. Translation: AAH63258.1.
UniGeneiMm.186361.
Mm.491536.

Similar proteinsi

Entry informationi

Entry nameiQ6P4T4_MOUSE
AccessioniPrimary (citable) accession number: Q6P4T4
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: October 25, 2017
This is version 96 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)