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Q6P4T4

- Q6P4T4_MOUSE

UniProt

Q6P4T4 - Q6P4T4_MOUSE

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Protein
Submitted name:

Ptpro protein

Gene

Ptpro

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. protein tyrosine phosphatase activity Source: InterPro

GO - Biological processi

  1. glomerulus development Source: Ensembl
  2. monocyte chemotaxis Source: Ensembl
  3. negative regulation of glomerular filtration Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

HydrolaseUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Ptpro proteinImported
Gene namesi
Name:PtproImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1097152. Ptpro.

Subcellular locationi

GO - Cellular componenti

  1. extracellular vesicular exosome Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiQ6P4T4.
ExpressionAtlasiQ6P4T4. baseline and differential.
GenevestigatoriQ6P4T4.

Structurei

3D structure databases

ProteinModelPortaliQ6P4T4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG053969.
PhylomeDBiQ6P4T4.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
3.90.190.10. 1 hit.
InterProiIPR003961. Fibronectin_type3.
IPR013783. Ig-like_fold.
IPR029021. Prot-tyrosine_phosphatase-like.
IPR000387. Tyr/Dual-sp_Pase.
IPR016130. Tyr_Pase_AS.
IPR000242. Tyr_Pase_rcpt/non-rcpt.
[Graphical view]
PfamiPF00041. fn3. 1 hit.
PF00102. Y_phosphatase. 1 hit.
[Graphical view]
PRINTSiPR00700. PRTYPHPHTASE.
SMARTiSM00060. FN3. 1 hit.
SM00194. PTPc. 1 hit.
[Graphical view]
SUPFAMiSSF49265. SSF49265. 1 hit.
SSF52799. SSF52799. 1 hit.
PROSITEiPS50853. FN3. 1 hit.
PS00383. TYR_PHOSPHATASE_1. 1 hit.
PS50056. TYR_PHOSPHATASE_2. 1 hit.
PS50055. TYR_PHOSPHATASE_PTP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q6P4T4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
NSLLYISWTY GDATTDLSHS RMLHWMVVAE GRKKIKKSVT RNVMTAILSL
60 70 80 90 100
PPGDIYNLSV TACTERGSNT SLPRLVKLEP APPKSLFAVN KTQTSVTLLW
110 120 130 140 150
VEEGVADFFE VFCQQLGSGH NGKLQEPVAV SSHVVTISSL LPATAYNCSV
160 170 180 190 200
TSFSHDTPSV PTFIAVSTMV TEVNPNVVVI SVLAILSTLL IGLLLVTLVI
210 220 230 240 250
LRKKHLQMAR ECGAGTFVNF ASLEREGKLP YSWRRSVFAL LTLLPSCLWT
260 270 280 290 300
DYLLAFYINP WSKNGLKKRK LTNPVQLDDF DSYIKDMAKD SDYKFSLQFE
310 320 330 340 350
ELKLIGLDIP HFAADLPLNR CKNRYTNILP YDFSRVRLVS MNEEEGADYI
360 370 380 390 400
NANYIPGYNS PQEYIATQGP LPETRNDFWK MVLQQKSHII VMLTQCNEKR
410 420 430 440 450
RVKCDHYWPF TEEPIAYGDI TVEMVSEEEE EDWASRHFRI NYADEAQDVM
460 470 480 490 500
HFNYTAWPDH GVPPANAAES ILQFVFTVRQ QAAKSKGPMI IHCSAGVGRT
510 520 530 540 550
GTFIALDRLL QHIRDHEFVD ILGLVSEMRS YRMSMVQTEE QYIFIHQCVQ
560 570
LMWLRKKQQF CISDVIYENV SKS
Length:573
Mass (Da):65,186
Last modified:July 5, 2004 - v1
Checksum:i8AA55B843CCB6D95
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC063258 mRNA. Translation: AAH63258.1.
UniGeneiMm.186361.
Mm.491536.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC063258 mRNA. Translation: AAH63258.1 .
UniGenei Mm.186361.
Mm.491536.

3D structure databases

ProteinModelPortali Q6P4T4.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

MGIi MGI:1097152. Ptpro.

Phylogenomic databases

HOVERGENi HBG053969.
PhylomeDBi Q6P4T4.

Miscellaneous databases

SOURCEi Search...

Gene expression databases

Bgeei Q6P4T4.
ExpressionAtlasi Q6P4T4. baseline and differential.
Genevestigatori Q6P4T4.

Family and domain databases

Gene3Di 2.60.40.10. 1 hit.
3.90.190.10. 1 hit.
InterProi IPR003961. Fibronectin_type3.
IPR013783. Ig-like_fold.
IPR029021. Prot-tyrosine_phosphatase-like.
IPR000387. Tyr/Dual-sp_Pase.
IPR016130. Tyr_Pase_AS.
IPR000242. Tyr_Pase_rcpt/non-rcpt.
[Graphical view ]
Pfami PF00041. fn3. 1 hit.
PF00102. Y_phosphatase. 1 hit.
[Graphical view ]
PRINTSi PR00700. PRTYPHPHTASE.
SMARTi SM00060. FN3. 1 hit.
SM00194. PTPc. 1 hit.
[Graphical view ]
SUPFAMi SSF49265. SSF49265. 1 hit.
SSF52799. SSF52799. 1 hit.
PROSITEi PS50853. FN3. 1 hit.
PS00383. TYR_PHOSPHATASE_1. 1 hit.
PS50056. TYR_PHOSPHATASE_2. 1 hit.
PS50055. TYR_PHOSPHATASE_PTP. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6Imported.
    Tissue: BrainImported.

Entry informationi

Entry nameiQ6P4T4_MOUSE
AccessioniPrimary (citable) accession number: Q6P4T4
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: October 29, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)