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Protein
Submitted name:

Ptpro protein

Gene

Ptpro

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei493Phosphocysteine intermediatePROSITE-ProRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolasePROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Ptpro proteinImported
Gene namesi
Name:PtproImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1097152 Ptpro

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei177 – 201HelicalSequence analysisAdd BLAST25
Transmembranei237 – 258HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

Structurei

3D structure databases

ProteinModelPortaliQ6P4T4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 81Fibronectin type-IIIInterPro annotationAdd BLAST81
Domaini82 – 174Fibronectin type-IIIInterPro annotationAdd BLAST93
Domaini295 – 552Tyrosine-protein phosphataseInterPro annotationAdd BLAST258
Domaini469 – 543TYR_PHOSPHATASE_2InterPro annotationAdd BLAST75

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG0791 Eukaryota
COG5599 LUCA
HOVERGENiHBG053969
PhylomeDBiQ6P4T4

Family and domain databases

CDDicd00063 FN3, 1 hit
Gene3Di2.60.40.10, 1 hit
3.90.190.10, 1 hit
InterProiView protein in InterPro
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR013783 Ig-like_fold
IPR029021 Prot-tyrosine_phosphatase-like
IPR000242 PTPase_domain
IPR016130 Tyr_Pase_AS
IPR003595 Tyr_Pase_cat
IPR000387 TYR_PHOSPHATASE_dom
PfamiView protein in Pfam
PF00041 fn3, 1 hit
PF00102 Y_phosphatase, 1 hit
PRINTSiPR00700 PRTYPHPHTASE
SMARTiView protein in SMART
SM00060 FN3, 1 hit
SM00194 PTPc, 1 hit
SM00404 PTPc_motif, 1 hit
SUPFAMiSSF49265 SSF49265, 1 hit
SSF52799 SSF52799, 1 hit
PROSITEiView protein in PROSITE
PS50853 FN3, 2 hits
PS00383 TYR_PHOSPHATASE_1, 1 hit
PS50056 TYR_PHOSPHATASE_2, 1 hit
PS50055 TYR_PHOSPHATASE_PTP, 1 hit

Sequencei

Sequence statusi: Fragment.

Q6P4T4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
NSLLYISWTY GDATTDLSHS RMLHWMVVAE GRKKIKKSVT RNVMTAILSL
60 70 80 90 100
PPGDIYNLSV TACTERGSNT SLPRLVKLEP APPKSLFAVN KTQTSVTLLW
110 120 130 140 150
VEEGVADFFE VFCQQLGSGH NGKLQEPVAV SSHVVTISSL LPATAYNCSV
160 170 180 190 200
TSFSHDTPSV PTFIAVSTMV TEVNPNVVVI SVLAILSTLL IGLLLVTLVI
210 220 230 240 250
LRKKHLQMAR ECGAGTFVNF ASLEREGKLP YSWRRSVFAL LTLLPSCLWT
260 270 280 290 300
DYLLAFYINP WSKNGLKKRK LTNPVQLDDF DSYIKDMAKD SDYKFSLQFE
310 320 330 340 350
ELKLIGLDIP HFAADLPLNR CKNRYTNILP YDFSRVRLVS MNEEEGADYI
360 370 380 390 400
NANYIPGYNS PQEYIATQGP LPETRNDFWK MVLQQKSHII VMLTQCNEKR
410 420 430 440 450
RVKCDHYWPF TEEPIAYGDI TVEMVSEEEE EDWASRHFRI NYADEAQDVM
460 470 480 490 500
HFNYTAWPDH GVPPANAAES ILQFVFTVRQ QAAKSKGPMI IHCSAGVGRT
510 520 530 540 550
GTFIALDRLL QHIRDHEFVD ILGLVSEMRS YRMSMVQTEE QYIFIHQCVQ
560 570
LMWLRKKQQF CISDVIYENV SKS
Length:573
Mass (Da):65,186
Last modified:July 5, 2004 - v1
Checksum:i8AA55B843CCB6D95
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC063258 mRNA Translation: AAH63258.1
UniGeneiMm.186361
Mm.491536

Similar proteinsi

Entry informationi

Entry nameiQ6P4T4_MOUSE
AccessioniPrimary (citable) accession number: Q6P4T4
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: May 23, 2018
This is version 99 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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