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Protein
Submitted name:

Ptpro protein

Gene

Ptpro

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Ptpro proteinImported
Gene namesi
Name:PtproImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1097152. Ptpro.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei177 – 201HelicalSequence analysisAdd BLAST25
Transmembranei237 – 258HelicalSequence analysisAdd BLAST22

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ6P4T4.

Expressioni

Gene expression databases

BgeeiENSMUSG00000030223.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000076364.

Structurei

3D structure databases

ProteinModelPortaliQ6P4T4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 81Fibronectin type-IIIInterPro annotationAdd BLAST81
Domaini82 – 174Fibronectin type-IIIInterPro annotationAdd BLAST93
Domaini295 – 552Tyrosine-protein phosphataseInterPro annotationAdd BLAST258
Domaini469 – 543TYR_PHOSPHATASE_2InterPro annotationAdd BLAST75

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG0791. Eukaryota.
COG5599. LUCA.
HOVERGENiHBG053969.
PhylomeDBiQ6P4T4.

Family and domain databases

CDDicd00063. FN3. 1 hit.
Gene3Di2.60.40.10. 1 hit.
3.90.190.10. 1 hit.
InterProiIPR003961. FN3_dom.
IPR013783. Ig-like_fold.
IPR029021. Prot-tyrosine_phosphatase-like.
IPR000242. PTPase_domain.
IPR016130. Tyr_Pase_AS.
IPR003595. Tyr_Pase_cat.
IPR000387. TYR_PHOSPHATASE_dom.
[Graphical view]
PfamiPF00041. fn3. 1 hit.
PF00102. Y_phosphatase. 1 hit.
[Graphical view]
PRINTSiPR00700. PRTYPHPHTASE.
SMARTiSM00060. FN3. 1 hit.
SM00194. PTPc. 1 hit.
SM00404. PTPc_motif. 1 hit.
[Graphical view]
SUPFAMiSSF49265. SSF49265. 1 hit.
SSF52799. SSF52799. 1 hit.
PROSITEiPS50853. FN3. 2 hits.
PS00383. TYR_PHOSPHATASE_1. 1 hit.
PS50056. TYR_PHOSPHATASE_2. 1 hit.
PS50055. TYR_PHOSPHATASE_PTP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q6P4T4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
NSLLYISWTY GDATTDLSHS RMLHWMVVAE GRKKIKKSVT RNVMTAILSL
60 70 80 90 100
PPGDIYNLSV TACTERGSNT SLPRLVKLEP APPKSLFAVN KTQTSVTLLW
110 120 130 140 150
VEEGVADFFE VFCQQLGSGH NGKLQEPVAV SSHVVTISSL LPATAYNCSV
160 170 180 190 200
TSFSHDTPSV PTFIAVSTMV TEVNPNVVVI SVLAILSTLL IGLLLVTLVI
210 220 230 240 250
LRKKHLQMAR ECGAGTFVNF ASLEREGKLP YSWRRSVFAL LTLLPSCLWT
260 270 280 290 300
DYLLAFYINP WSKNGLKKRK LTNPVQLDDF DSYIKDMAKD SDYKFSLQFE
310 320 330 340 350
ELKLIGLDIP HFAADLPLNR CKNRYTNILP YDFSRVRLVS MNEEEGADYI
360 370 380 390 400
NANYIPGYNS PQEYIATQGP LPETRNDFWK MVLQQKSHII VMLTQCNEKR
410 420 430 440 450
RVKCDHYWPF TEEPIAYGDI TVEMVSEEEE EDWASRHFRI NYADEAQDVM
460 470 480 490 500
HFNYTAWPDH GVPPANAAES ILQFVFTVRQ QAAKSKGPMI IHCSAGVGRT
510 520 530 540 550
GTFIALDRLL QHIRDHEFVD ILGLVSEMRS YRMSMVQTEE QYIFIHQCVQ
560 570
LMWLRKKQQF CISDVIYENV SKS
Length:573
Mass (Da):65,186
Last modified:July 5, 2004 - v1
Checksum:i8AA55B843CCB6D95
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC063258 mRNA. Translation: AAH63258.1.
UniGeneiMm.186361.
Mm.491536.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC063258 mRNA. Translation: AAH63258.1.
UniGeneiMm.186361.
Mm.491536.

3D structure databases

ProteinModelPortaliQ6P4T4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000076364.

Proteomic databases

PaxDbiQ6P4T4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MGIiMGI:1097152. Ptpro.

Phylogenomic databases

eggNOGiKOG0791. Eukaryota.
COG5599. LUCA.
HOVERGENiHBG053969.
PhylomeDBiQ6P4T4.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000030223.

Family and domain databases

CDDicd00063. FN3. 1 hit.
Gene3Di2.60.40.10. 1 hit.
3.90.190.10. 1 hit.
InterProiIPR003961. FN3_dom.
IPR013783. Ig-like_fold.
IPR029021. Prot-tyrosine_phosphatase-like.
IPR000242. PTPase_domain.
IPR016130. Tyr_Pase_AS.
IPR003595. Tyr_Pase_cat.
IPR000387. TYR_PHOSPHATASE_dom.
[Graphical view]
PfamiPF00041. fn3. 1 hit.
PF00102. Y_phosphatase. 1 hit.
[Graphical view]
PRINTSiPR00700. PRTYPHPHTASE.
SMARTiSM00060. FN3. 1 hit.
SM00194. PTPc. 1 hit.
SM00404. PTPc_motif. 1 hit.
[Graphical view]
SUPFAMiSSF49265. SSF49265. 1 hit.
SSF52799. SSF52799. 1 hit.
PROSITEiPS50853. FN3. 2 hits.
PS00383. TYR_PHOSPHATASE_1. 1 hit.
PS50056. TYR_PHOSPHATASE_2. 1 hit.
PS50055. TYR_PHOSPHATASE_PTP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ6P4T4_MOUSE
AccessioniPrimary (citable) accession number: Q6P4T4
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: November 30, 2016
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.