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Q6P4T4

- Q6P4T4_MOUSE

UniProt

Q6P4T4 - Q6P4T4_MOUSE

Protein
Submitted name:

Ptpro protein

Gene

Ptpro

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 74 (01 Oct 2014)
      Sequence version 1 (05 Jul 2004)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. protein tyrosine phosphatase activity Source: InterPro

    GO - Biological processi

    1. glomerulus development Source: Ensembl
    2. monocyte chemotaxis Source: Ensembl
    3. negative regulation of glomerular filtration Source: Ensembl

    Keywords - Molecular functioni

    HydrolaseUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Ptpro proteinImported
    Gene namesi
    Name:PtproImported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:1097152. Ptpro.

    Expressioni

    Gene expression databases

    BgeeiQ6P4T4.
    GenevestigatoriQ6P4T4.

    Structurei

    3D structure databases

    ProteinModelPortaliQ6P4T4.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    HOVERGENiHBG053969.
    InParanoidiQ6P4T4.
    PhylomeDBiQ6P4T4.

    Family and domain databases

    Gene3Di2.60.40.10. 1 hit.
    3.90.190.10. 1 hit.
    InterProiIPR003961. Fibronectin_type3.
    IPR013783. Ig-like_fold.
    IPR029021. Prot-tyrosine_phosphatase-like.
    IPR000387. Tyr/Dual-sp_Pase.
    IPR016130. Tyr_Pase_AS.
    IPR000242. Tyr_Pase_rcpt/non-rcpt.
    [Graphical view]
    PfamiPF00041. fn3. 1 hit.
    PF00102. Y_phosphatase. 1 hit.
    [Graphical view]
    PRINTSiPR00700. PRTYPHPHTASE.
    SMARTiSM00060. FN3. 1 hit.
    SM00194. PTPc. 1 hit.
    [Graphical view]
    SUPFAMiSSF49265. SSF49265. 1 hit.
    SSF52799. SSF52799. 1 hit.
    PROSITEiPS50853. FN3. 1 hit.
    PS00383. TYR_PHOSPHATASE_1. 1 hit.
    PS50056. TYR_PHOSPHATASE_2. 1 hit.
    PS50055. TYR_PHOSPHATASE_PTP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q6P4T4-1 [UniParc]FASTAAdd to Basket

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    NSLLYISWTY GDATTDLSHS RMLHWMVVAE GRKKIKKSVT RNVMTAILSL    50
    PPGDIYNLSV TACTERGSNT SLPRLVKLEP APPKSLFAVN KTQTSVTLLW 100
    VEEGVADFFE VFCQQLGSGH NGKLQEPVAV SSHVVTISSL LPATAYNCSV 150
    TSFSHDTPSV PTFIAVSTMV TEVNPNVVVI SVLAILSTLL IGLLLVTLVI 200
    LRKKHLQMAR ECGAGTFVNF ASLEREGKLP YSWRRSVFAL LTLLPSCLWT 250
    DYLLAFYINP WSKNGLKKRK LTNPVQLDDF DSYIKDMAKD SDYKFSLQFE 300
    ELKLIGLDIP HFAADLPLNR CKNRYTNILP YDFSRVRLVS MNEEEGADYI 350
    NANYIPGYNS PQEYIATQGP LPETRNDFWK MVLQQKSHII VMLTQCNEKR 400
    RVKCDHYWPF TEEPIAYGDI TVEMVSEEEE EDWASRHFRI NYADEAQDVM 450
    HFNYTAWPDH GVPPANAAES ILQFVFTVRQ QAAKSKGPMI IHCSAGVGRT 500
    GTFIALDRLL QHIRDHEFVD ILGLVSEMRS YRMSMVQTEE QYIFIHQCVQ 550
    LMWLRKKQQF CISDVIYENV SKS 573
    Length:573
    Mass (Da):65,186
    Last modified:July 5, 2004 - v1
    Checksum:i8AA55B843CCB6D95
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC063258 mRNA. Translation: AAH63258.1.
    UniGeneiMm.186361.
    Mm.491536.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC063258 mRNA. Translation: AAH63258.1 .
    UniGenei Mm.186361.
    Mm.491536.

    3D structure databases

    ProteinModelPortali Q6P4T4.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    MGIi MGI:1097152. Ptpro.

    Phylogenomic databases

    HOVERGENi HBG053969.
    InParanoidi Q6P4T4.
    PhylomeDBi Q6P4T4.

    Miscellaneous databases

    SOURCEi Search...

    Gene expression databases

    Bgeei Q6P4T4.
    Genevestigatori Q6P4T4.

    Family and domain databases

    Gene3Di 2.60.40.10. 1 hit.
    3.90.190.10. 1 hit.
    InterProi IPR003961. Fibronectin_type3.
    IPR013783. Ig-like_fold.
    IPR029021. Prot-tyrosine_phosphatase-like.
    IPR000387. Tyr/Dual-sp_Pase.
    IPR016130. Tyr_Pase_AS.
    IPR000242. Tyr_Pase_rcpt/non-rcpt.
    [Graphical view ]
    Pfami PF00041. fn3. 1 hit.
    PF00102. Y_phosphatase. 1 hit.
    [Graphical view ]
    PRINTSi PR00700. PRTYPHPHTASE.
    SMARTi SM00060. FN3. 1 hit.
    SM00194. PTPc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49265. SSF49265. 1 hit.
    SSF52799. SSF52799. 1 hit.
    PROSITEi PS50853. FN3. 1 hit.
    PS00383. TYR_PHOSPHATASE_1. 1 hit.
    PS50056. TYR_PHOSPHATASE_2. 1 hit.
    PS50055. TYR_PHOSPHATASE_PTP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
      , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: C57BL/6Imported.
      Tissue: BrainImported.

    Entry informationi

    Entry nameiQ6P4T4_MOUSE
    AccessioniPrimary (citable) accession number: Q6P4T4
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 5, 2004
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 74 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)