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Protein
Submitted name:

TRA@ protein

Gene

TRA@

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
TRA@ proteinImported
Gene namesi
Name:TRA@Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi27 ↔ 93Combined sources
Disulfide bondi142 ↔ 192Combined sources

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2NW2X-ray1.40A7-209[»]
4IIQX-ray2.86A6-213[»]
4L4VX-ray1.90D/G6-213[»]
4L8SX-ray2.90A6-213[»]
4L9LX-ray3.40A6-213[»]
4LCCX-ray3.26A6-213[»]
4LCWX-ray2.40D/G6-213[»]
4NQCX-ray2.50D/G6-213[»]
4NQDX-ray2.20D/G6-213[»]
4NQEX-ray2.10D/G6-213[»]
ProteinModelPortaliQ6P4G7.
SMRiQ6P4G7. Positions 7-209.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ6P4G7.

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG017898.

Family and domain databases

Gene3Di2.60.40.10. 2 hits.
InterProiIPR015370. DUF1968.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013106. Ig_V-set.
[Graphical view]
PfamiPF09291. DUF1968. 1 hit.
PF07686. V-set. 1 hit.
[Graphical view]
SMARTiSM00406. IGv. 1 hit.
[Graphical view]
PROSITEiPS50835. IG_LIKE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6P4G7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGGTTGQNID QPTEMTATEG AIVQINCTYQ TSGFNGLFWY QQHAGEAPTF
60 70 80 90 100
LSYNVLDGLE EKGRFSSFLS RSKGYSYLLL KELQMKDSAS YLCAVRDASR
110 120 130 140 150
RGGGNKLTFG TGTQLKVELN IQNPDPAVYQ LRDSKSSDKS VCLFTDFDSQ
160 170 180 190 200
TNVSQSKDSD VYITDKTVLD MRSMDFKSNS AVAWSNKSDF ACANAFNNSI
210 220 230 240 250
IPEDTFFPSP ESSCDVKLVE KSFETDTNLN FQNLSVIGFR ILLLKVAGFN
260
LLMTLRLWSS
Length:260
Mass (Da):28,863
Last modified:July 5, 2004 - v1
Checksum:i582C36C443115052
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC063432 mRNA. Translation: AAH63432.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC063432 mRNA. Translation: AAH63432.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2NW2X-ray1.40A7-209[»]
4IIQX-ray2.86A6-213[»]
4L4VX-ray1.90D/G6-213[»]
4L8SX-ray2.90A6-213[»]
4L9LX-ray3.40A6-213[»]
4LCCX-ray3.26A6-213[»]
4LCWX-ray2.40D/G6-213[»]
4NQCX-ray2.50D/G6-213[»]
4NQDX-ray2.20D/G6-213[»]
4NQEX-ray2.10D/G6-213[»]
ProteinModelPortaliQ6P4G7.
SMRiQ6P4G7. Positions 7-209.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOVERGENiHBG017898.

Miscellaneous databases

ChiTaRSiTRA@. human.
EvolutionaryTraceiQ6P4G7.

Family and domain databases

Gene3Di2.60.40.10. 2 hits.
InterProiIPR015370. DUF1968.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013106. Ig_V-set.
[Graphical view]
PfamiPF09291. DUF1968. 1 hit.
PF07686. V-set. 1 hit.
[Graphical view]
SMARTiSM00406. IGv. 1 hit.
[Graphical view]
PROSITEiPS50835. IG_LIKE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: PancreasImported.
  2. "A T cell receptor flattens a bulged antigenic peptide presented by a major histocompatibility complex class I molecule."
    Tynan F.E., Reid H.H., Kjer-Nielsen L., Miles J.J., Wilce M.C., Kostenko L., Borg N.A., Williamson N.A., Beddoe T., Purcell A.W., Burrows S.R., McCluskey J., Rossjohn J.
    Nat. Immunol. 8:268-276(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.40 ANGSTROMS) OF 7-209, DISULFIDE BONDS.
  3. "Antigen-loaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells."
    Reantragoon R., Corbett A.J., Sakala I.G., Gherardin N.A., Furness J.B., Chen Z., Eckle S.B., Uldrich A.P., Birkinshaw R.W., Patel O., Kostenko L., Meehan B., Kedzierska K., Liu L., Fairlie D.P., Hansen T.H., Godfrey D.I., Rossjohn J., McCluskey J., Kjer-Nielsen L.
    J. Exp. Med. 210:2305-2320(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.40 ANGSTROMS) OF 6-213, DISULFIDE BONDS.
  4. "MAIT recognition of a stimulatory bacterial antigen bound to MR1."
    Lopez-Sagaseta J., Dulberger C.L., McFedries A., Cushman M., Saghatelian A., Adams E.J.
    J. Immunol. 191:5268-5277(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.90 ANGSTROMS) OF 6-213, DISULFIDE BONDS.
  5. "Recognition of vitamin B metabolites by mucosal-associated invariant T cells."
    Patel O., Kjer-Nielsen L., Le Nours J., Eckle S.B., Birkinshaw R., Beddoe T., Corbett A.J., Liu L., Miles J.J., Meehan B., Reantragoon R., Sandoval-Romero M.L., Sullivan L.C., Brooks A.G., Chen Z., Fairlie D.P., McCluskey J., Rossjohn J.
    Nat. Commun. 4:2142-2142(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.90 ANGSTROMS) OF 6-213, DISULFIDE BONDS.
  6. "The molecular basis for Mucosal-Associated Invariant T cell recognition of MR1 proteins."
    Lopez-Sagaseta J., Dulberger C.L., Crooks J.E., Parks C.D., Luoma A.M., McFedries A., Van Rhijn I., Saghatelian A., Adams E.J.
    Proc. Natl. Acad. Sci. U.S.A. 110:E1771-E1778(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.86 ANGSTROMS) OF 6-213, DISULFIDE BONDS.
  7. "T-cell activation by transitory neo-antigens derived from distinct microbial pathways."
    Corbett A.J., Eckle S.B., Birkinshaw R.W., Liu L., Patel O., Mahony J., Chen Z., Reantragoon R., Meehan B., Cao H., Williamson N.A., Strugnell R.A., Van Sinderen D., Mak J.Y., Fairlie D.P., Kjer-Nielsen L., Rossjohn J., McCluskey J.
    Nature 509:361-365(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.10 ANGSTROMS) OF 6-213, DISULFIDE BONDS.

Entry informationi

Entry nameiQ6P4G7_HUMAN
AccessioniPrimary (citable) accession number: Q6P4G7
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: May 27, 2015
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.