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Protein
Submitted name:

PFAS protein

Gene

PFAS

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei568NucleophilePROSITE-ProRule annotation1
Active sitei707PROSITE-ProRule annotation1
Active sitei709PROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
PFAS proteinImported
Gene namesi
Name:PFASImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA33205

PTM / Processingi

Proteomic databases

PeptideAtlasiQ6P4B4
PRIDEiQ6P4B4

Expressioni

Gene expression databases

GenevisibleiQ6P4B4 HS

Structurei

3D structure databases

ProteinModelPortaliQ6P4B4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini474 – 746Glutamine amidotransferase type-1InterPro annotationAdd BLAST273

Keywords - Domaini

Glutamine amidotransferasePROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1907 Eukaryota
COG0046 LUCA
COG0047 LUCA
HOVERGENiHBG108309
KOiK01952

Family and domain databases

Gene3Di3.30.1330.10, 1 hit
3.40.50.880, 1 hit
3.90.650.10, 1 hit
InterProiView protein in InterPro
IPR029062 Class_I_gatase-like
IPR017926 GATASE
IPR010073 PRibForGlyAmidine_synth
IPR010918 PurM-like_C_dom
IPR036676 PurM-like_C_sf
IPR036921 PurM-like_N_sf
PfamiView protein in Pfam
PF02769 AIRS_C, 1 hit
SUPFAMiSSF52317 SSF52317, 1 hit
SSF55326 SSF55326, 1 hit
SSF56042 SSF56042, 1 hit
TIGRFAMsiTIGR01735 FGAM_synt, 1 hit
PROSITEiView protein in PROSITE
PS51273 GATASE_TYPE_1, 1 hit

Sequencei

Sequence statusi: Fragment.

Q6P4B4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
TITGDRRIVL VDDRECPVRR NGQGDAPPTP LPTPVDLELE WVLGKMPRKE
60 70 80 90 100
FFLQRKPPML QPLALPPGLS VHQALERVLR LPAVASKRYL TNKVDRSVGG
110 120 130 140 150
LVAQQQCVGP LQTPLADVAV VALSHEELIG AATALGEQPV KSLLDPKVAA
160 170 180 190 200
RLAVAEALTN LVFALVTDLR DVKCSGNWMW AAKLPGEGAA LADACEAMVA
210 220 230 240 250
VMAALGVAVD GGKDSLSMAA RVGTETVRAP GSLVISAYAV CPDITATVTP
260 270 280 290 300
DLKHPEGRGH LLYVALSPGQ HRLGGTALAQ CFSQLGEHPP DLDLPENLVR
310 320 330 340 350
AFSITQGLLK DRLLCSGHDV SDGGLVTCLL EMAFAGNCGL QVDVPVPRVD
360 370 380 390 400
VLSVLFAEEP GLVLEVQEPD LAQVLKRYRD AGLHCLELGH TGEAGPHAMV
410 420 430 440 450
RVSVNGAVVL EEPVGELRAL WEETSFQLDR LQAEPRCVAE EERGLRERMG
460 470 480 490 500
PSYCLPPTFP KASVPREPGG PSPRVAILRE EGSNGDREMA DAFHLAGFEV
510 520 530 540 550
WDVTMQDLCS GAIGLDTFRG VAFVGGFSYA DVLGSAKGWA AAVTFHPRAG
560 570 580 590 600
AELRRFRKRP DTFSLGVCNG CQLLALLGWV GGDPNEDAAE MGPDSQPARP
610 620 630 640 650
GLLLRHNLSG RYESRWASVR VGPGPALMLR GMEGAVLPVW SAHGEGYVAF
660 670 680 690 700
SSPELQAQIE ARGLAPLHWA DDDGNPTEQY PLNPNGSPGG VAGICSCDGR
710 720 730 740
HLAVMPHPER AVRPWQWAWR PPPFDTLTTS PWLQLFINAR NWTLEGSC
Length:748
Mass (Da):80,186
Last modified:July 5, 2004 - v1
Checksum:i017E6CAC4CDE9CFE
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC063538 mRNA Translation: AAH63538.1
RefSeqiNP_036525.1, NM_012393.2
UniGeneiHs.573976

Genome annotation databases

GeneIDi5198
KEGGihsa:5198

Similar proteinsi

Entry informationi

Entry nameiQ6P4B4_HUMAN
AccessioniPrimary (citable) accession number: Q6P4B4
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: May 23, 2018
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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