Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

PFAS protein

Gene

PFAS

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
PFAS proteinImported
Gene namesi
Name:PFASImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA33205.

PTM / Processingi

Proteomic databases

PaxDbiQ6P4B4.

Expressioni

Gene expression databases

BgeeiQ6P4B4.
GenevisibleiQ6P4B4. HS.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000313490.

Structurei

3D structure databases

ProteinModelPortaliQ6P4B4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini474 – 746273Glutamine amidotransferase type-1InterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG1907. Eukaryota.
COG0046. LUCA.
COG0047. LUCA.
HOVERGENiHBG108309.
KOiK01952.

Family and domain databases

Gene3Di3.30.1330.10. 1 hit.
3.40.50.880. 1 hit.
InterProiIPR010918. AIR_synth_C_dom.
IPR029062. Class_I_gatase-like.
IPR017926. GATASE.
IPR010073. PRibForGlyAmidine_synth.
IPR016188. PurM-like_N.
[Graphical view]
PfamiPF02769. AIRS_C. 1 hit.
[Graphical view]
SUPFAMiSSF52317. SSF52317. 1 hit.
SSF56042. SSF56042. 1 hit.
TIGRFAMsiTIGR01735. FGAM_synt. 1 hit.
PROSITEiPS51273. GATASE_TYPE_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q6P4B4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
TITGDRRIVL VDDRECPVRR NGQGDAPPTP LPTPVDLELE WVLGKMPRKE
60 70 80 90 100
FFLQRKPPML QPLALPPGLS VHQALERVLR LPAVASKRYL TNKVDRSVGG
110 120 130 140 150
LVAQQQCVGP LQTPLADVAV VALSHEELIG AATALGEQPV KSLLDPKVAA
160 170 180 190 200
RLAVAEALTN LVFALVTDLR DVKCSGNWMW AAKLPGEGAA LADACEAMVA
210 220 230 240 250
VMAALGVAVD GGKDSLSMAA RVGTETVRAP GSLVISAYAV CPDITATVTP
260 270 280 290 300
DLKHPEGRGH LLYVALSPGQ HRLGGTALAQ CFSQLGEHPP DLDLPENLVR
310 320 330 340 350
AFSITQGLLK DRLLCSGHDV SDGGLVTCLL EMAFAGNCGL QVDVPVPRVD
360 370 380 390 400
VLSVLFAEEP GLVLEVQEPD LAQVLKRYRD AGLHCLELGH TGEAGPHAMV
410 420 430 440 450
RVSVNGAVVL EEPVGELRAL WEETSFQLDR LQAEPRCVAE EERGLRERMG
460 470 480 490 500
PSYCLPPTFP KASVPREPGG PSPRVAILRE EGSNGDREMA DAFHLAGFEV
510 520 530 540 550
WDVTMQDLCS GAIGLDTFRG VAFVGGFSYA DVLGSAKGWA AAVTFHPRAG
560 570 580 590 600
AELRRFRKRP DTFSLGVCNG CQLLALLGWV GGDPNEDAAE MGPDSQPARP
610 620 630 640 650
GLLLRHNLSG RYESRWASVR VGPGPALMLR GMEGAVLPVW SAHGEGYVAF
660 670 680 690 700
SSPELQAQIE ARGLAPLHWA DDDGNPTEQY PLNPNGSPGG VAGICSCDGR
710 720 730 740
HLAVMPHPER AVRPWQWAWR PPPFDTLTTS PWLQLFINAR NWTLEGSC
Length:748
Mass (Da):80,186
Last modified:July 5, 2004 - v1
Checksum:i017E6CAC4CDE9CFE
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC063538 mRNA. Translation: AAH63538.1.
RefSeqiNP_036525.1. NM_012393.2.
UniGeneiHs.573976.

Genome annotation databases

GeneIDi5198.
KEGGihsa:5198.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC063538 mRNA. Translation: AAH63538.1.
RefSeqiNP_036525.1. NM_012393.2.
UniGeneiHs.573976.

3D structure databases

ProteinModelPortaliQ6P4B4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000313490.

Proteomic databases

PaxDbiQ6P4B4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi5198.
KEGGihsa:5198.

Organism-specific databases

CTDi5198.
PharmGKBiPA33205.

Phylogenomic databases

eggNOGiKOG1907. Eukaryota.
COG0046. LUCA.
COG0047. LUCA.
HOVERGENiHBG108309.
KOiK01952.

Miscellaneous databases

ChiTaRSiPFAS. human.
GenomeRNAii5198.

Gene expression databases

BgeeiQ6P4B4.
GenevisibleiQ6P4B4. HS.

Family and domain databases

Gene3Di3.30.1330.10. 1 hit.
3.40.50.880. 1 hit.
InterProiIPR010918. AIR_synth_C_dom.
IPR029062. Class_I_gatase-like.
IPR017926. GATASE.
IPR010073. PRibForGlyAmidine_synth.
IPR016188. PurM-like_N.
[Graphical view]
PfamiPF02769. AIRS_C. 1 hit.
[Graphical view]
SUPFAMiSSF52317. SSF52317. 1 hit.
SSF56042. SSF56042. 1 hit.
TIGRFAMsiTIGR01735. FGAM_synt. 1 hit.
PROSITEiPS51273. GATASE_TYPE_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: LiverImported.

Entry informationi

Entry nameiQ6P4B4_HUMAN
AccessioniPrimary (citable) accession number: Q6P4B4
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: June 8, 2016
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.