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Q6P3V5

- Q6P3V5_HUMAN

UniProt

Q6P3V5 - Q6P3V5_HUMAN

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Protein
Submitted name:

NOTCH4 protein

Gene
NOTCH4
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. calcium ion binding Source: InterPro
Complete GO annotation...

Keywords - Ligandi

CalciumSAAS annotations

Names & Taxonomyi

Protein namesi
Submitted name:
NOTCH4 proteinImported
Gene namesi
Name:NOTCH4Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotations

Structurei

3D structure databases

ProteinModelPortaliQ6P3V5.

Family & Domainsi

Keywords - Domaini

EGF-like domainUniRule annotationSAAS annotations, RepeatSAAS annotations

Phylogenomic databases

HOVERGENiHBG062449.

Family and domain databases

InterProiIPR000742. EG-like_dom.
IPR001881. EGF-like_Ca-bd_dom.
IPR013032. EGF-like_CS.
IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
IPR018097. EGF_Ca-bd_CS.
IPR009030. Growth_fac_rcpt_N_dom.
[Graphical view]
PfamiPF00008. EGF. 6 hits.
PF07645. EGF_CA. 3 hits.
PF12661. hEGF. 5 hits.
[Graphical view]
SMARTiSM00181. EGF. 7 hits.
SM00179. EGF_CA. 8 hits.
[Graphical view]
SUPFAMiSSF57184. SSF57184. 2 hits.
PROSITEiPS00010. ASX_HYDROXYL. 9 hits.
PS00022. EGF_1. 14 hits.
PS01186. EGF_2. 10 hits.
PS50026. EGF_3. 15 hits.
PS01187. EGF_CA. 9 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6P3V5-1 [UniParc]FASTAAdd to Basket

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MQPPSLLLLL LLLLLLCVSV VRPRGLLCGS FPEPCANGGT CLSLSLGQGT    50
CQCAPGFLGE TCQFPDPCQN AQLCQNGGSC QALLPAPLGL PSSPSPLTPS 100
FLCTCLPGFT GERCQAKLED PCPPSFCSKR GRCHIQASGR PQCSCMPGWT 150
GEQCQLRDFC SANPCVNGGV CLATYPQIQC HCPPGFEGHA CERDVNECFQ 200
DPGPCPKGTS CHNTLGSFQC LCPVGQEGPR CELRAGPCPP RGCSNGGTCQ 250
LMPEKDSTFH LCLCPPGFIG PDCEVNPDNC VSHQCQNGGT CQDGLDTYTC 300
LCPETWTGWD CSEDVDECET QGPPHCRNGG TCQNSAGSFH CVCVSGWGGT 350
SCEENLDDCI AATCAPGSTC IDRVGSFSCL CPPGRTGLLC HLEDMCLSQP 400
CHGDAQCSTN PLTGSTLCLC QPGYSGPTCH QDLDECLMAQ QGPSPCEHGG 450
SCLNTPGSFN CLCPPGYTGS RCEADHNECL SQPCHPGSTC LDLLATFHCL 500
CPPGLEGQLC EVETNECASA PCLNHADCHD LLNGFQCICL PGFSGTRCEE 550
DIDECRSSPC ANGGQCQDQP GAFHCKCLPG FEGPRCQTEV DECLSDPCPV 600
GASCLDLPGA FFCLCPSGFT GSQGRHWKEL AEYFIPFGLG QSSLVGV 647
Length:647
Mass (Da):68,069
Last modified:July 5, 2004 - v1
Checksum:iB71E79AA16E50CE8
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC063815 mRNA. Translation: AAH63815.1.
UniGeneiHs.436100.

Genome annotation databases

UCSCiuc003obc.3. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC063815 mRNA. Translation: AAH63815.1 .
UniGenei Hs.436100.

3D structure databases

ProteinModelPortali Q6P3V5.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

UCSCi uc003obc.3. human.

Phylogenomic databases

HOVERGENi HBG062449.

Family and domain databases

InterProi IPR000742. EG-like_dom.
IPR001881. EGF-like_Ca-bd_dom.
IPR013032. EGF-like_CS.
IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
IPR018097. EGF_Ca-bd_CS.
IPR009030. Growth_fac_rcpt_N_dom.
[Graphical view ]
Pfami PF00008. EGF. 6 hits.
PF07645. EGF_CA. 3 hits.
PF12661. hEGF. 5 hits.
[Graphical view ]
SMARTi SM00181. EGF. 7 hits.
SM00179. EGF_CA. 8 hits.
[Graphical view ]
SUPFAMi SSF57184. SSF57184. 2 hits.
PROSITEi PS00010. ASX_HYDROXYL. 9 hits.
PS00022. EGF_1. 14 hits.
PS01186. EGF_2. 10 hits.
PS50026. EGF_3. 15 hits.
PS01187. EGF_CA. 9 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Peripheral Nervous SystemImported.

Entry informationi

Entry nameiQ6P3V5_HUMAN
AccessioniPrimary (citable) accession number: Q6P3V5
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: January 22, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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