Reviewed,
UniProtKB/Swiss-Prot Q6P3H4 (PNCB_DANRE)
Last modified
February 9, 2010.
Version 35.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Nicotinate phosphoribosyltransferase Short name=NAPRTase EC=2.4.2.11 Alternative name(s): Nicotinate phosphoribosyltransferase domain-containing protein 1 | ||||
| Gene names |
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| Organism | Danio rerio (Zebrafish) (Brachydanio rerio) | ||||
| Taxonomic identifier | 7955 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Cyprinidae › Danio |
Protein attributes
| Sequence length | 546 AA. |
| Sequence status | Complete. |
| Protein existence | Evidence at transcript level. |
General annotation (Comments)
| Function | Catalyzes the conversion of nicotinic acid (NA) to NA mononucleotide (NaMN) By similarity. |
| Catalytic activity | Nicotinate D-ribonucleotide + diphosphate = nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate. |
| Pathway | Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1. |
| Subcellular location | |
| Sequence similarities | Belongs to the NAPRTase family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Pyridine nucleotide biosynthesis |
| Cellular component | Cytoplasm |
| Molecular function | Glycosyltransferase Transferase |
| Gene Ontology (GO) | |
| Biological process | pyridine nucleotide biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW response to oxidative stressInferred from sequence or structural similarity. Source: UniProtKB |
| Cellular component | cytosol Inferred from sequence or structural similarity. Source: UniProtKB |
| Molecular function | nicotinate phosphoribosyltransferase activity Inferred from sequence or structural similarity. Source: UniProtKB |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 546 | 546 | Nicotinate phosphoribosyltransferase | PRO_0000315684 | |||
Sequences
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References
| [1] | NIH - Zebrafish Gene Collection (ZGC) project Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | BC063987 mRNA. Translation: AAH63987.1. Different initiation. |
| IPI | IPI00482634. |
| RefSeq | NP_957184.1. |
| UniGene | Dr.29094 |
3D structure databases | |
| HSSP | HSSP built from PDB template 2F7F based on UniProtKB Q830Y8. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q6P3H4. |
Genome annotation databases | |
| Ensembl | ENSDART00000038157; ENSDARP00000035128; ENSDARG00000027930; Danio rerio. [Genome view] |
| GeneID | 393864. |
| KEGG | dre:393864. |
Organism-specific databases | |
| ZFIN | ZDB-GENE-040426-1897. zgc:77870. |
Phylogenomic databases | |
| eggNOG | fiNOG14216. |
| HOVERGEN | Q6P3H4. |
| InParanoid | Q6P3H4. |
Enzyme and pathway databases | |
| BRENDA | 2.4.2.11. 96826. |
Gene expression databases | |
| Bgee | Q6P3H4. |
Family and domain databases | |
| InterPro | IPR015977. Nic_PRibTrfase-like. IPR006405. Nic_PRibTrfase_put. [Graphical view] |
| Pfam | PF04095. NAPRTase. 2 hits. [Graphical view] |
| TIGRFAMs | TIGR01513. NAPRTase_put. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | PNCB_DANRE | ||||||||
| Accession | Primary (citable) accession number: Q6P3H4 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | Zebrafish annotation project | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with


