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Protein
Submitted name:

Ceruloplasmin

Gene

cp

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseSAAS annotation
LigandCopperSAAS annotation, Metal-bindingSAAS annotation

Enzyme and pathway databases

ReactomeiR-DRE-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
R-DRE-425410 Metal ion SLC transporters
R-DRE-8957275 Post-translational protein phosphorylation
R-DRE-917937 Iron uptake and transport

Names & Taxonomyi

Protein namesi
Submitted name:
CeruloplasminImported
Gene namesi
Name:cpImported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 22

Organism-specific databases

ZFINiZDB-GENE-010522-1 cp

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_501410646821 – 1087Sequence analysisAdd BLAST1067

Expressioni

Gene expression databases

BgeeiENSDARG00000010312

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000015293

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini95 – 205Plastocyanin-likeInterPro annotationAdd BLAST111
Domaini309 – 356Plastocyanin-likeInterPro annotationAdd BLAST48
Domaini449 – 492Plastocyanin-likeInterPro annotationAdd BLAST44
Domaini820 – 913Plastocyanin-likeInterPro annotationAdd BLAST94
Domaini964 – 1072Plastocyanin-likeInterPro annotationAdd BLAST109

Sequence similaritiesi

Belongs to the multicopper oxidase family.SAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG1263 Eukaryota
COG2132 LUCA
GeneTreeiENSGT00910000143988
HOGENOMiHOG000231499
HOVERGENiHBG003674
OMAiVKWYLFG
OrthoDBiEOG091G00QL
TreeFamiTF329807

Family and domain databases

Gene3Di2.60.40.420, 5 hits
InterProiView protein in InterPro
IPR027150 CP
IPR011706 Cu-oxidase_2
IPR011707 Cu-oxidase_3
IPR033138 Cu_oxidase_CS
IPR002355 Cu_oxidase_Cu_BS
IPR008972 Cupredoxin
PANTHERiPTHR44048:SF5 PTHR44048:SF5, 1 hit
PfamiView protein in Pfam
PF07731 Cu-oxidase_2, 2 hits
PF07732 Cu-oxidase_3, 3 hits
SUPFAMiSSF49503 SSF49503, 6 hits
PROSITEiView protein in PROSITE
PS00079 MULTICOPPER_OXIDASE1, 2 hits
PS00080 MULTICOPPER_OXIDASE2, 1 hit

Sequencei

Sequence statusi: Complete.

Q6P3G1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKGLQFALLG VLCCAGIASS ITREYFFAIK EIQWDYAPSG KNLIQNKTVQ
60 70 80 90 100
QDEAARVFLE RGEQRIGRVY KKAVYHQYTD ATYRQEIDKP KWLGYLGPLI
110 120 130 140 150
SAEEDDTVIV HLKNMARRAY SLHAHGLSYN KTNEGALYPD SSEKVEKHDD
160 170 180 190 200
SVAPGTTFTY IWTLPASHAP GKDDTNCLTR IYHSHVNAPK DIASGLIGPL
210 220 230 240 250
IVCKKGSLDV HGDKTGDYLY TLMFTVSDEN LSWYLDENIK TYCSAPAKVN
260 270 280 290 300
KDDEAFQESN KMHSINGYVY GNLPDLSMCI GNKIHWHLFG MGNEVDIHSA
310 320 330 340 350
FFHGQILTDK RQHVDTVSLF PATFVNVEMV ADNPGQWLLS CQVNDHLEAG
360 370 380 390 400
MQAFFEIKKC FPNVHKPRPF GEVRQYYIAA EEIIWDYGPT EINQYTMKKL
410 420 430 440 450
VDDIVSDTFF DNRNDRIGGK YKKVQYVEYT DDTFTKRKEK TPEEQHLGIL
460 470 480 490 500
GPVIRAEEED TIKVTFRNKA SRPFSIQPHG VQYNIDMDGT LYHNVLEESY
510 520 530 540 550
TDKKLRELKK QPRVIEPLPA AMVRPDTTYK YEWVVPKDGG PTEKDPDCLT
560 570 580 590 600
YLYYSAVDPI RDTNSGLVGP LLICKPKTLK SGKQKNVDKE FHLLATVFDE
610 620 630 640 650
NLSWYLDDNI NRYAKQPKSV NKEDADFQES NKMHSLNGYM YGNLKGLNMC
660 670 680 690 700
KGDKVSWHLS GLGSETDIHG LYFEGNRFLY KETRRDTINV FPHISHTVIM
710 720 730 740 750
EPDSMGQFEV NCKTTDHYHG GMRANYTVEK CRFWNRQSET MLHQKKYYIA
760 770 780 790 800
AVEMDWDYSP TRTWEDKMHN GLKESPGNEF LKKEGKFIGS KYKKVLYKEY
810 820 830 840 850
TDETFTKLKE RTADMEHLGI MGPMIHGKVG EKVKIVFKNM ARRPYSIHAH
860 870 880 890 900
GVKTDSPQVA LTRPGETQTY TWYLPKNSGP TEEQEECSVG AYYSTVDVIK
910 920 930 940 950
DMYSGLVGPL VICKKSLART LGLKKEVEEF ALLFMVFDEN ESWYLEENIK
960 970 980 990 1000
THVKNPPKAL TEDQQFIESN KMHGINGLVF GNLKGLNMKV GDKVYWYLMG
1010 1020 1030 1040 1050
LGNEVDIHTA HFHGHSFDYK VSGTHRADVF DLVPGTFQTV TMRPLYSGTW
1060 1070 1080
LLHCHVTDHI QAGMETTYTV LEKDGRKRGF LGIFGSG
Length:1,087
Mass (Da):124,385
Last modified:July 5, 2004 - v1
Checksum:iCC51C01FFC9D5488
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL954145 Genomic DNA No translation available.
BC064000 mRNA Translation: AAH64000.1
UniGeneiDr.3613

Genome annotation databases

EnsembliENSDART00000010537; ENSDARP00000015293; ENSDARG00000010312

Similar proteinsi

Entry informationi

Entry nameiQ6P3G1_DANRE
AccessioniPrimary (citable) accession number: Q6P3G1
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: March 28, 2018
This is version 117 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health