Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase

Gene

alg11

Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

2 GDP-alpha-D-mannose + D-Man-alpha-(1->3)-(D-Man-alpha-(1->6))-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol = 2 GDP + D-Man-alpha-(1->2)-D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-(D-Man-alpha-(1->6))-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferase, Transferase

Protein family/group databases

CAZyiGT4 Glycosyltransferase Family 4

Names & Taxonomyi

Protein namesi
Recommended name:
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase (EC:2.4.1.131)
Alternative name(s):
Asparagine-linked glycosylation protein 11 homolog
Glycolipid 2-alpha-mannosyltransferase
Gene namesi
Name:alg11
OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Taxonomic identifieri8364 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana
Proteomesi
  • UP000008143 Componenti: Unassembled WGS sequence

Organism-specific databases

XenbaseiXB-GENE-5934131 alg11

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei17 – 37HelicalSequence analysisAdd BLAST21
Transmembranei232 – 252HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002956211 – 487GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferaseAdd BLAST487

Proteomic databases

PaxDbiQ6P312
PRIDEiQ6P312

Expressioni

Gene expression databases

BgeeiENSXETG00000020712

Interactioni

Protein-protein interaction databases

STRINGi8364.ENSXETP00000044752

Structurei

3D structure databases

ProteinModelPortaliQ6P312
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG1387 Eukaryota
COG0438 LUCA
GeneTreeiENSGT00550000075118
HOGENOMiHOG000209670
HOVERGENiHBG057178
InParanoidiQ6P312
KOiK03844
OMAiYTGDHEV
OrthoDBiEOG091G0803
TreeFamiTF313056

Family and domain databases

CDDicd03806 GT1_ALG11_like, 1 hit
InterProiView protein in InterPro
IPR038013 ALG11
IPR031814 ALG11_N
IPR001296 Glyco_trans_1
PfamiView protein in Pfam
PF15924 ALG11_N, 1 hit
PF00534 Glycos_transf_1, 1 hit

Sequencei

Sequence statusi: Complete.

Q6P312-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGILCLCGM MRLLTALFIP VLIASIGLCL VLVLLFICTR LWIQRKKKQS
60 70 80 90 100
VEIGKDGKKK RVVAFFHPYC NAGGGGERVL WCALRSLQKR YKDAIYVIYT
110 120 130 140 150
GDKDVSEEQI LNGAAARFNI KLSHPVKFIF LEKRGLVEAS FYPRFTLLGQ
160 170 180 190 200
SLGSVVLGWE ALTKCVPDIY IDSMGYAFTL PLFKYVGGCQ VGCYVHYPTI
210 220 230 240 250
SMDMLSVVRS QNARFNNAAF ISNNPVLSRL KLIYYYLFAV IYGWVGSCSD
260 270 280 290 300
VIMVNSTWTF AHILDLWKCS ERTSIVYPPC DVQTFLDINL NQHKDIEEHS
310 320 330 340 350
IVSIGQFRPE KDHPLQICAF AALLKKKTTE KLKLKLILIG GCRNNEDELR
360 370 380 390 400
VSELKKLSSE LGIPVEFKVN IPFAELKKHL SEATIGLHTM WNEHFGIGIV
410 420 430 440 450
ECMAAGTIIL AHNSGGPKLD IVVPYEEHET GFLADSVESY AAAMDYILCL
460 470 480
TPEQRLTIRQ NARRSVARFS DQEFEANFLA SSEPLFM
Length:487
Mass (Da):54,815
Last modified:July 5, 2004 - v1
Checksum:i50102122875412B0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC064222 mRNA Translation: AAH64222.1
RefSeqiNP_989283.1, NM_203952.1
UniGeneiStr.5877

Genome annotation databases

EnsembliENSXETT00000044752; ENSXETP00000044752; ENSXETG00000020712
GeneIDi394898
KEGGixtr:394898

Similar proteinsi

Entry informationi

Entry nameiALG11_XENTR
AccessioniPrimary (citable) accession number: Q6P312
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 24, 2007
Last sequence update: July 5, 2004
Last modified: May 23, 2018
This is version 78 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health