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Q6P312 (ALG11_XENTR) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase

EC=2.4.1.131
Alternative name(s):
Asparagine-linked glycosylation protein 11 homolog
Glycolipid 2-alpha-mannosyltransferase
Gene names
Name:alg11
OrganismXenopus tropicalis (Western clawed frog) (Silurana tropicalis) [Reference proteome]
Taxonomic identifier8364 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana

Protein attributes

Sequence length487 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

2 GDP-alpha-D-mannose + D-Man-alpha-(1->3)-(D-Man-alpha-(1->6))-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol = 2 GDP + D-Man-alpha-(1->2)-D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-(D-Man-alpha-(1->6))-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol.

Subcellular location

Membrane; Multi-pass membrane protein Potential.

Sequence similarities

Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.

Ontologies

Keywords
   Cellular componentMembrane
   DomainTransmembrane
Transmembrane helix
   Molecular functionGlycosyltransferase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processbiosynthetic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionGDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 487487GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase
PRO_0000295621

Regions

Transmembrane17 – 3721Helical; Potential
Transmembrane232 – 25221Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q6P312 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 50102122875412B0

FASTA48754,815
        10         20         30         40         50         60 
MAGILCLCGM MRLLTALFIP VLIASIGLCL VLVLLFICTR LWIQRKKKQS VEIGKDGKKK 

        70         80         90        100        110        120 
RVVAFFHPYC NAGGGGERVL WCALRSLQKR YKDAIYVIYT GDKDVSEEQI LNGAAARFNI 

       130        140        150        160        170        180 
KLSHPVKFIF LEKRGLVEAS FYPRFTLLGQ SLGSVVLGWE ALTKCVPDIY IDSMGYAFTL 

       190        200        210        220        230        240 
PLFKYVGGCQ VGCYVHYPTI SMDMLSVVRS QNARFNNAAF ISNNPVLSRL KLIYYYLFAV 

       250        260        270        280        290        300 
IYGWVGSCSD VIMVNSTWTF AHILDLWKCS ERTSIVYPPC DVQTFLDINL NQHKDIEEHS 

       310        320        330        340        350        360 
IVSIGQFRPE KDHPLQICAF AALLKKKTTE KLKLKLILIG GCRNNEDELR VSELKKLSSE 

       370        380        390        400        410        420 
LGIPVEFKVN IPFAELKKHL SEATIGLHTM WNEHFGIGIV ECMAAGTIIL AHNSGGPKLD 

       430        440        450        460        470        480 
IVVPYEEHET GFLADSVESY AAAMDYILCL TPEQRLTIRQ NARRSVARFS DQEFEANFLA 


SSEPLFM 

« Hide

References

[1]NIH - Xenopus Gene Collection (XGC) project
Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Embryo.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BC064222 mRNA. Translation: AAH64222.1.
RefSeqNP_989283.1. NM_203952.1.
UniGeneStr.5877.

3D structure databases

ProteinModelPortalQ6P312.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING8364.ENSXETP00000044752.

Protein family/group databases

CAZyGT4. Glycosyltransferase Family 4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSXETT00000044752; ENSXETP00000044752; ENSXETG00000020712.
GeneID394898.
KEGGxtr:394898.

Organism-specific databases

CTD440138.
XenbaseXB-GENE-5934131. alg11.

Phylogenomic databases

eggNOGCOG0438.
GeneTreeENSGT00550000075118.
HOGENOMHOG000209670.
HOVERGENHBG057178.
InParanoidQ6P312.
KOK03844.
OMASEDSYAA.
OrthoDBEOG7FFMRF.
TreeFamTF313056.

Gene expression databases

BgeeQ6P312.

Family and domain databases

InterProIPR001296. Glyco_trans_1.
[Graphical view]
PfamPF00534. Glycos_transf_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameALG11_XENTR
AccessionPrimary (citable) accession number: Q6P312
Entry history
Integrated into UniProtKB/Swiss-Prot: July 24, 2007
Last sequence update: July 5, 2004
Last modified: April 16, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families