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Protein

Tetraspanin

Gene

cd63

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

  • cell surface receptor signaling pathway Source: GO_Central
  • hatching Source: ZFIN

Enzyme and pathway databases

ReactomeiR-DRE-114608 Platelet degranulation
R-DRE-6798695 Neutrophil degranulation

Names & Taxonomyi

Protein namesi
Recommended name:
TetraspaninUniRule annotation
Gene namesi
Name:cd63Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 23

Organism-specific databases

ZFINiZDB-GENE-030131-180 cd63

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei12 – 34HelicalUniRule annotationAdd BLAST23
Transmembranei54 – 74HelicalUniRule annotationAdd BLAST21
Transmembranei81 – 105HelicalUniRule annotationAdd BLAST25
Transmembranei202 – 227HelicalUniRule annotationAdd BLAST26

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSDARG00000025147

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000031764

Family & Domainsi

Sequence similaritiesi

Belongs to the tetraspanin (TM4SF) family.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3882 Eukaryota
ENOG4111IRY LUCA
GeneTreeiENSGT00880000137851
HOGENOMiHOG000230651
HOVERGENiHBG107306
KOiK06497
OMAiCFACCLS
OrthoDBiEOG091G12WV
TreeFamiTF352891

Family and domain databases

Gene3Di1.10.1450.10, 1 hit
InterProiView protein in InterPro
IPR000301 Tetraspanin
IPR018499 Tetraspanin/Peripherin
IPR018503 Tetraspanin_CS
IPR008952 Tetraspanin_EC2_sf
PfamiView protein in Pfam
PF00335 Tetraspannin, 1 hit
PIRSFiPIRSF002419 Tetraspanin, 1 hit
PRINTSiPR00259 TMFOUR
SUPFAMiSSF48652 SSF48652, 1 hit
PROSITEiView protein in PROSITE
PS00421 TM4_1, 1 hit

Sequencei

Sequence statusi: Complete.

Q6P2T9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAVEGGAKCV KYLLFFFNFI FWLCGLALIV LGILVHVSLH NTAILQGASG
60 70 80 90 100
SPMVLIVVGV IIFFISFFGC CGAWKENQCM VVTFAIILSL IVITEIGAGI
110 120 130 140 150
AGYIFRGKVN ELLDQSFNTM IAGYNKTEEY RTTLDSIQKQ LKCCGGNSSS
160 170 180 190 200
DWVNFSADHI SVPDSCCKNV TKNCGIGAMT KPTVIYLEGC QPILETRIKE
210 220 230
NILWIAVGAL VIGFVQITGI VLACILSRAI RSGYEVM
Length:237
Mass (Da):25,758
Last modified:July 5, 2004 - v1
Checksum:iBA4782AEB5E86E1E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU469363 Genomic DNA No translation available.
BC056698 mRNA Translation: AAH56698.1
BC064300 mRNA Translation: AAH64300.1
RefSeqiNP_955837.1, NM_199543.1
UniGeneiDr.76749

Genome annotation databases

EnsembliENSDART00000031047; ENSDARP00000031764; ENSDARG00000025147
GeneIDi321461
KEGGidre:321461

Similar proteinsi

Entry informationi

Entry nameiQ6P2T9_DANRE
AccessioniPrimary (citable) accession number: Q6P2T9
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: March 28, 2018
This is version 98 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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