Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q6P2L6

- NSD3_MOUSE

UniProt

Q6P2L6 - NSD3_MOUSE

Protein

Histone-lysine N-methyltransferase NSD3

Gene

Whsc1l1

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 98 (01 Oct 2014)
      Sequence version 2 (31 Oct 2006)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Histone methyltransferase. Preferentially methylates 'Lys-4' and 'Lys-27' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation, while 'Lys-27' is a mark for transcriptional repression By similarity.By similarity

    Catalytic activityi

    S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri701 – 74848PHD-type 1PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri749 – 80557PHD-type 2PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri862 – 95594PHD-type 3PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri1323 – 137048PHD-type 4; atypicalPROSITE-ProRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. histone-lysine N-methyltransferase activity Source: UniProtKB-EC
    2. zinc ion binding Source: InterPro

    GO - Biological processi

    1. regulation of transcription, DNA-templated Source: UniProtKB-KW
    2. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Molecular functioni

    Chromatin regulator, Methyltransferase, Transferase

    Keywords - Biological processi

    Transcription, Transcription regulation

    Keywords - Ligandi

    Metal-binding, S-adenosyl-L-methionine, Zinc

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Histone-lysine N-methyltransferase NSD3 (EC:2.1.1.43)
    Alternative name(s):
    Nuclear SET domain-containing protein 3
    Wolf-Hirschhorn syndrome candidate 1-like protein 1 homolog
    Short name:
    WHSC1-like protein 1
    Gene namesi
    Name:Whsc1l1
    Synonyms:Nsd3
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 8

    Organism-specific databases

    MGIiMGI:2142581. Whsc1l1.

    Subcellular locationi

    Nucleus By similarity. Chromosome By similarity

    GO - Cellular componenti

    1. chromosome Source: UniProtKB-SubCell
    2. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Chromosome, Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 14391439Histone-lysine N-methyltransferase NSD3PRO_0000259522Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei150 – 1501PhosphoserineBy similarity
    Modified residuei790 – 7901N6-acetyllysine1 Publication

    Keywords - PTMi

    Acetylation, Phosphoprotein

    Proteomic databases

    PaxDbiQ6P2L6.
    PRIDEiQ6P2L6.

    PTM databases

    PhosphoSiteiQ6P2L6.

    Expressioni

    Gene expression databases

    ArrayExpressiQ6P2L6.
    BgeeiQ6P2L6.
    GenevestigatoriQ6P2L6.

    Interactioni

    Subunit structurei

    Interacts with BRD4.By similarity

    Protein-protein interaction databases

    BioGridi231497. 1 interaction.
    IntActiQ6P2L6. 2 interactions.
    MINTiMINT-4110979.

    Structurei

    3D structure databases

    ProteinModelPortaliQ6P2L6.
    SMRiQ6P2L6. Positions 262-332, 700-748, 750-834, 919-1288, 1321-1415.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini270 – 33364PWWP 1PROSITE-ProRule annotationAdd
    BLAST
    Domaini960 – 102566PWWP 2PROSITE-ProRule annotationAdd
    BLAST
    Domaini1096 – 114651AWSPROSITE-ProRule annotationAdd
    BLAST
    Domaini1148 – 1265118SETPROSITE-ProRule annotationAdd
    BLAST
    Domaini1272 – 128817Post-SETPROSITE-ProRule annotationAdd
    BLAST

    Coiled coil

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Coiled coili1036 – 106530Sequence AnalysisAdd
    BLAST

    Sequence similaritiesi

    Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.PROSITE-ProRule annotation
    Contains 1 AWS domain.PROSITE-ProRule annotation
    Contains 4 PHD-type zinc fingers.PROSITE-ProRule annotation
    Contains 1 post-SET domain.PROSITE-ProRule annotation
    Contains 2 PWWP domains.PROSITE-ProRule annotation
    Contains 1 SET domain.PROSITE-ProRule annotation

    Zinc finger

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri701 – 74848PHD-type 1PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri749 – 80557PHD-type 2PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri862 – 95594PHD-type 3PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri1323 – 137048PHD-type 4; atypicalPROSITE-ProRule annotationAdd
    BLAST

    Keywords - Domaini

    Coiled coil, Repeat, Zinc-finger

    Phylogenomic databases

    eggNOGiCOG2940.
    GeneTreeiENSGT00740000114921.
    HOGENOMiHOG000230893.
    HOVERGENiHBG079979.
    InParanoidiQ6P2L6.
    KOiK11425.
    OrthoDBiEOG7Z69BG.

    Family and domain databases

    Gene3Di3.30.40.10. 3 hits.
    InterProiIPR006560. AWS.
    IPR003616. Post-SET_dom.
    IPR000313. PWWP_dom.
    IPR001214. SET_dom.
    IPR019786. Zinc_finger_PHD-type_CS.
    IPR011011. Znf_FYVE_PHD.
    IPR001965. Znf_PHD.
    IPR019787. Znf_PHD-finger.
    IPR013083. Znf_RING/FYVE/PHD.
    [Graphical view]
    PfamiPF00855. PWWP. 2 hits.
    PF00856. SET. 1 hit.
    [Graphical view]
    SMARTiSM00570. AWS. 1 hit.
    SM00249. PHD. 5 hits.
    SM00508. PostSET. 1 hit.
    SM00293. PWWP. 2 hits.
    SM00317. SET. 1 hit.
    [Graphical view]
    SUPFAMiSSF57903. SSF57903. 3 hits.
    PROSITEiPS51215. AWS. 1 hit.
    PS50868. POST_SET. 1 hit.
    PS50812. PWWP. 2 hits.
    PS50280. SET. 1 hit.
    PS01359. ZF_PHD_1. 1 hit.
    PS50016. ZF_PHD_2. 2 hits.
    [Graphical view]

    Sequences (4)i

    Sequence statusi: Complete.

    This entry describes 4 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: Q6P2L6-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MDFSFSFMQG IMGNTIQQPP QLIDSANIRQ EDAFDNHSDI VEDGGPTPFE     50
    ATLQQGFQYP PTTEDLPPLT NGYPPSISLY ETQTKYPPYN QYPNGSANGF 100
    GAVRNFSPTD YYHSEIPNTR PHEILEKPSP PQPPPPPSVP QTVIPKKTGS 150
    PEIKLKITKT IQNGRELFES SLCGDLLNEV QASEHTKSKH ESRKEKRKKS 200
    NRHESSRSEE RRSHKIPKLE PEGQNRPNER VDTAPEKPRE EPVLKEAIPV 250
    QPILSSVPTT ETSTGVKFQV GDLVWSKVGT YPWWPCMVSS DPQLEVHSKI 300
    NTRGAREYHV QFFSNQPERA WVHEKRVREY KGHEQYEELL AEAAKQASNH 350
    SEKQKIRKPR PQRERAQWDI GIAHAEKALK MTREERVEQY TFIYIDKQPE 400
    EASSQAKKNV TSKTEVKKPR RPRSVLNSQP EQTNAGEVAS SQSSTDLRRQ 450
    SQRRHTSLEE EEPPPVKIAW KTAAARKSLP ASITMHKGSL DLQKCNMSPV 500
    VKIEQVFALQ NATGDGKFID QFVYSTKGIG NKTEISVRGQ DRLIISSPSQ 550
    RSEKPAQSAS SPEATSGSAG PVEKKQQRRS IRTRSESEKS AEVVPKKKIK 600
    KEQVETAPQA SLKTGLQKGA SEISDSCKPL KKRSRASTDV ETASCTYRDT 650
    SDSDSRGLSD GQVGFGKQVD SPSATADADA SDAQSVDSSL SRRGVGTSKK 700
    DTVCQVCEKA GDCLVACEGE CCRHFHVECL GLTAVPEGHF TCEECETGQH 750
    PCFSCKVSGK DVKRCSVSVC GKFYHEACVR KFPTAIFESK GFRCPQHCCS 800
    SCSMEKDIHK ASKGRMMRCL RCPVAYHVGD ACVAAGSVSV SSHILICSNH 850
    SKRSSQSAAI NVGFCFVCAR GLIVQDHSDP MFSSYAYKSH YLLSESNRAE 900
    LMKLPMIPSS SASKKRCEKG GRLLCCESCP ASFHPECLSI DMPEGCWNCN 950
    DCKAGKKLHY KQIVWVKLGN YRQVLWWPAE ICSPRSVPLN IQGLKHDLGD 1000
    FPVFFFGSHD YYWVHQGRVF PYVEGDKHFA EGQTSINKTF KKALEEAAKR 1050
    FQELKAQRES KEALEMERTS RKPPPYKHIK ANKVIGKVQV QVADLSEIPR 1100
    CNCKPGDENP CGLESQCLNR MSQYECHPQV CPAGDRCQNQ CFTKRLYPDA 1150
    EVIKTERRGW GLRTKRSIKK GEFVNEYVGE LIDEEECRLR IKRAHENSVT 1200
    NFYMLTVTKD RIIDAGPKGN YSRFMNHSCN PNCETQKWTV NGDVRVGLFA 1250
    LCDIPAGMEL TFNYNLDCLG NGRTVCHCGA DNCSGFLGVR PKSACTSAVD 1300
    EKTKNAKLKK RRKVKAEAKP IHEDYCFQCG DGGELVMCDK KDCPKAYHLL 1350
    CLNLTQPPHG KWECPWHRCD ECGSVAVSFC EFCPHSFCKA HGKGALVPSA 1400
    LEGRLCCSSH DPASPVSPEY WSKIRCKWES QDSGEEVKE 1439
    Length:1,439
    Mass (Da):161,002
    Last modified:October 31, 2006 - v2
    Checksum:i917C7ADCD1248525
    GO
    Isoform 2 (identifier: Q6P2L6-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         135-135: P → PLPPPPPPPPP
         620-645: ASEISDSCKPLKKRSRASTDVETASC → SADRGAQGSVRFSDSSVSAAKEETVD
         646-1439: Missing.

    Show »
    Length:655
    Mass (Da):73,380
    Checksum:i358CBD840A5A47C6
    GO
    Isoform 3 (identifier: Q6P2L6-3) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1-941: Missing.
         973-975: Missing.
         1199-1209: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:484
    Mass (Da):54,977
    Checksum:i562572C7B3100FD4
    GO
    Isoform 4 (identifier: Q6P2L6-4) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         135-135: P → PLPPPPPPPPP
         603-611: QVETAPQAS → QVGFLHVES
         612-1439: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:621
    Mass (Da):70,000
    Checksum:i5553A83F48BF9B16
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti122 – 1221H → R in BAE33834. (PubMed:16141072)Curated
    Sequence conflicti950 – 9501N → K in BAE21322. (PubMed:16141072)Curated
    Sequence conflicti1149 – 11491D → N in BAE21322. (PubMed:16141072)Curated

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei1 – 941941Missing in isoform 3. 1 PublicationVSP_021431Add
    BLAST
    Alternative sequencei135 – 1351P → PLPPPPPPPPP in isoform 2 and isoform 4. 2 PublicationsVSP_021432
    Alternative sequencei603 – 6119QVETAPQAS → QVGFLHVES in isoform 4. 1 PublicationVSP_021433
    Alternative sequencei612 – 1439828Missing in isoform 4. 1 PublicationVSP_021434Add
    BLAST
    Alternative sequencei620 – 64526ASEIS…ETASC → SADRGAQGSVRFSDSSVSAA KEETVD in isoform 2. 2 PublicationsVSP_021435Add
    BLAST
    Alternative sequencei646 – 1439794Missing in isoform 2. 2 PublicationsVSP_021436Add
    BLAST
    Alternative sequencei973 – 9753Missing in isoform 3. 1 PublicationVSP_021437
    Alternative sequencei1199 – 120911Missing in isoform 3. 1 PublicationVSP_021438Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK079952 mRNA. Translation: BAC37792.1.
    AK132725 mRNA. Translation: BAE21322.1.
    AK156746 mRNA. Translation: BAE33834.1.
    AK170040 mRNA. Translation: BAE41526.1.
    AC156990 Genomic DNA. No translation available.
    AC162367 Genomic DNA. No translation available.
    BC064447 mRNA. Translation: AAH64447.1.
    CCDSiCCDS40305.1. [Q6P2L6-2]
    RefSeqiNP_001001735.1. NM_001001735.1. [Q6P2L6-2]
    XP_006509168.1. XM_006509105.1. [Q6P2L6-2]
    UniGeneiMm.217337.

    Genome annotation databases

    EnsembliENSMUST00000146919; ENSMUSP00000115470; ENSMUSG00000054823. [Q6P2L6-2]
    ENSMUST00000155861; ENSMUSP00000117596; ENSMUSG00000054823. [Q6P2L6-2]
    GeneIDi234135.
    KEGGimmu:234135.
    UCSCiuc009lgk.1. mouse. [Q6P2L6-4]
    uc009lgm.1. mouse. [Q6P2L6-2]
    uc009lgp.1. mouse. [Q6P2L6-3]

    Keywords - Coding sequence diversityi

    Alternative splicing

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK079952 mRNA. Translation: BAC37792.1 .
    AK132725 mRNA. Translation: BAE21322.1 .
    AK156746 mRNA. Translation: BAE33834.1 .
    AK170040 mRNA. Translation: BAE41526.1 .
    AC156990 Genomic DNA. No translation available.
    AC162367 Genomic DNA. No translation available.
    BC064447 mRNA. Translation: AAH64447.1 .
    CCDSi CCDS40305.1. [Q6P2L6-2 ]
    RefSeqi NP_001001735.1. NM_001001735.1. [Q6P2L6-2 ]
    XP_006509168.1. XM_006509105.1. [Q6P2L6-2 ]
    UniGenei Mm.217337.

    3D structure databases

    ProteinModelPortali Q6P2L6.
    SMRi Q6P2L6. Positions 262-332, 700-748, 750-834, 919-1288, 1321-1415.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 231497. 1 interaction.
    IntActi Q6P2L6. 2 interactions.
    MINTi MINT-4110979.

    PTM databases

    PhosphoSitei Q6P2L6.

    Proteomic databases

    PaxDbi Q6P2L6.
    PRIDEi Q6P2L6.

    Protocols and materials databases

    DNASUi 234135.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000146919 ; ENSMUSP00000115470 ; ENSMUSG00000054823 . [Q6P2L6-2 ]
    ENSMUST00000155861 ; ENSMUSP00000117596 ; ENSMUSG00000054823 . [Q6P2L6-2 ]
    GeneIDi 234135.
    KEGGi mmu:234135.
    UCSCi uc009lgk.1. mouse. [Q6P2L6-4 ]
    uc009lgm.1. mouse. [Q6P2L6-2 ]
    uc009lgp.1. mouse. [Q6P2L6-3 ]

    Organism-specific databases

    CTDi 54904.
    MGIi MGI:2142581. Whsc1l1.

    Phylogenomic databases

    eggNOGi COG2940.
    GeneTreei ENSGT00740000114921.
    HOGENOMi HOG000230893.
    HOVERGENi HBG079979.
    InParanoidi Q6P2L6.
    KOi K11425.
    OrthoDBi EOG7Z69BG.

    Miscellaneous databases

    ChiTaRSi WHSC1L1. mouse.
    NextBioi 382034.
    PROi Q6P2L6.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q6P2L6.
    Bgeei Q6P2L6.
    Genevestigatori Q6P2L6.

    Family and domain databases

    Gene3Di 3.30.40.10. 3 hits.
    InterProi IPR006560. AWS.
    IPR003616. Post-SET_dom.
    IPR000313. PWWP_dom.
    IPR001214. SET_dom.
    IPR019786. Zinc_finger_PHD-type_CS.
    IPR011011. Znf_FYVE_PHD.
    IPR001965. Znf_PHD.
    IPR019787. Znf_PHD-finger.
    IPR013083. Znf_RING/FYVE/PHD.
    [Graphical view ]
    Pfami PF00855. PWWP. 2 hits.
    PF00856. SET. 1 hit.
    [Graphical view ]
    SMARTi SM00570. AWS. 1 hit.
    SM00249. PHD. 5 hits.
    SM00508. PostSET. 1 hit.
    SM00293. PWWP. 2 hits.
    SM00317. SET. 1 hit.
    [Graphical view ]
    SUPFAMi SSF57903. SSF57903. 3 hits.
    PROSITEi PS51215. AWS. 1 hit.
    PS50868. POST_SET. 1 hit.
    PS50812. PWWP. 2 hits.
    PS50280. SET. 1 hit.
    PS01359. ZF_PHD_1. 1 hit.
    PS50016. ZF_PHD_2. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The transcriptional landscape of the mammalian genome."
      Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
      , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
      Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2; 3 AND 4).
      Strain: C57BL/6J and NOD.
      Tissue: Aorta, Spleen, Testis and Vein.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6J.
    3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
      Strain: C57BL/6.
      Tissue: Brain.
    4. Lubec G., Sunyer B., Chen W.-Q.
      Submitted (JAN-2009) to UniProtKB
      Cited for: PROTEIN SEQUENCE OF 899-914, IDENTIFICATION BY MASS SPECTROMETRY.
      Strain: OF1.
      Tissue: Hippocampus.
    5. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Liver.
    6. "The phagosomal proteome in interferon-gamma-activated macrophages."
      Trost M., English L., Lemieux S., Courcelles M., Desjardins M., Thibault P.
      Immunity 30:143-154(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    7. "SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
      Park J., Chen Y., Tishkoff D.X., Peng C., Tan M., Dai L., Xie Z., Zhang Y., Zwaans B.M., Skinner M.E., Lombard D.B., Zhao Y.
      Mol. Cell 50:919-930(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-790, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Embryonic fibroblast.

    Entry informationi

    Entry nameiNSD3_MOUSE
    AccessioniPrimary (citable) accession number: Q6P2L6
    Secondary accession number(s): Q3TDS4
    , Q3U0L8, Q3V131, Q8BJT3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 31, 2006
    Last sequence update: October 31, 2006
    Last modified: October 1, 2014
    This is version 98 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Direct protein sequencing, Reference proteome

    Documents

    1. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3