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Protein
Submitted name:

CD40 protein

Gene

CD40

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
CD40 proteinImported
Gene namesi
Name:CD40Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_500427882321 – 151Sequence analysisAdd BLAST131

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi38 ↔ 51PROSITE-ProRule annotation
Disulfide bondi41 ↔ 59PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotation

Proteomic databases

PeptideAtlasiQ6P2H9

Structurei

3D structure databases

ProteinModelPortaliQ6P2H9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini25 – 59TNFR-CysInterPro annotationAdd BLAST35
Repeati25 – 59TNFR-CysPROSITE-ProRule annotationAdd BLAST35

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

KOiK03160

Family and domain databases

InterProiView protein in InterPro
IPR001368 TNFR/NGFR_Cys_rich_reg
IPR020435 TNFR_5
PRINTSiPR01922 TNFACTORR5
SMARTiView protein in SMART
SM00208 TNFR, 3 hits
PROSITEiView protein in PROSITE
PS00652 TNFR_NGFR_1, 1 hit
PS50050 TNFR_NGFR_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q6P2H9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVRLPLQCVL WGCLLTAVHP EPPTACREKQ YLINSQCCSL CQPGQKLVSD
60 70 80 90 100
CTEFTETECL PCGESEFLDT WNRETHFHQH KYCDPNLGLR VQQKGTSETD
110 120 130 140 150
TICTCEEGWH CTSEACESCV LHRSCSPGFG VKQIDICQPH FPKDRGLNLL

M
Length:151
Mass (Da):17,079
Last modified:July 5, 2004 - v1
Checksum:iEBAA27CE7592172B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC064518 mRNA Translation: AAH64518.1
RefSeqiNP_001241.1, NM_001250.5
NP_001289682.1, NM_001302753.1
NP_690593.1, NM_152854.3
UniGeneiHs.472860

Genome annotation databases

GeneIDi958
KEGGihsa:958

Similar proteinsi

Entry informationi

Entry nameiQ6P2H9_HUMAN
AccessioniPrimary (citable) accession number: Q6P2H9
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: May 23, 2018
This is version 69 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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