##gff-version 3 Q6P2H3 UniProtKB Chain 1 762 . . . ID=PRO_0000233660;Note=Centrosomal protein of 85 kDa Q6P2H3 UniProtKB Region 1 26 . . . Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite Q6P2H3 UniProtKB Region 94 119 . . . Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite Q6P2H3 UniProtKB Region 257 433 . . . Note=Mediates interaction with NEK2 and is required for its function in the suppression of centrosome disjunction;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:26220856;Dbxref=PMID:26220856 Q6P2H3 UniProtKB Region 434 476 . . . Note=Required for centrosome localization and for its function in the suppression of centrosome disjunction;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:26220856;Dbxref=PMID:26220856 Q6P2H3 UniProtKB Region 443 474 . . . Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite Q6P2H3 UniProtKB Region 541 570 . . . Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite Q6P2H3 UniProtKB Coiled coil 334 657 . . . Ontology_term=ECO:0000255;evidence=ECO:0000255 Q6P2H3 UniProtKB Coiled coil 723 750 . . . Ontology_term=ECO:0000255;evidence=ECO:0000255 Q6P2H3 UniProtKB Compositional bias 10 26 . . . Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite Q6P2H3 UniProtKB Compositional bias 541 558 . . . Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite Q6P2H3 UniProtKB Modified residue 17 17 . . . Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:18669648;Dbxref=PMID:18669648 Q6P2H3 UniProtKB Modified residue 126 126 . . . Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:23186163;Dbxref=PMID:23186163 Q6P2H3 UniProtKB Modified residue 141 141 . . . Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:23186163;Dbxref=PMID:23186163 Q6P2H3 UniProtKB Modified residue 623 623 . . . Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:20068231;Dbxref=PMID:20068231 Q6P2H3 UniProtKB Alternative sequence 1 568 . . . ID=VSP_026435;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 Q6P2H3 UniProtKB Alternative sequence 19 70 . . . ID=VSP_055609;Note=In isoform 4. SSDVIQKGSSLGTEWQTPVISEPFRSRFSRCSSVADSGDTAIGTSCSDIAED->N;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039 Q6P2H3 UniProtKB Alternative sequence 710 711 . . . ID=VSP_018147;Note=In isoform 2. SA->S;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:14702039,ECO:0000303|PubMed:17974005;Dbxref=PMID:14702039,PMID:17974005 Q6P2H3 UniProtKB Natural variant 48 48 . . . ID=VAR_053938;Note=R->H;Dbxref=dbSNP:rs35831900 Q6P2H3 UniProtKB Natural variant 213 213 . . . ID=VAR_053939;Note=S->N;Dbxref=dbSNP:rs3795686 Q6P2H3 UniProtKB Natural variant 542 542 . . . ID=VAR_033665;Note=A->T;Dbxref=dbSNP:rs7550997 Q6P2H3 UniProtKB Natural variant 668 668 . . . ID=VAR_053940;Note=Q->H;Dbxref=dbSNP:rs36013141 Q6P2H3 UniProtKB Mutagenesis 640 640 . . . Note=Strongly reduced interaction with STIL. Strongly reduced interaction with STIL%3B when associated with A-644. Does not affect interaction wit PLKA%3B when associated with A-644. Q->A;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:29712910,ECO:0000269|PubMed:32107292;Dbxref=PMID:29712910,PMID:32107292 Q6P2H3 UniProtKB Mutagenesis 644 644 . . . Note=Strongly reduced interaction with STIL. Strongly reduced interaction with STIL%3B when associated with A-640. Does not affect interaction wit PLKA%3B when associated with A-644. E->A;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:29712910,ECO:0000269|PubMed:32107292;Dbxref=PMID:29712910,PMID:32107292 Q6P2H3 UniProtKB Sequence conflict 258 260 . . . Note=LSK->HSSQ;Ontology_term=ECO:0000305;evidence=ECO:0000305 Q6P2H3 UniProtKB Sequence conflict 517 517 . . . Note=E->G;Ontology_term=ECO:0000305;evidence=ECO:0000305 Q6P2H3 UniProtKB Sequence conflict 561 561 . . . Note=S->G;Ontology_term=ECO:0000305;evidence=ECO:0000305 Q6P2H3 UniProtKB Helix 572 652 . . . Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:5OI7