SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q6P200

- Q6P200_MOUSE

UniProt

Q6P200 - Q6P200_MOUSE

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name: Cytochrome P450, family 17, subfamily a, polypeptide 1
Gene
Cyp17a1
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. heme binding Source: InterPro
  2. iron ion binding Source: InterPro
  3. steroid 17-alpha-monooxygenase activity Source: MGI

GO - Biological processi

  1. glucocorticoid biosynthetic process Source: MGI
Complete GO annotation...

Keywords - Molecular functioni

MonooxygenaseUniRule annotation, Oxidoreductase

Keywords - Ligandi

HemeUniRule annotation, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Cytochrome P450, family 17, subfamily a, polypeptide 1Imported
Gene namesi
Name:Cyp17a1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:88586. Cyp17a1.

Subcellular locationi

GO - Cellular componenti

  1. axon Source: MGI
  2. mitochondrion Source: MGI
  3. neuronal cell body Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

GenevestigatoriQ6P200.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000026012.

Structurei

3D structure databases

ProteinModelPortaliQ6P200.

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome P450 family.UniRule annotation

Phylogenomic databases

HOVERGENiHBG106944.
InParanoidiQ6P200.

Family and domain databases

Gene3Di1.10.630.10. 1 hit.
InterProiIPR001128. Cyt_P450.
IPR017972. Cyt_P450_CS.
IPR002401. Cyt_P450_E_grp-I.
[Graphical view]
PfamiPF00067. p450. 1 hit.
[Graphical view]
PRINTSiPR00463. EP450I.
PR00385. P450.
SUPFAMiSSF48264. SSF48264. 1 hit.
PROSITEiPS00086. CYTOCHROME_P450. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6P200-1 [UniParc]FASTAAdd to Basket

« Hide

MWELVGLLLL ILAYFFWPKS KTPNAKFPRS LPFLPLVGSL PFLPRRGHMH    50
ANFFKLQEKY GPIYSLRLGT TTAVIVGHYQ LAREVLVKKG KEFSGRPQMV 100
TLGLLSDQGK GVAFADSSSS WQLHRKLVFS TFSLFRDDQK LEKMICQEAN 150
SLCDLILTYD GESRDLSTLI FKSVINIICT ICFNISFENK DPILTTIQTF 200
TEGIVDVLGH SDLVDIFPWL KIFPNKNLEM IKEHTKIREK TLVEMFEKCK 250
EKFNSESLSS LTDILIQAKM NAENNNTGEG QDPSVFSDKH ILVTVGDIFG 300
AGIETTSSVL SWILAFLVHN PEVKRKIQKE IDQYVGFSRT PSFNDRTHLL 350
MLEATIREVL RIRPVAPLLI PHKANIDSSI GEFAIPKDTH VIINLWALHH 400
DKNEWDQPDR FMPERFLDPT GSHLITPTPS YLPFGAGPRS CIGEALARQE 450
LFIFMALLLQ RFDFDVSDDK QLPCLVGDPK VVFLIDPFKV KITVRQAWKD 500
AQVEVST 507
Length:507
Mass (Da):57,611
Last modified:July 5, 2004 - v1
Checksum:iF548788917A6057E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC064793 mRNA. Translation: AAH64793.1.
UniGeneiMm.1262.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC064793 mRNA. Translation: AAH64793.1 .
UniGenei Mm.1262.

3D structure databases

ProteinModelPortali Q6P200.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10090.ENSMUSP00000026012.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

MGIi MGI:88586. Cyp17a1.

Phylogenomic databases

HOVERGENi HBG106944.
InParanoidi Q6P200.

Miscellaneous databases

SOURCEi Search...

Gene expression databases

Genevestigatori Q6P200.

Family and domain databases

Gene3Di 1.10.630.10. 1 hit.
InterProi IPR001128. Cyt_P450.
IPR017972. Cyt_P450_CS.
IPR002401. Cyt_P450_E_grp-I.
[Graphical view ]
Pfami PF00067. p450. 1 hit.
[Graphical view ]
PRINTSi PR00463. EP450I.
PR00385. P450.
SUPFAMi SSF48264. SSF48264. 1 hit.
PROSITEi PS00086. CYTOCHROME_P450. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6JImported.
    Tissue: EmbryoImported.

Entry informationi

Entry nameiQ6P200_MOUSE
AccessioniPrimary (citable) accession number: Q6P200
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: January 22, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi