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Protein

Uncharacterized protein C1orf94

Gene

C1orf94

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein C1orf94
Gene namesi
Name:C1orf94
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000142698.14.
HGNCiHGNC:28250. C1orf94.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000142698.
PharmGKBiPA142672478.

Polymorphism and mutation databases

BioMutaiC1orf94.
DMDMi357528782.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002800971 – 598Uncharacterized protein C1orf94Add BLAST598

Proteomic databases

EPDiQ6P1W5.
PaxDbiQ6P1W5.
PeptideAtlasiQ6P1W5.
PRIDEiQ6P1W5.

PTM databases

iPTMnetiQ6P1W5.
PhosphoSitePlusiQ6P1W5.

Expressioni

Gene expression databases

BgeeiENSG00000142698.
CleanExiHS_C1orf94.
GenevisibleiQ6P1W5. HS.

Organism-specific databases

HPAiHPA045805.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
B2R8Y43EBI-946029,EBI-10175581
AESQ081173EBI-946029,EBI-717810
AKAP9Q99996-23EBI-946029,EBI-9641546
ATRIPQ8WXE13EBI-946029,EBI-747353
ATXN1P542538EBI-946029,EBI-930964
BANPQ8N9N53EBI-946029,EBI-744695
BOLA1Q9Y3E23EBI-946029,EBI-1049556
BOLLQ8N9W63EBI-946029,EBI-998198
BYSLQ138953EBI-946029,EBI-358049
C1orf109Q9NX043EBI-946029,EBI-8643161
CARD9Q9H2573EBI-946029,EBI-751319
CCHCR1Q8TD31-34EBI-946029,EBI-10175300
CCNJLF6RF563EBI-946029,EBI-10177725
CDKN2DP552734EBI-946029,EBI-745859
CFAP206Q8IYR04EBI-946029,EBI-749051
CRYBA4P536733EBI-946029,EBI-7519711
DAB1O755533EBI-946029,EBI-7875264
DAZAP2Q150386EBI-946029,EBI-724310
DOK6Q6PKX43EBI-946029,EBI-2880244
DTX2Q86UW93EBI-946029,EBI-740376
FAM168AQ925673EBI-946029,EBI-7957930
FAM46DQ8NEK83EBI-946029,EBI-744726
GCC1Q96CN93EBI-946029,EBI-746252
GORASP2Q9H8Y85EBI-946029,EBI-739467
GRB2P629933EBI-946029,EBI-401755
GSE1Q146875EBI-946029,EBI-372619
HNRNPFP525975EBI-946029,EBI-352986
Hoxa1P090223EBI-946029,EBI-3957603From Mus musculus.
IPO11Q9UI263EBI-946029,EBI-748752
KLHL32Q5THT13EBI-946029,EBI-10247181
LMO2P257913EBI-946029,EBI-739696
MAGED1Q9Y5V33EBI-946029,EBI-716006
MAPK1IP1LQ8NDC04EBI-946029,EBI-741424
MAPK9P459843EBI-946029,EBI-713568
MEIS2O147703EBI-946029,EBI-2804934
NFKBIDQ8NI385EBI-946029,EBI-10271199
NGBQ9NPG23EBI-946029,EBI-10311409
OAZ3Q9UMX23EBI-946029,EBI-10281601
OIP5O434823EBI-946029,EBI-536879
PLEKHB2Q96CS73EBI-946029,EBI-373552
PRKAG1P546193EBI-946029,EBI-1181439
PRR20CP864793EBI-946029,EBI-10172814
R3HDM2Q9Y2K5-23EBI-946029,EBI-10326419
RAD51DO757716EBI-946029,EBI-1055693
RBFOX1Q9NWB13EBI-946029,EBI-945906
RBFOX2O432513EBI-946029,EBI-746056
RBM47B7ZLP73EBI-946029,EBI-10176148
RBPMSQ930624EBI-946029,EBI-740322
ROR2A1L4F53EBI-946029,EBI-10172778
SMAP2Q8WU793EBI-946029,EBI-2822515
TBX6O959473EBI-946029,EBI-2824328
TNPO2O147873EBI-946029,EBI-431907
TSC1Q86WV84EBI-946029,EBI-12806590
TXNDC9O145303EBI-946029,EBI-707554
VENTXO952313EBI-946029,EBI-10191303
VPS37CA5D8V65EBI-946029,EBI-2559305
YES1P079473EBI-946029,EBI-515331

Protein-protein interaction databases

BioGridi124400. 72 interactors.
IntActiQ6P1W5. 82 interactors.
MINTiMINT-2855222.
STRINGi9606.ENSP00000435634.

Structurei

3D structure databases

ProteinModelPortaliQ6P1W5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi467 – 470Poly-Pro4

Phylogenomic databases

eggNOGiENOG410IKBB. Eukaryota.
ENOG410YE9F. LUCA.
GeneTreeiENSGT00390000017672.
HOGENOMiHOG000049257.
HOVERGENiHBG080475.
InParanoidiQ6P1W5.
OMAiDGPQYLF.
OrthoDBiEOG091G0X8U.
PhylomeDBiQ6P1W5.
TreeFamiTF338566.

Family and domain databases

InterProiView protein in InterPro
IPR031496. DUF4688.
PfamiView protein in Pfam
PF15752. DUF4688. 1 hit.

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q6P1W5-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MRGGGGCVLA LGGQRGFQKE RRRMASGNGL PSSSALVAKG PCALGPFPRY
60 70 80 90 100
IWIHQDTPQD SLDKTCHEIW KRVQGLPEAS QPWTSMEQLS VPVVGTLRGN
110 120 130 140 150
ELSFQEEALE LSSGKDEISL LVEQEFLSLT KEHSILVEES SGELEVPGSS
160 170 180 190 200
PEGTRELAPC ILAPPLVAGS NERPRASIIV GDKLLKQKVA MPVISSRQDC
210 220 230 240 250
DSATSTVTDI LCAAEVKSSK GTEDRGRILG DSNLQVSKLL SQFPLKSTET
260 270 280 290 300
SKVPDNKNVL DKTRVTKDFL QDNLFSGPGP KEPTGLSPFL LLPPRPPPAR
310 320 330 340 350
PDKLPELPAQ KRQLPVFAKI CSKPKADPAV ERHHLMEWSP GTKEPKKGQG
360 370 380 390 400
SLFLSQWPQS QKDACGEEGC CDAVGTASLT LPPKKPTCPA EKNLLYEFLG
410 420 430 440 450
ATKNPSGQPR LRNKVEVDGP ELKFNAPVTV ADKNNPKYTG NVFTPHFPTA
460 470 480 490 500
MTSATLNQPL WLNLNYPPPP VFTNHSTFLQ YQGLYPQQAA RMPYQQALHP
510 520 530 540 550
QLGCYSQQVM PYNPQQMGQQ IFRSSYTPLL SYIPFVQPNY PYPQRTPPKM
560 570 580 590
SANPRDPPLM AGDGPQYLFP QGYGFGSTSG GPLMHSPYFS SSGNGINF
Length:598
Mass (Da):65,353
Last modified:November 16, 2011 - v2
Checksum:iAAD349072B925A8E
GO
Isoform 2 (identifier: Q6P1W5-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-190: Missing.

Show »
Length:408
Mass (Da):44,902
Checksum:i5B1E356339E5941C
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_031051235Q → E1 PublicationCorresponds to variant dbSNP:rs1382602Ensembl.1
Natural variantiVAR_031052302D → E1 PublicationCorresponds to variant dbSNP:rs1414474Ensembl.1
Natural variantiVAR_050702438Y → H. Corresponds to variant dbSNP:rs17556981Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_0420321 – 190Missing in isoform 2. 2 PublicationsAdd BLAST190

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK123355 mRNA. Translation: BAG53893.1.
AC115286 Genomic DNA. No translation available.
CH471059 Genomic DNA. Translation: EAX07445.1.
CH471059 Genomic DNA. Translation: EAX07446.1.
BC007637 mRNA. Translation: AAH07637.1.
BC064845 mRNA. Translation: AAH64845.1.
CCDSiCCDS381.1. [Q6P1W5-2]
CCDS44108.1. [Q6P1W5-1]
RefSeqiNP_001128206.1. NM_001134734.1. [Q6P1W5-1]
NP_116273.2. NM_032884.4. [Q6P1W5-2]
UniGeneiHs.194610.

Genome annotation databases

EnsembliENST00000373374; ENSP00000362472; ENSG00000142698. [Q6P1W5-2]
ENST00000488417; ENSP00000435634; ENSG00000142698. [Q6P1W5-1]
GeneIDi84970.
KEGGihsa:84970.
UCSCiuc001bxs.6. human. [Q6P1W5-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Similar proteinsi

Entry informationi

Entry nameiCA094_HUMAN
AccessioniPrimary (citable) accession number: Q6P1W5
Secondary accession number(s): B3KVT1
, D3DPR3, E9PJ76, Q96IC8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 6, 2007
Last sequence update: November 16, 2011
Last modified: October 25, 2017
This is version 105 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations