Reviewed, UniProtKB/Swiss-Prot Q6P1W5 (CA094_HUMAN)

Names and origin

Protein names

Recommended name:
    Uncharacterized protein C1orf94

Gene names

Name:

C1orf94

Organism

Homo sapiens (Human) [Complete proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	408 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level.

Ontologies

Keywords
Coding sequence diversity	Polymorphism
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	protein binding Inferred from physical interaction. Source: IntAct
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
ATXN1	P54253	1	EBI-946029,EBI-930964

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 408	408	Uncharacterized protein C1orf94		PRO_0000280097
Regions
	Compositional bias	277 – 280	4	Poly-Pro
Natural variations
	Natural variant	45	1	Q → E: dbSNP rs1382602. Ref.3		VAR_031051
	Natural variant	112	1	D → E: dbSNP rs1414474. Ref.3		VAR_031052
	Natural variant	248	1	Y → H: dbSNP rs17556981.		VAR_050702

Sequences

	Sequence		Length	Mass (Da)
	Q6P1W5-1 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 5B1E356339E5941C	FASTA	408	44,902
	10 20 30 40 50 60 MPVISSRQDC DSATSTVTDI LCAAEVKSSK GTEDRGRILG DSNLQVSKLL SQFPLKSTET 70 80 90 100 110 120 SKVPDNKNVL DKTRVTKDFL QDNLFSGPGP KEPTGLSPFL LLPPRPPPAR PDKLPELPAQ 130 140 150 160 170 180 KRQLPVFAKI CSKPKADPAV ERHHLMEWSP GTKEPKKGQG SLFLSQWPQS QKDACGEEGC 190 200 210 220 230 240 CDAVGTASLT LPPKKPTCPA EKNLLYEFLG ATKNPSGQPR LRNKVEVDGP ELKFNAPVTV 250 260 270 280 290 300 ADKNNPKYTG NVFTPHFPTA MTSATLNQPL WLNLNYPPPP VFTNHSTFLQ YQGLYPQQAA 310 320 330 340 350 360 RMPYQQALHP QLGCYSQQVM PYNPQQMGQQ IFRSSYTPLL SYIPFVQPNY PYPQRTPPKM 370 380 390 400 SANPRDPPLM AGDGPQYLFP QGYGFGSTSG GPLMHSPYFS SSGNGINF

References

[1]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed: 14702039] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Caudate nucleus.
[2]	Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANTS GLU-45 AND GLU-112. Tissue: Muscle and Testis.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK123355 mRNA. Translation: BAG53893.1. CH471059 Genomic DNA. Translation: EAX07445.1. BC007637 mRNA. Translation: AAH07637.1. BC064845 mRNA. Translation: AAH64845.1.
IPI	IPI00645901.
RefSeq	NP_001128206.1. NP_116273.2.
UniGene	Hs.194610
3D structure databases
ModBase	Search...
Protein-protein interaction databases
IntAct	Q6P1W5. 6 interactions.
STRING	Q6P1W5.
Proteomic databases
PRIDE	Q6P1W5.
Genome annotation databases
Ensembl	ENST00000373374; ENSP00000362472; ENSG00000142698; Homo sapiens. [Genome view] ENST00000398041; ENSP00000381121; ENSG00000142698; Homo sapiens. [Genome view]
GeneID	84970.
KEGG	hsa:84970.
UCSC	uc001bxs.2. human.
Organism-specific databases
CTD	84970.
GeneCards	GC01P034405.
HGNC	HGNC:28250. C1orf94.
PharmGKB	PA142672478.
GenAtlas	Search...
Phylogenomic databases
eggNOG	prNOG12523.
HOGENOM	HBG506161.
HOVERGEN	Q6P1W5.
InParanoid	Q6P1W5.
PhylomeDB	Q6P1W5.
Gene expression databases
ArrayExpress	Q6P1W5.
Bgee	Q6P1W5.
CleanEx	HS_C1orf94.
Genevestigator	Q6P1W5.
Family and domain databases
ProtoNet	Search...
Other Resources
NextBio	75514.

Entry information

Entry name

CA094_HUMAN

Accession

Primary (citable) accession number: Q6P1W5
Secondary accession number(s): B3KVT1, Q96IC8

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 6, 2007
Last sequence update:	July 5, 2004
Last modified:	January 19, 2010
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.