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Protein
Submitted name:

PPM2C protein

Gene

PPM2C

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Cofactori

Mg2+SAAS annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphataseUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumSAAS annotation, Metal-bindingSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
PPM2C proteinImported
Gene namesi
Name:PPM2CImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA33607.

PTM / Processingi

Proteomic databases

PaxDbiQ6P1N1.
PRIDEiQ6P1N1.

Expressioni

Gene expression databases

BgeeiENSG00000164951.
GenevisibleiQ6P1N1. HS.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000379503.

Structurei

3D structure databases

ProteinModelPortaliQ6P1N1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini178 – 594417PPM-type phosphataseInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the PP2C family.UniRule annotation
Contains PPM-type phosphatase domain.SAAS annotation

Phylogenomic databases

eggNOGiKOG0700. Eukaryota.
COG0631. LUCA.
HOGENOMiHOG000220821.
HOVERGENiHBG008162.

Family and domain databases

Gene3Di3.60.40.10. 2 hits.
InterProiIPR015655. PP2C.
IPR000222. PP2C_BS.
IPR001932. PPM-type_phosphatase_dom.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 5 hits.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 3 hits.
PROSITEiPS01032. PPM_1. 1 hit.
PS51746. PPM_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q6P1N1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
GQAGGEGSRS GSCTGLRGKS AERWRRCRPL LVGKNRLVSC RARRMCVCPG
60 70 80 90 100
PRRIGIPVRS SSLPLFSDAM PAPTQLFFPL IRNCELSRIY GTACYCHHKH
110 120 130 140 150
LCCSSSYIPQ SRLRYTPHPA YATFCRPKEN WWQYTQGRRY ASTPQKFYLT
160 170 180 190 200
PPQVNSILKA NEYSFKVPEF DGKNVSSILG FDSNQLPANA PIEDRRSAAT
210 220 230 240 250
CLQTRGMLLG VFDGHAGCAC SQAVSERLFY YIAVSLLPHE TLLEIENAVE
260 270 280 290 300
SGRALLPILQ WHKHPNDYFS KEASKLYFNS LRTYWQELID LNTGESTDID
310 320 330 340 350
VKEALINAFK RLDNDISLEA QVGDPNSFLN YLVLRVAFSG ATACVAHVDG
360 370 380 390 400
VDLHVANTGD SRAMLGVQEE DGSWSAVTLS NDHNAQNERE LERLKLEHPK
410 420 430 440 450
SEAKSVVKQD RLLGLLMPFR AFGDVKFKWS IDLQKRVIES GPDQLNDNEY
460 470 480 490 500
TKFIPPNYHT PPYLTAEPEV TYHRLRPQDK FLVLATDGLW ETMHRQDVVR
510 520 530 540 550
IVGEYLTGMH HQQPIAVGGY KVTLGQMHGL LTERRTKMSS VFEDQNAATH
560 570 580 590 600
LIRHAVGNNE FGTVDHERLS KMLSLPEELA RMYRDDITII VVQFNSHVVG

AYQNQE
Length:606
Mass (Da):68,464
Last modified:July 5, 2004 - v1
Checksum:i86A58745E5DDFE64
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC064978 mRNA. Translation: AAH64978.1.
RefSeqiNP_001155252.1. NM_001161780.1.
UniGeneiHs.22265.

Genome annotation databases

GeneIDi54704.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC064978 mRNA. Translation: AAH64978.1.
RefSeqiNP_001155252.1. NM_001161780.1.
UniGeneiHs.22265.

3D structure databases

ProteinModelPortaliQ6P1N1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000379503.

Proteomic databases

PaxDbiQ6P1N1.
PRIDEiQ6P1N1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi54704.

Organism-specific databases

CTDi54704.
PharmGKBiPA33607.

Phylogenomic databases

eggNOGiKOG0700. Eukaryota.
COG0631. LUCA.
HOGENOMiHOG000220821.
HOVERGENiHBG008162.

Miscellaneous databases

ChiTaRSiPDP1. human.
GenomeRNAii54704.

Gene expression databases

BgeeiENSG00000164951.
GenevisibleiQ6P1N1. HS.

Family and domain databases

Gene3Di3.60.40.10. 2 hits.
InterProiIPR015655. PP2C.
IPR000222. PP2C_BS.
IPR001932. PPM-type_phosphatase_dom.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 5 hits.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 3 hits.
PROSITEiPS01032. PPM_1. 1 hit.
PS51746. PPM_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ6P1N1_HUMAN
AccessioniPrimary (citable) accession number: Q6P1N1
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: September 7, 2016
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.