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Q6P1M9

- ARMX5_HUMAN

UniProt

Q6P1M9 - ARMX5_HUMAN

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Protein

Armadillo repeat-containing X-linked protein 5

Gene

ARMCX5

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Armadillo repeat-containing X-linked protein 5
Gene namesi
Name:ARMCX5
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome X

Organism-specific databases

HGNCiHGNC:25772. ARMCX5.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134910322.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 558558Armadillo repeat-containing X-linked protein 5PRO_0000191371Add
BLAST

Proteomic databases

MaxQBiQ6P1M9.
PaxDbiQ6P1M9.
PRIDEiQ6P1M9.

PTM databases

PhosphoSiteiQ6P1M9.

Expressioni

Gene expression databases

BgeeiQ6P1M9.
CleanExiHS_ARMCX5.
ExpressionAtlasiQ6P1M9. baseline and differential.
GenevestigatoriQ6P1M9.

Organism-specific databases

HPAiHPA000996.

Interactioni

Protein-protein interaction databases

BioGridi122333. 2 interactions.
STRINGi9606.ENSP00000246174.

Structurei

3D structure databases

ProteinModelPortaliQ6P1M9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati300 – 33940ARM 1Add
BLAST
Repeati422 – 46140ARM 2Add
BLAST
Repeati463 – 50341ARM 3Add
BLAST

Sequence similaritiesi

Contains 3 ARM repeats.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiNOG46730.
GeneTreeiENSGT00550000074488.
HOGENOMiHOG000231408.
HOVERGENiHBG080263.
InParanoidiQ6P1M9.
OMAiPSVGSWF.
OrthoDBiEOG70PBZ0.
PhylomeDBiQ6P1M9.
TreeFamiTF335652.

Family and domain databases

Gene3Di1.25.10.10. 1 hit.
InterProiIPR011989. ARM-like.
IPR006911. ARM-rpt_dom.
IPR016024. ARM-type_fold.
[Graphical view]
PfamiPF04826. Arm_2. 1 hit.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6P1M9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVDSGTEARA RGKAEAGLQD GISGPATARV NGKTQAEAVA EAELKTESVT
60 70 80 90 100
QAKAGDGAMT RTHTVTYREA MAVTREVIKV EDTTKTRVMV ETKTKPLAER
110 120 130 140 150
SIVPQTKSKA MPMSRVSTVT KSEVKVVAVI EANIRSYAKS HDKANTGSRP
160 170 180 190 200
DRREETSIGM KSSDEDEENI CSWFWTGEEP SVGSWFWPEE ETSLQVYKPL
210 220 230 240 250
PKIQEKPKPT HKPTLTIKQK VIAWSRARYI VLVPVEGGEQ SLPPEGNWTL
260 270 280 290 300
VETLIETPLG IRPLTKIPPY HGPYYQTLAE IKKQIRQREK YGPNPKACHC
310 320 330 340 350
KSRGFSLEPK EFDKLVALLK LTKDPFIHEI ATMIMGISPA YPFTQDIIHD
360 370 380 390 400
VGITVMIENL VNNPNVKEHP GALSMVDDSS ESSEEPKSGE SYIHQVCKGI
410 420 430 440 450
ISCPLNSPVQ LAGLKLLGHL SIKFEDHYVI TSYIPDFLTL LNKGSVKTKF
460 470 480 490 500
YVLKVFSCLS KNHANTRELI SAKVLSSLVA PFNKNESKAN ILNIIEIFEN
510 520 530 540 550
INFQFKTKAK LFTKEKFTKS ELISIFQEAK QFGQKLQDLA EHSDPEVRDK

VIRLILKL
Length:558
Mass (Da):62,346
Last modified:July 5, 2004 - v1
Checksum:i5783D6A62445BF5C
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti337 – 3371I → V in BAB14367. (PubMed:17974005)Curated
Sequence conflicti376 – 3761V → A in CAH18306. (PubMed:14702039)Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK023031 mRNA. Translation: BAB14367.1.
AK096692 mRNA. Translation: BAG53350.1.
CR749476 mRNA. Translation: CAH18306.1.
AL035551 Genomic DNA. Translation: CAI42194.1.
CH471190 Genomic DNA. Translation: EAW54733.1.
CH471190 Genomic DNA. Translation: EAW54734.1.
BC000792 mRNA. Translation: AAH00792.1.
BC058904 mRNA. Translation: AAH58904.1.
BC064983 mRNA. Translation: AAH64983.1.
CCDSiCCDS14500.1.
RefSeqiNP_001161950.1. NM_001168478.1.
NP_001161951.1. NM_001168479.1.
NP_001161952.1. NM_001168480.1.
NP_001161954.1. NM_001168482.1.
NP_001161957.1. NM_001168485.1.
NP_073749.2. NM_022838.3.
UniGeneiHs.522729.

Genome annotation databases

EnsembliENST00000246174; ENSP00000246174; ENSG00000125962.
ENST00000372742; ENSP00000361827; ENSG00000125962.
ENST00000604957; ENSP00000474720; ENSG00000125962.
GeneIDi64860.
KEGGihsa:64860.
UCSCiuc004ejg.3. human.

Polymorphism databases

DMDMi74749066.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK023031 mRNA. Translation: BAB14367.1 .
AK096692 mRNA. Translation: BAG53350.1 .
CR749476 mRNA. Translation: CAH18306.1 .
AL035551 Genomic DNA. Translation: CAI42194.1 .
CH471190 Genomic DNA. Translation: EAW54733.1 .
CH471190 Genomic DNA. Translation: EAW54734.1 .
BC000792 mRNA. Translation: AAH00792.1 .
BC058904 mRNA. Translation: AAH58904.1 .
BC064983 mRNA. Translation: AAH64983.1 .
CCDSi CCDS14500.1.
RefSeqi NP_001161950.1. NM_001168478.1.
NP_001161951.1. NM_001168479.1.
NP_001161952.1. NM_001168480.1.
NP_001161954.1. NM_001168482.1.
NP_001161957.1. NM_001168485.1.
NP_073749.2. NM_022838.3.
UniGenei Hs.522729.

3D structure databases

ProteinModelPortali Q6P1M9.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 122333. 2 interactions.
STRINGi 9606.ENSP00000246174.

PTM databases

PhosphoSitei Q6P1M9.

Polymorphism databases

DMDMi 74749066.

Proteomic databases

MaxQBi Q6P1M9.
PaxDbi Q6P1M9.
PRIDEi Q6P1M9.

Protocols and materials databases

DNASUi 64860.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000246174 ; ENSP00000246174 ; ENSG00000125962 .
ENST00000372742 ; ENSP00000361827 ; ENSG00000125962 .
ENST00000604957 ; ENSP00000474720 ; ENSG00000125962 .
GeneIDi 64860.
KEGGi hsa:64860.
UCSCi uc004ejg.3. human.

Organism-specific databases

CTDi 64860.
GeneCardsi GC0XP101854.
H-InvDB HIX0016938.
HGNCi HGNC:25772. ARMCX5.
HPAi HPA000996.
neXtProti NX_Q6P1M9.
PharmGKBi PA134910322.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG46730.
GeneTreei ENSGT00550000074488.
HOGENOMi HOG000231408.
HOVERGENi HBG080263.
InParanoidi Q6P1M9.
OMAi PSVGSWF.
OrthoDBi EOG70PBZ0.
PhylomeDBi Q6P1M9.
TreeFami TF335652.

Miscellaneous databases

GenomeRNAii 64860.
NextBioi 67015.
PROi Q6P1M9.

Gene expression databases

Bgeei Q6P1M9.
CleanExi HS_ARMCX5.
ExpressionAtlasi Q6P1M9. baseline and differential.
Genevestigatori Q6P1M9.

Family and domain databases

Gene3Di 1.25.10.10. 1 hit.
InterProi IPR011989. ARM-like.
IPR006911. ARM-rpt_dom.
IPR016024. ARM-type_fold.
[Graphical view ]
Pfami PF04826. Arm_2. 1 hit.
[Graphical view ]
SUPFAMi SSF48371. SSF48371. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Esophageal carcinoma.
  3. "The DNA sequence of the human X chromosome."
    Ross M.T., Grafham D.V., Coffey A.J., Scherer S., McLay K., Muzny D., Platzer M., Howell G.R., Burrows C., Bird C.P., Frankish A., Lovell F.L., Howe K.L., Ashurst J.L., Fulton R.S., Sudbrak R., Wen G., Jones M.C.
    , Hurles M.E., Andrews T.D., Scott C.E., Searle S., Ramser J., Whittaker A., Deadman R., Carter N.P., Hunt S.E., Chen R., Cree A., Gunaratne P., Havlak P., Hodgson A., Metzker M.L., Richards S., Scott G., Steffen D., Sodergren E., Wheeler D.A., Worley K.C., Ainscough R., Ambrose K.D., Ansari-Lari M.A., Aradhya S., Ashwell R.I., Babbage A.K., Bagguley C.L., Ballabio A., Banerjee R., Barker G.E., Barlow K.F., Barrett I.P., Bates K.N., Beare D.M., Beasley H., Beasley O., Beck A., Bethel G., Blechschmidt K., Brady N., Bray-Allen S., Bridgeman A.M., Brown A.J., Brown M.J., Bonnin D., Bruford E.A., Buhay C., Burch P., Burford D., Burgess J., Burrill W., Burton J., Bye J.M., Carder C., Carrel L., Chako J., Chapman J.C., Chavez D., Chen E., Chen G., Chen Y., Chen Z., Chinault C., Ciccodicola A., Clark S.Y., Clarke G., Clee C.M., Clegg S., Clerc-Blankenburg K., Clifford K., Cobley V., Cole C.G., Conquer J.S., Corby N., Connor R.E., David R., Davies J., Davis C., Davis J., Delgado O., Deshazo D., Dhami P., Ding Y., Dinh H., Dodsworth S., Draper H., Dugan-Rocha S., Dunham A., Dunn M., Durbin K.J., Dutta I., Eades T., Ellwood M., Emery-Cohen A., Errington H., Evans K.L., Faulkner L., Francis F., Frankland J., Fraser A.E., Galgoczy P., Gilbert J., Gill R., Gloeckner G., Gregory S.G., Gribble S., Griffiths C., Grocock R., Gu Y., Gwilliam R., Hamilton C., Hart E.A., Hawes A., Heath P.D., Heitmann K., Hennig S., Hernandez J., Hinzmann B., Ho S., Hoffs M., Howden P.J., Huckle E.J., Hume J., Hunt P.J., Hunt A.R., Isherwood J., Jacob L., Johnson D., Jones S., de Jong P.J., Joseph S.S., Keenan S., Kelly S., Kershaw J.K., Khan Z., Kioschis P., Klages S., Knights A.J., Kosiura A., Kovar-Smith C., Laird G.K., Langford C., Lawlor S., Leversha M., Lewis L., Liu W., Lloyd C., Lloyd D.M., Loulseged H., Loveland J.E., Lovell J.D., Lozado R., Lu J., Lyne R., Ma J., Maheshwari M., Matthews L.H., McDowall J., McLaren S., McMurray A., Meidl P., Meitinger T., Milne S., Miner G., Mistry S.L., Morgan M., Morris S., Mueller I., Mullikin J.C., Nguyen N., Nordsiek G., Nyakatura G., O'dell C.N., Okwuonu G., Palmer S., Pandian R., Parker D., Parrish J., Pasternak S., Patel D., Pearce A.V., Pearson D.M., Pelan S.E., Perez L., Porter K.M., Ramsey Y., Reichwald K., Rhodes S., Ridler K.A., Schlessinger D., Schueler M.G., Sehra H.K., Shaw-Smith C., Shen H., Sheridan E.M., Shownkeen R., Skuce C.D., Smith M.L., Sotheran E.C., Steingruber H.E., Steward C.A., Storey R., Swann R.M., Swarbreck D., Tabor P.E., Taudien S., Taylor T., Teague B., Thomas K., Thorpe A., Timms K., Tracey A., Trevanion S., Tromans A.C., d'Urso M., Verduzco D., Villasana D., Waldron L., Wall M., Wang Q., Warren J., Warry G.L., Wei X., West A., Whitehead S.L., Whiteley M.N., Wilkinson J.E., Willey D.L., Williams G., Williams L., Williamson A., Williamson H., Wilming L., Woodmansey R.L., Wray P.W., Yen J., Zhang J., Zhou J., Zoghbi H., Zorilla S., Buck D., Reinhardt R., Poustka A., Rosenthal A., Lehrach H., Meindl A., Minx P.J., Hillier L.W., Willard H.F., Wilson R.K., Waterston R.H., Rice C.M., Vaudin M., Coulson A., Nelson D.L., Weinstock G., Sulston J.E., Durbin R.M., Hubbard T., Gibbs R.A., Beck S., Rogers J., Bentley D.R.
    Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Muscle, Placenta and Uterus.

Entry informationi

Entry nameiARMX5_HUMAN
AccessioniPrimary (citable) accession number: Q6P1M9
Secondary accession number(s): B3KU88
, D3DX99, Q68DB4, Q9BVZ3, Q9H969
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: July 5, 2004
Last modified: October 29, 2014
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3