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Q6P1M9

- ARMX5_HUMAN

UniProt

Q6P1M9 - ARMX5_HUMAN

Protein

Armadillo repeat-containing X-linked protein 5

Gene

ARMCX5

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 91 (01 Oct 2014)
      Sequence version 1 (05 Jul 2004)
      Previous versions | rss
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    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Armadillo repeat-containing X-linked protein 5
    Gene namesi
    Name:ARMCX5
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome X

    Organism-specific databases

    HGNCiHGNC:25772. ARMCX5.

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA134910322.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 558558Armadillo repeat-containing X-linked protein 5PRO_0000191371Add
    BLAST

    Proteomic databases

    MaxQBiQ6P1M9.
    PaxDbiQ6P1M9.
    PRIDEiQ6P1M9.

    PTM databases

    PhosphoSiteiQ6P1M9.

    Expressioni

    Gene expression databases

    BgeeiQ6P1M9.
    CleanExiHS_ARMCX5.
    GenevestigatoriQ6P1M9.

    Organism-specific databases

    HPAiHPA000996.

    Interactioni

    Protein-protein interaction databases

    BioGridi122333. 2 interactions.
    STRINGi9606.ENSP00000246174.

    Structurei

    3D structure databases

    ProteinModelPortaliQ6P1M9.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Repeati300 – 33940ARM 1Add
    BLAST
    Repeati422 – 46140ARM 2Add
    BLAST
    Repeati463 – 50341ARM 3Add
    BLAST

    Sequence similaritiesi

    Contains 3 ARM repeats.Curated

    Keywords - Domaini

    Repeat

    Phylogenomic databases

    eggNOGiNOG46730.
    HOGENOMiHOG000231408.
    HOVERGENiHBG080263.
    InParanoidiQ6P1M9.
    OMAiPSVGSWF.
    OrthoDBiEOG70PBZ0.
    PhylomeDBiQ6P1M9.
    TreeFamiTF335652.

    Family and domain databases

    Gene3Di1.25.10.10. 1 hit.
    InterProiIPR011989. ARM-like.
    IPR006911. ARM-rpt_dom.
    IPR016024. ARM-type_fold.
    [Graphical view]
    PfamiPF04826. Arm_2. 1 hit.
    [Graphical view]
    SUPFAMiSSF48371. SSF48371. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q6P1M9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MVDSGTEARA RGKAEAGLQD GISGPATARV NGKTQAEAVA EAELKTESVT    50
    QAKAGDGAMT RTHTVTYREA MAVTREVIKV EDTTKTRVMV ETKTKPLAER 100
    SIVPQTKSKA MPMSRVSTVT KSEVKVVAVI EANIRSYAKS HDKANTGSRP 150
    DRREETSIGM KSSDEDEENI CSWFWTGEEP SVGSWFWPEE ETSLQVYKPL 200
    PKIQEKPKPT HKPTLTIKQK VIAWSRARYI VLVPVEGGEQ SLPPEGNWTL 250
    VETLIETPLG IRPLTKIPPY HGPYYQTLAE IKKQIRQREK YGPNPKACHC 300
    KSRGFSLEPK EFDKLVALLK LTKDPFIHEI ATMIMGISPA YPFTQDIIHD 350
    VGITVMIENL VNNPNVKEHP GALSMVDDSS ESSEEPKSGE SYIHQVCKGI 400
    ISCPLNSPVQ LAGLKLLGHL SIKFEDHYVI TSYIPDFLTL LNKGSVKTKF 450
    YVLKVFSCLS KNHANTRELI SAKVLSSLVA PFNKNESKAN ILNIIEIFEN 500
    INFQFKTKAK LFTKEKFTKS ELISIFQEAK QFGQKLQDLA EHSDPEVRDK 550
    VIRLILKL 558
    Length:558
    Mass (Da):62,346
    Last modified:July 5, 2004 - v1
    Checksum:i5783D6A62445BF5C
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti337 – 3371I → V in BAB14367. (PubMed:17974005)Curated
    Sequence conflicti376 – 3761V → A in CAH18306. (PubMed:14702039)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK023031 mRNA. Translation: BAB14367.1.
    AK096692 mRNA. Translation: BAG53350.1.
    CR749476 mRNA. Translation: CAH18306.1.
    AL035551 Genomic DNA. Translation: CAI42194.1.
    CH471190 Genomic DNA. Translation: EAW54733.1.
    CH471190 Genomic DNA. Translation: EAW54734.1.
    BC000792 mRNA. Translation: AAH00792.1.
    BC058904 mRNA. Translation: AAH58904.1.
    BC064983 mRNA. Translation: AAH64983.1.
    CCDSiCCDS14500.1.
    RefSeqiNP_001161950.1. NM_001168478.1.
    NP_001161951.1. NM_001168479.1.
    NP_001161952.1. NM_001168480.1.
    NP_001161954.1. NM_001168482.1.
    NP_001161957.1. NM_001168485.1.
    NP_073749.2. NM_022838.3.
    UniGeneiHs.522729.

    Genome annotation databases

    EnsembliENST00000246174; ENSP00000246174; ENSG00000125962.
    ENST00000372742; ENSP00000361827; ENSG00000125962.
    ENST00000604957; ENSP00000474720; ENSG00000125962.
    GeneIDi64860.
    KEGGihsa:64860.
    UCSCiuc004ejg.3. human.

    Polymorphism databases

    DMDMi74749066.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK023031 mRNA. Translation: BAB14367.1 .
    AK096692 mRNA. Translation: BAG53350.1 .
    CR749476 mRNA. Translation: CAH18306.1 .
    AL035551 Genomic DNA. Translation: CAI42194.1 .
    CH471190 Genomic DNA. Translation: EAW54733.1 .
    CH471190 Genomic DNA. Translation: EAW54734.1 .
    BC000792 mRNA. Translation: AAH00792.1 .
    BC058904 mRNA. Translation: AAH58904.1 .
    BC064983 mRNA. Translation: AAH64983.1 .
    CCDSi CCDS14500.1.
    RefSeqi NP_001161950.1. NM_001168478.1.
    NP_001161951.1. NM_001168479.1.
    NP_001161952.1. NM_001168480.1.
    NP_001161954.1. NM_001168482.1.
    NP_001161957.1. NM_001168485.1.
    NP_073749.2. NM_022838.3.
    UniGenei Hs.522729.

    3D structure databases

    ProteinModelPortali Q6P1M9.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 122333. 2 interactions.
    STRINGi 9606.ENSP00000246174.

    PTM databases

    PhosphoSitei Q6P1M9.

    Polymorphism databases

    DMDMi 74749066.

    Proteomic databases

    MaxQBi Q6P1M9.
    PaxDbi Q6P1M9.
    PRIDEi Q6P1M9.

    Protocols and materials databases

    DNASUi 64860.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000246174 ; ENSP00000246174 ; ENSG00000125962 .
    ENST00000372742 ; ENSP00000361827 ; ENSG00000125962 .
    ENST00000604957 ; ENSP00000474720 ; ENSG00000125962 .
    GeneIDi 64860.
    KEGGi hsa:64860.
    UCSCi uc004ejg.3. human.

    Organism-specific databases

    CTDi 64860.
    GeneCardsi GC0XP101854.
    H-InvDB HIX0016938.
    HGNCi HGNC:25772. ARMCX5.
    HPAi HPA000996.
    neXtProti NX_Q6P1M9.
    PharmGKBi PA134910322.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG46730.
    HOGENOMi HOG000231408.
    HOVERGENi HBG080263.
    InParanoidi Q6P1M9.
    OMAi PSVGSWF.
    OrthoDBi EOG70PBZ0.
    PhylomeDBi Q6P1M9.
    TreeFami TF335652.

    Miscellaneous databases

    GenomeRNAii 64860.
    NextBioi 67015.
    PROi Q6P1M9.

    Gene expression databases

    Bgeei Q6P1M9.
    CleanExi HS_ARMCX5.
    Genevestigatori Q6P1M9.

    Family and domain databases

    Gene3Di 1.25.10.10. 1 hit.
    InterProi IPR011989. ARM-like.
    IPR006911. ARM-rpt_dom.
    IPR016024. ARM-type_fold.
    [Graphical view ]
    Pfami PF04826. Arm_2. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48371. SSF48371. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Esophageal carcinoma.
    3. "The DNA sequence of the human X chromosome."
      Ross M.T., Grafham D.V., Coffey A.J., Scherer S., McLay K., Muzny D., Platzer M., Howell G.R., Burrows C., Bird C.P., Frankish A., Lovell F.L., Howe K.L., Ashurst J.L., Fulton R.S., Sudbrak R., Wen G., Jones M.C.
      , Hurles M.E., Andrews T.D., Scott C.E., Searle S., Ramser J., Whittaker A., Deadman R., Carter N.P., Hunt S.E., Chen R., Cree A., Gunaratne P., Havlak P., Hodgson A., Metzker M.L., Richards S., Scott G., Steffen D., Sodergren E., Wheeler D.A., Worley K.C., Ainscough R., Ambrose K.D., Ansari-Lari M.A., Aradhya S., Ashwell R.I., Babbage A.K., Bagguley C.L., Ballabio A., Banerjee R., Barker G.E., Barlow K.F., Barrett I.P., Bates K.N., Beare D.M., Beasley H., Beasley O., Beck A., Bethel G., Blechschmidt K., Brady N., Bray-Allen S., Bridgeman A.M., Brown A.J., Brown M.J., Bonnin D., Bruford E.A., Buhay C., Burch P., Burford D., Burgess J., Burrill W., Burton J., Bye J.M., Carder C., Carrel L., Chako J., Chapman J.C., Chavez D., Chen E., Chen G., Chen Y., Chen Z., Chinault C., Ciccodicola A., Clark S.Y., Clarke G., Clee C.M., Clegg S., Clerc-Blankenburg K., Clifford K., Cobley V., Cole C.G., Conquer J.S., Corby N., Connor R.E., David R., Davies J., Davis C., Davis J., Delgado O., Deshazo D., Dhami P., Ding Y., Dinh H., Dodsworth S., Draper H., Dugan-Rocha S., Dunham A., Dunn M., Durbin K.J., Dutta I., Eades T., Ellwood M., Emery-Cohen A., Errington H., Evans K.L., Faulkner L., Francis F., Frankland J., Fraser A.E., Galgoczy P., Gilbert J., Gill R., Gloeckner G., Gregory S.G., Gribble S., Griffiths C., Grocock R., Gu Y., Gwilliam R., Hamilton C., Hart E.A., Hawes A., Heath P.D., Heitmann K., Hennig S., Hernandez J., Hinzmann B., Ho S., Hoffs M., Howden P.J., Huckle E.J., Hume J., Hunt P.J., Hunt A.R., Isherwood J., Jacob L., Johnson D., Jones S., de Jong P.J., Joseph S.S., Keenan S., Kelly S., Kershaw J.K., Khan Z., Kioschis P., Klages S., Knights A.J., Kosiura A., Kovar-Smith C., Laird G.K., Langford C., Lawlor S., Leversha M., Lewis L., Liu W., Lloyd C., Lloyd D.M., Loulseged H., Loveland J.E., Lovell J.D., Lozado R., Lu J., Lyne R., Ma J., Maheshwari M., Matthews L.H., McDowall J., McLaren S., McMurray A., Meidl P., Meitinger T., Milne S., Miner G., Mistry S.L., Morgan M., Morris S., Mueller I., Mullikin J.C., Nguyen N., Nordsiek G., Nyakatura G., O'dell C.N., Okwuonu G., Palmer S., Pandian R., Parker D., Parrish J., Pasternak S., Patel D., Pearce A.V., Pearson D.M., Pelan S.E., Perez L., Porter K.M., Ramsey Y., Reichwald K., Rhodes S., Ridler K.A., Schlessinger D., Schueler M.G., Sehra H.K., Shaw-Smith C., Shen H., Sheridan E.M., Shownkeen R., Skuce C.D., Smith M.L., Sotheran E.C., Steingruber H.E., Steward C.A., Storey R., Swann R.M., Swarbreck D., Tabor P.E., Taudien S., Taylor T., Teague B., Thomas K., Thorpe A., Timms K., Tracey A., Trevanion S., Tromans A.C., d'Urso M., Verduzco D., Villasana D., Waldron L., Wall M., Wang Q., Warren J., Warry G.L., Wei X., West A., Whitehead S.L., Whiteley M.N., Wilkinson J.E., Willey D.L., Williams G., Williams L., Williamson A., Williamson H., Wilming L., Woodmansey R.L., Wray P.W., Yen J., Zhang J., Zhou J., Zoghbi H., Zorilla S., Buck D., Reinhardt R., Poustka A., Rosenthal A., Lehrach H., Meindl A., Minx P.J., Hillier L.W., Willard H.F., Wilson R.K., Waterston R.H., Rice C.M., Vaudin M., Coulson A., Nelson D.L., Weinstock G., Sulston J.E., Durbin R.M., Hubbard T., Gibbs R.A., Beck S., Rogers J., Bentley D.R.
      Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Muscle, Placenta and Uterus.

    Entry informationi

    Entry nameiARMX5_HUMAN
    AccessioniPrimary (citable) accession number: Q6P1M9
    Secondary accession number(s): B3KU88
    , D3DX99, Q68DB4, Q9BVZ3, Q9H969
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 20, 2005
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 91 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome X
      Human chromosome X: entries, gene names and cross-references to MIM
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3