Q6P158 (DHX57_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative ATP-dependent RNA helicase DHX57
EC=3.6.4.13

Alternative name(s):
DEAH box protein 57

Gene names

Name:

DHX57

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	1386 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Probable ATP-binding RNA helicase.
Catalytic activity	ATP + H2O = ADP + phosphate.
Sequence similarities	Belongs to the DEAD box helicase family. DEAH subfamily. Contains 1 C3H1-type zinc finger. Contains 1 helicase ATP-binding domain. Contains 1 helicase C-terminal domain. Contains 1 UBA domain.
Sequence caution	The sequence AAM73547.1 differs from that shown. Reason: Erroneous initiation. The sequence AAY24256.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
Coding sequence diversity	Alternative splicing Polymorphism
Domain	Coiled coil Zinc-finger
Ligand	ATP-binding Metal-binding Nucleotide-binding Zinc
Molecular function	Helicase Hydrolase
PTM	Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ATP-dependent helicase activity Inferred from electronic annotation. Source: InterPro nucleic acid binding Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Alternative products

This entry describes 3 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q6P158-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q6P158-2)

The sequence of this isoform differs from the canonical sequence as follows:
     636-658: SSATRLLYCTTGVLLRRLEGDTA → VCMLCLFPGNRNLWFLGIKSFGG
     659-1386: Missing.

Note: No experimental confirmation available.

Isoform 3 (identifier: Q6P158-3)

The sequence of this isoform differs from the canonical sequence as follows:
     1-102: Missing.
     530-535: ASRQFQ → VLNSHM
     536-1386: Missing.

Note: No experimental confirmation available.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1386	1386	Putative ATP-dependent RNA helicase DHX57		PRO_0000233151
Regions
	Domain	180 – 220	41	UBA
	Domain	554 – 721	168	Helicase ATP-binding
	Domain	830 – 1010	181	Helicase C-terminal
	Zinc finger	299 – 326	28	C3H1-type
	Nucleotide binding	567 – 574	8	ATP By similarity
	Coiled coil	101 – 125	25	Potential
	Motif	668 – 671	4	DEVH box
	Compositional bias	9 – 49	41	Gly-rich
Amino acid modifications
	Modified residue	127	1	Phosphoserine Ref.5 Ref.7 Ref.9
	Modified residue	475	1	Phosphoserine Ref.6
	Modified residue	477	1	Phosphoserine Ref.6
	Modified residue	480	1	Phosphoserine Ref.5 Ref.6
Natural variations
	Alternative sequence	1 – 102	102	Missing in isoform 3.		VSP_018056
	Alternative sequence	530 – 535	6	ASRQFQ → VLNSHM in isoform 3.		VSP_018057
	Alternative sequence	536 – 1386	851	Missing in isoform 3.		VSP_018058
	Alternative sequence	636 – 658	23	SSATR…EGDTA → VCMLCLFPGNRNLWFLGIKS FGG in isoform 2.		VSP_018059
	Alternative sequence	659 – 1386	728	Missing in isoform 2.		VSP_018060
	Natural variant	410	1	S → F. Corresponds to variant rs11893062 [ dbSNP | Ensembl ].		VAR_052190
	Natural variant	433	1	S → G. Corresponds to variant rs35371077 [ dbSNP | Ensembl ].		VAR_033861
	Natural variant	587	1	N → S. Ref.3 Ref.4 Corresponds to variant rs7598922 [ dbSNP | Ensembl ].		VAR_052191
Experimental info
	Sequence conflict	474	1	A → T in BAB71479. Ref.1
	Sequence conflict	976	1	L → V in AAM73547. Ref.4

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified May 2, 2006. Version 2. Checksum: FFF62BD4BF4C1F4D	FASTA	1,386	155,604
	10 20 30 40 50 60 MSSSVRRKGK PGKGGGKGSS RGGRGGRSHA SKSHGSGGGG GGGGGGGGGN RKASSRIWDD 70 80 90 100 110 120 GDDFCIFSES RRPSRPSNSN ISKGESRPKW KPKAKVPLQT LHMTSENQEK VKALLRDLQE 130 140 150 160 170 180 QDADAGSERG LSGEEEDDEP DCCNDERYWP AGQEPSLVPD LDPLEYAGLA SVEPYVPEFT 190 200 210 220 230 240 VSPFAVQKLS RYGFNTERCQ AVLRMCDGDV GASLEHLLTQ CFSETFGERM KISEAVNQIS 250 260 270 280 290 300 LDECMEQRQE EAFALKSICG EKFIERIQNR VWTIGLELEY LTSRFRKSKP KESTKNVQEN 310 320 330 340 350 360 SLEICKFYLK GNCKFGSKCR FKHEVPPNQI VGRIERSVDD SHLNAIEDAS FLYELEIRFS 370 380 390 400 410 420 KDHKYPYQAP LVAFYSTNEN LPLACRLHIS EFLYDKALTF AETSEPVVYS LITLLEEESE 430 440 450 460 470 480 IVKLLTNTHH KYSDPPVNFL PVPSRTRINN PACHKTVIPN NSFVSNQIPE VEKASESEES 490 500 510 520 530 540 DEDDGPAPVI VENESYVNLK KKISKRYDWQ AKSVHAENGK ICKQFRMKQA SRQFQSILQE 550 560 570 580 590 600 RQSLPAWEER ETILNLLRKH QVVVISGMTG CGKTTQIPQF ILDDSLNGPP EKVANIICTQ 610 620 630 640 650 660 PRRISAISVA ERVAKERAER VGLTVGYQIR LESVKSSATR LLYCTTGVLL RRLEGDTALQ 670 680 690 700 710 720 GVSHIIVDEV HERTEESDFL LLVLKDIVSQ RPGLQVILMS ATLNAELFSD YFNSCPVITI 730 740 750 760 770 780 PGRTFPVDQF FLEDAIAVTR YVLQDGSPYM RSMKQISKEK LKARRNRTAF EEVEEDLRLS 790 800 810 820 830 840 LHLQDQDSVK DAVPDQQLDF KQLLARYKGV SKSVIKTMSI MDFEKVNLEL IEALLEWIVD 850 860 870 880 890 900 GKHSYPPGAI LVFLPGLAEI KMLYEQLQSN SLFNNRRSNR CVIHPLHSSL SSEEQQAVFV 910 920 930 940 950 960 KPPAGVTKII ISTNIAETSI TIDDVVYVID SGKMKEKRYD ASKGMESLED TFVSQANALQ 970 980 990 1000 1010 1020 RKGRAGRVAS GVCFHLFTSH HYNHQLLKQQ LPEIQRVPLE QLCLRIKILE MFSAHNLQSV 1030 1040 1050 1060 1070 1080 FSRLIEPPHT DSLRASKIRL RDLGALTPDE RLTPLGYHLA SLPVDVRIGK LMLFGSIFRC 1090 1100 1110 1120 1130 1140 LDPALTIAAS LAFKSPFVSP WDKKEEANQK KLEFAFANSD YLALLQAYKG WQLSTKEGVR 1150 1160 1170 1180 1190 1200 ASYNYCRQNF LSGRVLQEMA SLKRQFTELL SDIGFAREGL RAREIEKRAQ GGDGVLDATG 1210 1220 1230 1240 1250 1260 EEANSNAENP KLISAMLCAA LYPNVVQVKS PEGKFQKTST GAVRMQPKSA ELKFVTKNDG 1270 1280 1290 1300 1310 1320 YVHIHPSSVN YQVRHFDSPY LLYHEKIKTS RVFIRDCSMV SVYPLVLFGG GQVNVQLQRG 1330 1340 1350 1360 1370 1380 EFVVSLDDGW IRFVAASHQV AELVKELRCE LDQLLQDKIK NPSIDLCTCP RGSRIISTIV KLVTTQ
	Isoform 2 [UniParc]. Checksum: 570E49695D5B05A3	FASTA	658	73,602
	10 20 30 40 50 60 MSSSVRRKGK PGKGGGKGSS RGGRGGRSHA SKSHGSGGGG GGGGGGGGGN RKASSRIWDD 70 80 90 100 110 120 GDDFCIFSES RRPSRPSNSN ISKGESRPKW KPKAKVPLQT LHMTSENQEK VKALLRDLQE 130 140 150 160 170 180 QDADAGSERG LSGEEEDDEP DCCNDERYWP AGQEPSLVPD LDPLEYAGLA SVEPYVPEFT 190 200 210 220 230 240 VSPFAVQKLS RYGFNTERCQ AVLRMCDGDV GASLEHLLTQ CFSETFGERM KISEAVNQIS 250 260 270 280 290 300 LDECMEQRQE EAFALKSICG EKFIERIQNR VWTIGLELEY LTSRFRKSKP KESTKNVQEN 310 320 330 340 350 360 SLEICKFYLK GNCKFGSKCR FKHEVPPNQI VGRIERSVDD SHLNAIEDAS FLYELEIRFS 370 380 390 400 410 420 KDHKYPYQAP LVAFYSTNEN LPLACRLHIS EFLYDKALTF AETSEPVVYS LITLLEEESE 430 440 450 460 470 480 IVKLLTNTHH KYSDPPVNFL PVPSRTRINN PACHKTVIPN NSFVSNQIPE VEKASESEES 490 500 510 520 530 540 DEDDGPAPVI VENESYVNLK KKISKRYDWQ AKSVHAENGK ICKQFRMKQA SRQFQSILQE 550 560 570 580 590 600 RQSLPAWEER ETILNLLRKH QVVVISGMTG CGKTTQIPQF ILDDSLNGPP EKVANIICTQ 610 620 630 640 650 PRRISAISVA ERVAKERAER VGLTVGYQIR LESVKVCMLC LFPGNRNLWF LGIKSFGG
	Isoform 3 [UniParc]. Checksum: 1B83D88C94570046	FASTA	433	49,508
	10 20 30 40 50 60 MTSENQEKVK ALLRDLQEQD ADAGSERGLS GEEEDDEPDC CNDERYWPAG QEPSLVPDLD 70 80 90 100 110 120 PLEYAGLASV EPYVPEFTVS PFAVQKLSRY GFNTERCQAV LRMCDGDVGA SLEHLLTQCF 130 140 150 160 170 180 SETFGERMKI SEAVNQISLD ECMEQRQEEA FALKSICGEK FIERIQNRVW TIGLELEYLT 190 200 210 220 230 240 SRFRKSKPKE STKNVQENSL EICKFYLKGN CKFGSKCRFK HEVPPNQIVG RIERSVDDSH 250 260 270 280 290 300 LNAIEDASFL YELEIRFSKD HKYPYQAPLV AFYSTNENLP LACRLHISEF LYDKALTFAE 310 320 330 340 350 360 TSEPVVYSLI TLLEEESEIV KLLTNTHHKY SDPPVNFLPV PSRTRINNPA CHKTVIPNNS 370 380 390 400 410 420 FVSNQIPEVE KASESEESDE DDGPAPVIVE NESYVNLKKK ISKRYDWQAK SVHAENGKIC 430 KQFRMKQVLN SHM

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3). Tissue: Testis.
[2]	"Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H. , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K. Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2), VARIANT SER-587. Tissue: Skin.
[4]	"Molecular cloning of a new member of DEAH-box RNA/DNA helicase gene family." Lin S., Ying K., Wang Z., Xie Y., Mao Y. Submitted (JUN-2000) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 405-1386 (ISOFORM 1), VARIANT SER-587. Tissue: Brain.
[5]	"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M. Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-127 AND SER-480, MASS SPECTROMETRY. Tissue: Cervix carcinoma.
[6]	"A quantitative atlas of mitotic phosphorylation." Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., Elledge S.J., Gygi S.P. Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-475; SER-477 AND SER-480, MASS SPECTROMETRY. Tissue: Cervix carcinoma.
[7]	"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis." Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M. Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-127, MASS SPECTROMETRY. Tissue: Cervix carcinoma.
[8]	"Initial characterization of the human central proteome." Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J. BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[9]	"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation." Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B. Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-127, MASS SPECTROMETRY.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK057423 mRNA. Translation: BAB71479.1. AC018693 Genomic DNA. Translation: AAY24256.1. Sequence problems. BC053623 mRNA. Translation: AAH53623.1. BC060778 mRNA. Translation: AAH60778.2. BC065278 mRNA. Translation: AAH65278.1. BC131534 mRNA. Translation: AAI31535.1. AF283512 mRNA. Translation: AAM73547.1. Different initiation.
IPI	IPI00168885. IPI00399364. IPI00749029.
RefSeq	NP_945314.1. NM_198963.1.
UniGene	Hs.468226.
3D structure databases
ProteinModelPortal	Q6P158.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q6P158. 1 interaction.
STRING	9606.ENSP00000295373.
PTM databases
PhosphoSite	Q6P158.
Polymorphism databases
DMDM	94710252.
Proteomic databases
PaxDb	Q6P158.
PeptideAtlas	Q6P158.
PRIDE	Q6P158.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000295373; ENSP00000295373; ENSG00000163214.
GeneID	90957.
KEGG	hsa:90957.
UCSC	uc002rre.3. human. uc002rrg.3. human.
Organism-specific databases
CTD	90957.
GeneCards	GC02M039025.
HGNC	HGNC:20086. DHX57.
HPA	HPA036160.
neXtProt	NX_Q6P158.
PharmGKB	PA134919698.
GenAtlas	Search...
Phylogenomic databases
eggNOG	COG1643.
HOVERGEN	HBG080658.
InParanoid	Q6P158.
KO	K13026.
OMA	RAYKGWQ.
OrthoDB	EOG4ZS929.
PhylomeDB	Q6P158.
Gene expression databases
ArrayExpress	Q6P158.
Bgee	Q6P158.
CleanEx	HS_DHX57.
Genevestigator	Q6P158.
GermOnline	ENSG00000163214. Homo sapiens.
Family and domain databases
InterPro	IPR011545. DNA/RNA_helicase_DEAD/DEAH_N. IPR002464. DNA/RNA_helicase_DEAH_CS. IPR011709. DUF1605. IPR007502. Helicase-assoc_dom. IPR014001. Helicase_ATP-bd. IPR001650. Helicase_C. IPR006575. RWD-domain. IPR009060. UBA-like. IPR015940. UBA/transl_elong_EF1B_N_euk. IPR000571. Znf_CCCH. [Graphical view]
Pfam	PF00270. DEAD. 1 hit. PF04408. HA2. 1 hit. PF00271. Helicase_C. 1 hit. PF07717. OB_NTP_bind. 1 hit. PF05773. RWD. 1 hit. PF00642. zf-CCCH. 1 hit. [Graphical view]
SMART	SM00487. DEXDc. 1 hit. SM00847. HA2. 1 hit. SM00490. HELICc. 1 hit. SM00356. ZnF_C3H1. 1 hit. [Graphical view]
SUPFAM	SSF46934. UBA_like. 1 hit.
PROSITE	PS00690. DEAH_ATP_HELICASE. 1 hit. PS51192. HELICASE_ATP_BIND_1. 1 hit. PS51194. HELICASE_CTER. 1 hit. PS50030. UBA. 1 hit. PS50103. ZF_C3H1. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	DHX57. human.
GenomeRNAi	90957.
NextBio	77048.

Entry information

Entry name

DHX57_HUMAN

Accession

Primary (citable) accession number: Q6P158
Secondary accession number(s): A2RRC7 , Q53SI4, Q6P9G1, Q7Z6H3, Q8NG17, Q96M33

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 2, 2006
Last sequence update:	May 2, 2006
Last modified:	May 1, 2013
This is version 93 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.