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Q6P158

- DHX57_HUMAN

UniProt

Q6P158 - DHX57_HUMAN

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Protein
Putative ATP-dependent RNA helicase DHX57
Gene
DHX57
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

Probable ATP-binding RNA helicase.

Catalytic activityi

ATP + H2O = ADP + phosphate.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri299 – 32628C3H1-type
Add
BLAST
Nucleotide bindingi567 – 5748ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. ATP-dependent helicase activity Source: InterPro
  3. metal ion binding Source: UniProtKB-KW
  4. poly(A) RNA binding Source: UniProtKB
Complete GO annotation...

Keywords - Molecular functioni

Helicase, Hydrolase

Keywords - Ligandi

ATP-binding, Metal-binding, Nucleotide-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Putative ATP-dependent RNA helicase DHX57 (EC:3.6.4.13)
Alternative name(s):
DEAH box protein 57
Gene namesi
Name:DHX57
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 2

Organism-specific databases

HGNCiHGNC:20086. DHX57.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134919698.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 13861386Putative ATP-dependent RNA helicase DHX57
PRO_0000233151Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei127 – 1271Phosphoserine3 Publications
Modified residuei475 – 4751Phosphoserine1 Publication
Modified residuei477 – 4771Phosphoserine1 Publication
Modified residuei480 – 4801Phosphoserine2 Publications

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ6P158.
PaxDbiQ6P158.
PeptideAtlasiQ6P158.
PRIDEiQ6P158.

PTM databases

PhosphoSiteiQ6P158.

Expressioni

Gene expression databases

ArrayExpressiQ6P158.
BgeeiQ6P158.
CleanExiHS_DHX57.
GenevestigatoriQ6P158.

Organism-specific databases

HPAiHPA036160.

Interactioni

Protein-protein interaction databases

BioGridi124783. 10 interactions.
IntActiQ6P158. 2 interactions.
MINTiMINT-4774949.
STRINGi9606.ENSP00000295373.

Structurei

3D structure databases

ProteinModelPortaliQ6P158.
SMRiQ6P158. Positions 464-804, 1031-1309.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini180 – 22041UBA
Add
BLAST
Domaini554 – 721168Helicase ATP-binding
Add
BLAST
Domaini830 – 1010181Helicase C-terminal
Add
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili101 – 12525 Reviewed prediction
Add
BLAST

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi668 – 6714DEVH box

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi9 – 4941Gly-rich
Add
BLAST

Sequence similaritiesi

Contains 1 UBA domain.

Keywords - Domaini

Coiled coil, Zinc-finger

Phylogenomic databases

eggNOGiCOG1643.
HOVERGENiHBG080658.
InParanoidiQ6P158.
KOiK13026.
OMAiTQCFSET.
OrthoDBiEOG7SV0TS.
PhylomeDBiQ6P158.
TreeFamiTF324744.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
4.10.1000.10. 1 hit.
InterProiIPR011545. DNA/RNA_helicase_DEAD/DEAH_N.
IPR002464. DNA/RNA_helicase_DEAH_CS.
IPR011709. DUF1605.
IPR007502. Helicase-assoc_dom.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR006575. RWD-domain.
IPR009060. UBA-like.
IPR015940. UBA/transl_elong_EF1B_N_euk.
IPR000571. Znf_CCCH.
[Graphical view]
PfamiPF00270. DEAD. 1 hit.
PF04408. HA2. 1 hit.
PF00271. Helicase_C. 1 hit.
PF07717. OB_NTP_bind. 1 hit.
PF05773. RWD. 1 hit.
PF00642. zf-CCCH. 1 hit.
[Graphical view]
SMARTiSM00487. DEXDc. 1 hit.
SM00847. HA2. 1 hit.
SM00490. HELICc. 1 hit.
SM00356. ZnF_C3H1. 1 hit.
[Graphical view]
SUPFAMiSSF46934. SSF46934. 1 hit.
SSF52540. SSF52540. 2 hits.
PROSITEiPS00690. DEAH_ATP_HELICASE. 1 hit.
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
PS50030. UBA. 1 hit.
PS50103. ZF_C3H1. 1 hit.
[Graphical view]

Sequences (3)i

Sequence statusi: Complete.

This entry describes 3 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q6P158-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

MSSSVRRKGK PGKGGGKGSS RGGRGGRSHA SKSHGSGGGG GGGGGGGGGN     50
RKASSRIWDD GDDFCIFSES RRPSRPSNSN ISKGESRPKW KPKAKVPLQT 100
LHMTSENQEK VKALLRDLQE QDADAGSERG LSGEEEDDEP DCCNDERYWP 150
AGQEPSLVPD LDPLEYAGLA SVEPYVPEFT VSPFAVQKLS RYGFNTERCQ 200
AVLRMCDGDV GASLEHLLTQ CFSETFGERM KISEAVNQIS LDECMEQRQE 250
EAFALKSICG EKFIERIQNR VWTIGLELEY LTSRFRKSKP KESTKNVQEN 300
SLEICKFYLK GNCKFGSKCR FKHEVPPNQI VGRIERSVDD SHLNAIEDAS 350
FLYELEIRFS KDHKYPYQAP LVAFYSTNEN LPLACRLHIS EFLYDKALTF 400
AETSEPVVYS LITLLEEESE IVKLLTNTHH KYSDPPVNFL PVPSRTRINN 450
PACHKTVIPN NSFVSNQIPE VEKASESEES DEDDGPAPVI VENESYVNLK 500
KKISKRYDWQ AKSVHAENGK ICKQFRMKQA SRQFQSILQE RQSLPAWEER 550
ETILNLLRKH QVVVISGMTG CGKTTQIPQF ILDDSLNGPP EKVANIICTQ 600
PRRISAISVA ERVAKERAER VGLTVGYQIR LESVKSSATR LLYCTTGVLL 650
RRLEGDTALQ GVSHIIVDEV HERTEESDFL LLVLKDIVSQ RPGLQVILMS 700
ATLNAELFSD YFNSCPVITI PGRTFPVDQF FLEDAIAVTR YVLQDGSPYM 750
RSMKQISKEK LKARRNRTAF EEVEEDLRLS LHLQDQDSVK DAVPDQQLDF 800
KQLLARYKGV SKSVIKTMSI MDFEKVNLEL IEALLEWIVD GKHSYPPGAI 850
LVFLPGLAEI KMLYEQLQSN SLFNNRRSNR CVIHPLHSSL SSEEQQAVFV 900
KPPAGVTKII ISTNIAETSI TIDDVVYVID SGKMKEKRYD ASKGMESLED 950
TFVSQANALQ RKGRAGRVAS GVCFHLFTSH HYNHQLLKQQ LPEIQRVPLE 1000
QLCLRIKILE MFSAHNLQSV FSRLIEPPHT DSLRASKIRL RDLGALTPDE 1050
RLTPLGYHLA SLPVDVRIGK LMLFGSIFRC LDPALTIAAS LAFKSPFVSP 1100
WDKKEEANQK KLEFAFANSD YLALLQAYKG WQLSTKEGVR ASYNYCRQNF 1150
LSGRVLQEMA SLKRQFTELL SDIGFAREGL RAREIEKRAQ GGDGVLDATG 1200
EEANSNAENP KLISAMLCAA LYPNVVQVKS PEGKFQKTST GAVRMQPKSA 1250
ELKFVTKNDG YVHIHPSSVN YQVRHFDSPY LLYHEKIKTS RVFIRDCSMV 1300
SVYPLVLFGG GQVNVQLQRG EFVVSLDDGW IRFVAASHQV AELVKELRCE 1350
LDQLLQDKIK NPSIDLCTCP RGSRIISTIV KLVTTQ 1386
Length:1,386
Mass (Da):155,604
Last modified:May 2, 2006 - v2
Checksum:iFFF62BD4BF4C1F4D
GO
Isoform 2 (identifier: Q6P158-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     636-658: SSATRLLYCTTGVLLRRLEGDTA → VCMLCLFPGNRNLWFLGIKSFGG
     659-1386: Missing.

Note: No experimental confirmation available.

Show »
Length:658
Mass (Da):73,602
Checksum:i570E49695D5B05A3
GO
Isoform 3 (identifier: Q6P158-3) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-102: Missing.
     530-535: ASRQFQ → VLNSHM
     536-1386: Missing.

Note: No experimental confirmation available.

Show »
Length:433
Mass (Da):49,508
Checksum:i1B83D88C94570046
GO

Sequence cautioni

The sequence AAM73547.1 differs from that shown. Reason: Erroneous initiation.
The sequence AAY24256.1 differs from that shown. Reason: Erroneous gene model prediction.

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti410 – 4101S → F.
Corresponds to variant rs11893062 [ dbSNP | Ensembl ].
VAR_052190
Natural varianti433 – 4331S → G.
Corresponds to variant rs35371077 [ dbSNP | Ensembl ].
VAR_033861
Natural varianti587 – 5871N → S.2 Publications
Corresponds to variant rs7598922 [ dbSNP | Ensembl ].
VAR_052191

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 102102Missing in isoform 3.
VSP_018056Add
BLAST
Alternative sequencei530 – 5356ASRQFQ → VLNSHM in isoform 3.
VSP_018057
Alternative sequencei536 – 1386851Missing in isoform 3.
VSP_018058Add
BLAST
Alternative sequencei636 – 65823SSATR…EGDTA → VCMLCLFPGNRNLWFLGIKS FGG in isoform 2.
VSP_018059Add
BLAST
Alternative sequencei659 – 1386728Missing in isoform 2.
VSP_018060Add
BLAST

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti474 – 4741A → T in BAB71479. 1 Publication
Sequence conflicti976 – 9761L → V in AAM73547. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK057423 mRNA. Translation: BAB71479.1.
AC018693 Genomic DNA. Translation: AAY24256.1. Sequence problems.
BC053623 mRNA. Translation: AAH53623.1.
BC060778 mRNA. Translation: AAH60778.2.
BC065278 mRNA. Translation: AAH65278.1.
BC131534 mRNA. Translation: AAI31535.1.
AF283512 mRNA. Translation: AAM73547.1. Different initiation.
CCDSiCCDS1800.1. [Q6P158-1]
RefSeqiNP_945314.1. NM_198963.1. [Q6P158-1]
UniGeneiHs.468226.

Genome annotation databases

EnsembliENST00000295373; ENSP00000295373; ENSG00000163214. [Q6P158-1]
GeneIDi90957.
KEGGihsa:90957.
UCSCiuc002rre.3. human. [Q6P158-1]
uc002rrg.3. human. [Q6P158-2]

Polymorphism databases

DMDMi94710252.

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK057423 mRNA. Translation: BAB71479.1 .
AC018693 Genomic DNA. Translation: AAY24256.1 . Sequence problems.
BC053623 mRNA. Translation: AAH53623.1 .
BC060778 mRNA. Translation: AAH60778.2 .
BC065278 mRNA. Translation: AAH65278.1 .
BC131534 mRNA. Translation: AAI31535.1 .
AF283512 mRNA. Translation: AAM73547.1 . Different initiation.
CCDSi CCDS1800.1. [Q6P158-1 ]
RefSeqi NP_945314.1. NM_198963.1. [Q6P158-1 ]
UniGenei Hs.468226.

3D structure databases

ProteinModelPortali Q6P158.
SMRi Q6P158. Positions 464-804, 1031-1309.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 124783. 10 interactions.
IntActi Q6P158. 2 interactions.
MINTi MINT-4774949.
STRINGi 9606.ENSP00000295373.

PTM databases

PhosphoSitei Q6P158.

Polymorphism databases

DMDMi 94710252.

Proteomic databases

MaxQBi Q6P158.
PaxDbi Q6P158.
PeptideAtlasi Q6P158.
PRIDEi Q6P158.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000295373 ; ENSP00000295373 ; ENSG00000163214 . [Q6P158-1 ]
GeneIDi 90957.
KEGGi hsa:90957.
UCSCi uc002rre.3. human. [Q6P158-1 ]
uc002rrg.3. human. [Q6P158-2 ]

Organism-specific databases

CTDi 90957.
GeneCardsi GC02M039025.
HGNCi HGNC:20086. DHX57.
HPAi HPA036160.
neXtProti NX_Q6P158.
PharmGKBi PA134919698.
GenAtlasi Search...

Phylogenomic databases

eggNOGi COG1643.
HOVERGENi HBG080658.
InParanoidi Q6P158.
KOi K13026.
OMAi TQCFSET.
OrthoDBi EOG7SV0TS.
PhylomeDBi Q6P158.
TreeFami TF324744.

Miscellaneous databases

ChiTaRSi DHX57. human.
GeneWikii DHX57.
GenomeRNAii 90957.
NextBioi 77048.
PROi Q6P158.

Gene expression databases

ArrayExpressi Q6P158.
Bgeei Q6P158.
CleanExi HS_DHX57.
Genevestigatori Q6P158.

Family and domain databases

Gene3Di 3.40.50.300. 2 hits.
4.10.1000.10. 1 hit.
InterProi IPR011545. DNA/RNA_helicase_DEAD/DEAH_N.
IPR002464. DNA/RNA_helicase_DEAH_CS.
IPR011709. DUF1605.
IPR007502. Helicase-assoc_dom.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR006575. RWD-domain.
IPR009060. UBA-like.
IPR015940. UBA/transl_elong_EF1B_N_euk.
IPR000571. Znf_CCCH.
[Graphical view ]
Pfami PF00270. DEAD. 1 hit.
PF04408. HA2. 1 hit.
PF00271. Helicase_C. 1 hit.
PF07717. OB_NTP_bind. 1 hit.
PF05773. RWD. 1 hit.
PF00642. zf-CCCH. 1 hit.
[Graphical view ]
SMARTi SM00487. DEXDc. 1 hit.
SM00847. HA2. 1 hit.
SM00490. HELICc. 1 hit.
SM00356. ZnF_C3H1. 1 hit.
[Graphical view ]
SUPFAMi SSF46934. SSF46934. 1 hit.
SSF52540. SSF52540. 2 hits.
PROSITEi PS00690. DEAH_ATP_HELICASE. 1 hit.
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
PS50030. UBA. 1 hit.
PS50103. ZF_C3H1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3).
    Tissue: Testis.
  2. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
    Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
    , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
    Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2), VARIANT SER-587.
    Tissue: Skin.
  4. "Molecular cloning of a new member of DEAH-box RNA/DNA helicase gene family."
    Lin S., Ying K., Wang Z., Xie Y., Mao Y.
    Submitted (JUN-2000) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 405-1386 (ISOFORM 1), VARIANT SER-587.
    Tissue: Brain.
  5. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
    Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M.
    Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-127 AND SER-480, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  6. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-475; SER-477 AND SER-480, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  7. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
    Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S.
    Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  8. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
    Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
    Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-127, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  9. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  10. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
    Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
    Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-127, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiDHX57_HUMAN
AccessioniPrimary (citable) accession number: Q6P158
Secondary accession number(s): A2RRC7
, Q53SI4, Q6P9G1, Q7Z6H3, Q8NG17, Q96M33
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 2, 2006
Last sequence update: May 2, 2006
Last modified: September 3, 2014
This is version 106 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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