Reviewed, UniProtKB/Swiss-Prot Q6P0U0 (NAGA_DANRE)

Names and origin

Protein names

Recommended name:
    Putative N-acetylglucosamine-6-phosphate deacetylase
    EC=3.5.1.25
Alternative name(s):
    GlcNAc 6-P deacetylase
    Amidohydrolase domain-containing protein 2

Gene names

Name:	amdhd2
ORF Names:	zgc:77775

Organism

Danio rerio (Zebrafish) (Brachydanio rerio)

Taxonomic identifier

7955 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Cyprinidae › Danio

Protein attributes

Sequence length	404 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Catalytic activity	N-acetyl-D-glucosamine 6-phosphate + H2O = D-glucosamine 6-phosphate + acetate.
Sequence similarities	Belongs to the nagA family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism
Molecular function	Hydrolase
Gene Ontology (GO)
Biological process	N-acetylglucosamine metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	N-acetylglucosamine-6-phosphate deacetylase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 404	404	Putative N-acetylglucosamine-6-phosphate deacetylase		PRO_0000315779

Sequences

	Sequence		Length	Mass (Da)
	Q6P0U0-1 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: BCF27EA3F4D1226F	FASTA	404	43,686
	10 20 30 40 50 60 MPSNKSVSDA PITQFVNCRI LKNHKLQWED LWVREGKILN PEKLFFDEQG FADHRVDCEN 70 80 90 100 110 120 KIIAPGFIDV QLNGGYGIDF SQASSDIRGG VALVAKKILE HGVTSFCPTL VTSPPHIYHK 130 140 150 160 170 180 VIPELRVQDG GPEGAGVLGI HLEGPFISEE KRGAHPPKFL RTFQSGGVAD LMETYGQLEN 190 200 210 220 230 240 VAMVTLAPEL TNSAAAIHEL SSRGITVSVG HSMADLSQAE EAVQNGATFI THLFNAMLPF 250 260 270 280 290 300 HHRDPGIVGL LTSDRIPPGR TVYYGMIADG IHTHPAALRI AHRAHPAGLV LVTDAVTAMG 310 320 330 340 350 360 LPPGRHTLGQ QQIDIQGLHA YVAGTTTLSG SIATMDMCVR HFREASGCTV EAALEAASLH 370 380 390 400 PAQLLGISHR KGTLEFGADA DFIVLDDMLT VRETYIAGQQ VWRK

References

[1]	NIH - Zebrafish Gene Collection (ZGC) project Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	BC065449 mRNA. Translation: AAH65449.1.
IPI	IPI00499477.
RefSeq	NP_991244.1.
UniGene	Dr.84266
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q6P0U0.
Proteomic databases
PRIDE	Q6P0U0.
Genome annotation databases
Ensembl	ENSDART00000022967; ENSDARP00000011842; ENSDARG00000021293; Danio rerio. [Genome view]
GeneID	402981.
KEGG	dre:402981.
Organism-specific databases
ZFIN	ZDB-GENE-040426-1871. zgc:77775.
Phylogenomic databases
HOGENOM	Q6P0U0.
HOVERGEN	Q6P0U0.
OMA	QGLHAYV.
Enzyme and pathway databases
BRENDA	3.5.1.25. 96826.
Gene expression databases
ArrayExpress	Q6P0U0.
Bgee	Q6P0U0.
Family and domain databases
InterPro	IPR006680. Amidohydro_1. IPR003764. GlcNAc_6-P_deAcase. [Graphical view]
Pfam	PF01979. Amidohydro_1. 2 hits. [Graphical view]
TIGRFAMs	TIGR00221. nagA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

NAGA_DANRE

Accession

Primary (citable) accession number: Q6P0U0

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	July 5, 2004
Last modified:	November 3, 2009
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

Zebrafish annotation project