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Protein
Submitted name:

DST protein

Gene

DST

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
DST proteinImported
Submitted name:
DystoninImported
Gene namesi
Name:DSTImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 6

Organism-specific databases

EuPathDBiHostDB:ENSG00000151914.18.
HGNCiHGNC:1090. DST.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000151914.

PTM / Processingi

Proteomic databases

MaxQBiQ6P0N6.

Expressioni

Gene expression databases

BgeeiENSG00000151914.
ExpressionAtlasiQ6P0N6. baseline and differential.

Interactioni

GO - Molecular functioni

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili408 – 442Sequence analysisAdd BLAST35
Coiled coili514 – 537Sequence analysisAdd BLAST24
Coiled coili882 – 916Sequence analysisAdd BLAST35

Keywords - Domaini

Coiled coilSequence analysis, RepeatSAAS annotation

Phylogenomic databases

eggNOGiENOG410IQBP. Eukaryota.
ENOG410XP41. LUCA.
GeneTreeiENSGT00760000119163.
HOGENOMiHOG000203353.
HOVERGENiHBG062337.
KOiK10382.

Family and domain databases

InterProiView protein in InterPro
IPR029926. Dystonin.
IPR018159. Spectrin/alpha-actinin.
IPR002017. Spectrin_repeat.
PANTHERiPTHR11915:SF335. PTHR11915:SF335. 1 hit.
PfamiView protein in Pfam
PF00435. Spectrin. 1 hit.
SMARTiView protein in SMART
SM00150. SPEC. 3 hits.

Sequencei

Sequence statusi: Complete.

Q6P0N6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHSSSYSYRS SDSVFSNTTS TRTSLDSNEN LLLVHCGPTL INSCISFGSE
60 70 80 90 100
SFDGHRLEML QQIANRVQRD SVICEDKLIL AGNALQSDSK RLESGVQFQN
110 120 130 140 150
EAEIAGYILE CENLLRQHVI DVQILIDGKY YQADQLVQRV AKLRDEIMAL
160 170 180 190 200
RNECSSVYSK GRILTTEQTK LMISGITQSL NSGFAQTLHP SLTSGLTQSL
210 220 230 240 250
TPSLTSSSMT SGLSSGMTSR LTPSVTPAYT PGFPSGLVPN FSSGVEPNSL
260 270 280 290 300
QTLKLMQIRK PLLKSSLLDQ NLTEEEINMK FVQDLLNWVD EMQVQLDRTE
310 320 330 340 350
WGSDLPSVES HLENHKNVHR AIEEFESSLK EAKISEIQMT APLKLTYAEK
360 370 380 390 400
LHRLESQYAK LLNTSRNQER HLDTLHNFVS RATNELIWLN EKEEEEVAYD
410 420 430 440 450
WSERNTNIAR KKDYHAELMR ELDQKEENIK SVQEIAEQLL LENHPARLTI
460 470 480 490 500
EAYRAAMQTQ WSWILQLCQC VEQHIKENTA YFEFFNDAKE ATDYLRNLKD
510 520 530 540 550
AIQRKYSCDR SSSIHKLEDL VQESMEEKEE LLQYKSTIAN LMGKAKTIIQ
560 570 580 590 600
LKPRNSDCPL KTSIPIKAIC DYRQIEITIY KDDECVLANN SHRAKWKVIS
610 620 630 640 650
PTGNEAMVPS VCFTVPPPNK EAVDLANRIE QQYQNVLTLW HESHINMKSV
660 670 680 690 700
VSWHYLINEI DRIRASNVAS IKTMLPGEHQ QVLSNLQSRF EDFLEDSQES
710 720 730 740 750
QVFSGSDITQ LEKEVNVCKQ YYQELLKSAE REEQEESVYN LYISEVRNIR
760 770 780 790 800
LRLENCEDRL IRQIRTPLER DDLHESVFRI TEQEKLKKEL ERLKDDLGTI
810 820 830 840 850
TNKCEEFFSQ AAASSSVPTL RSELNVVLQN MNQVYSMSST YIDKLKTVNL
860 870 880 890 900
VLKNTQAAEA LVKLYETKLC EEEAVIADKN NIENLISTLK QWRSEVDEKR
910 920 930 940 950
QVFHALEDEL QKAKAISDEM FKTYKERDLD FDWHKEKADQ LVERWQNVHV
960 970 980 990 1000
QIDNRLRDLE GIGKSLKYYR DTYHPLDDWI QQVETTQRKI QENQPENSKT
1010 1020 1030 1040 1050
LATQLNQQKM LVSEIEMKQS KMDECQKYAE QYSATVKDYE LQTMTYRAMV
1060 1070 1080 1090 1100
DSQQKSPVKR RRMQSSADLI IQEFMDLRTR YTALVTLMTQ YIKFAGDSLK
1110 1120 1130 1140
RLEEEEVIIN SEHPVNIKEL EMSSNYSVVW ESKTCFMINL CGR
Length:1,143
Mass (Da):132,290
Last modified:July 5, 2004 - v1
Checksum:iF4A7E9590A05067A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL096710 Genomic DNA. No translation available.
AL137008 Genomic DNA. No translation available.
AL512422 Genomic DNA. No translation available.
AL512448 Genomic DNA. No translation available.
AL590005 Genomic DNA. No translation available.
AL590037 Genomic DNA. No translation available.
KF458172 Genomic DNA. No translation available.
BC065536 mRNA. Translation: AAH65536.1.
RefSeqiNP_001138241.1. NM_001144769.2.
NP_001138242.1. NM_001144770.1.
NP_899236.1. NM_183380.3.
UniGeneiHs.604915.
Hs.669931.
Hs.728928.
Hs.735651.

Genome annotation databases

EnsembliENST00000518935; ENSP00000431003; ENSG00000151914.
GeneIDi667.
KEGGihsa:667.
UCSCiuc003pdd.6. human.

Similar proteinsi

Entry informationi

Entry nameiQ6P0N6_HUMAN
AccessioniPrimary (citable) accession number: Q6P0N6
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: September 27, 2017
This is version 109 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported