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Q6P0N0

- M18BP_HUMAN

UniProt

Q6P0N0 - M18BP_HUMAN

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Protein

Mis18-binding protein 1

Gene

MIS18BP1

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli

Functioni

Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.2 Publications

GO - Molecular functioni

  1. chromatin binding Source: InterPro
  2. DNA binding Source: UniProtKB-KW

GO - Biological processi

  1. CENP-A containing nucleosome assembly Source: Reactome
  2. mitotic nuclear division Source: UniProtKB-KW
  3. nucleosome assembly Source: Reactome
Complete GO annotation...

Keywords - Biological processi

Cell cycle, Cell division, Mitosis

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

ReactomeiREACT_22186. Deposition of new CENPA-containing nucleosomes at the centromere.

Names & Taxonomyi

Protein namesi
Recommended name:
Mis18-binding protein 1
Alternative name(s):
Kinetochore-associated protein KNL-2 homolog
Short name:
HsKNL-2
P243
Gene namesi
Name:MIS18BP1
Synonyms:C14orf106, KIAA1903, KNL2, M18BP1
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 14

Organism-specific databases

HGNCiHGNC:20190. MIS18BP1.

Subcellular locationi

Nucleus. Chromosome. Chromosomecentromere
Note: Associated with centromeres in interphase cells, from late anaphase to the G1 phase. Not detected on centromeres during earlier phases of mitosis. Associated with chromatin.

GO - Cellular componenti

  1. chromosome, centromeric region Source: UniProtKB-KW
  2. nucleoplasm Source: Reactome
Complete GO annotation...

Keywords - Cellular componenti

Centromere, Chromosome, Nucleus

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134927557.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 11321132Mis18-binding protein 1PRO_0000197140Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei110 – 1101Phosphoserine1 Publication
Modified residuei135 – 1351Phosphoserine1 Publication
Modified residuei172 – 1721Phosphoserine1 Publication
Modified residuei299 – 2991Phosphoserine1 Publication
Modified residuei653 – 6531Phosphothreonine3 Publications
Modified residuei772 – 7721Phosphoserine1 Publication
Modified residuei773 – 7731Phosphoserine1 Publication
Modified residuei821 – 8211Phosphothreonine1 Publication
Modified residuei824 – 8241Phosphoserine1 Publication
Modified residuei860 – 8601Phosphoserine1 Publication
Modified residuei1008 – 10081Phosphoserine4 Publications
Modified residuei1086 – 10861Phosphoserine1 Publication
Modified residuei1087 – 10871Phosphothreonine1 Publication
Modified residuei1089 – 10891Phosphothreonine1 Publication
Modified residuei1104 – 11041Phosphoserine4 Publications
Modified residuei1116 – 11161Phosphoserine2 Publications

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ6P0N0.
PaxDbiQ6P0N0.
PRIDEiQ6P0N0.

PTM databases

PhosphoSiteiQ6P0N0.

Expressioni

Gene expression databases

BgeeiQ6P0N0.
CleanExiHS_C14orf106.
ExpressionAtlasiQ6P0N0. baseline and differential.
GenevestigatoriQ6P0N0.

Organism-specific databases

HPAiHPA006504.

Interactioni

Subunit structurei

Interacts (via N-terminus) with FLNA (via N-terminus) By similarity. Interacts with SP1 Probable. Interacts with MIS18A. Identified in a complex containing MIS18A, MIS18B, MIS18BP1, RBBP7 and RBBP4.By similarity2 PublicationsCurated

Protein-protein interaction databases

BioGridi120601. 6 interactions.
MINTiMINT-4992022.
STRINGi9606.ENSP00000309790.

Structurei

Secondary structure

1
1132
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi882 – 89413
Beta strandi897 – 9015
Helixi902 – 9098
Turni910 – 9123
Helixi915 – 92410
Beta strandi925 – 9295
Beta strandi934 – 9363

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1WGXNMR-A877-936[»]
ProteinModelPortaliQ6P0N0.
SMRiQ6P0N0. Positions 877-936.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ6P0N0.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini875 – 93056SANTPROSITE-ProRule annotationAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi1010 – 10134Poly-Asp

Sequence similaritiesi

Contains 1 SANT domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiNOG73415.
GeneTreeiENSGT00390000007395.
HOGENOMiHOG000113431.
InParanoidiQ6P0N0.
OMAiNDCDKYV.
OrthoDBiEOG77M8R3.
PhylomeDBiQ6P0N0.
TreeFamiTF106401.

Family and domain databases

InterProiIPR009057. Homeodomain-like.
IPR001005. SANT/Myb.
IPR017884. SANT_dom.
IPR015216. SANTA.
[Graphical view]
PfamiPF09133. SANTA. 1 hit.
[Graphical view]
SMARTiSM00717. SANT. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS51293. SANT. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q6P0N0-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MIATPLKHSR IYLPPEASSQ RRNLPMDAIF FDSIPSGTLT PVKDLVKYQN
60 70 80 90 100
SSLKLNDHKK NQFLKMTTFN NKNIFQSTML TEATTSNSSL DISAIKPNKD
110 120 130 140 150
GLKNKANYES PGKIFLRMKE KVLRDKQEQP SRNSSLLEPQ KSGNNETFTP
160 170 180 190 200
NRVEKKKLQH TYLCEEKENN KSFQSDDSSL RASVQGVPLE SSNNDIFLPV
210 220 230 240 250
KQKIQCQQEK KAPLHNLTYE LPTLNQEQEN FLAVEARNKT LTRAQLAKQI
260 270 280 290 300
FHSKESIVAT TKSKKDTFVL ESVDSADEQF QNTNAETLST NCIPIKNGSL
310 320 330 340 350
LMVSDSERTT EGTSQQKVKE GNGKTVPGET GLPGSMKDTC KIVLATPRLH
360 370 380 390 400
ITIPRRSKRN ISKLSPPRIF QTVTNGLKKN QVVQLQEWMI KSINNNTAIC
410 420 430 440 450
VEGKLIDVTN IYWHSNVIIE RIEHNKLRTI SGNVYILKGM IDQISMKEAG
460 470 480 490 500
YPNYLIRKFM FGFPENWKEH IDNFLEQLRA GEKNREKTKQ KQKTGRSVRD
510 520 530 540 550
IRKSMKNDAR ENQTDTAQRA TTTYDFDCDN LELKSNKHSE SPGATELNMC
560 570 580 590 600
HSNCQNKPTL RFPDDQVNNT IQNGGGDDLS NQELIGKKEY KMSSKKLKIG
610 620 630 640 650
ERTNERIIKS QKQETTEELD VSIDILTSRE QFFSDEERKY MAINQKKAYI
660 670 680 690 700
LVTPLKSRKV IEQRCMRYNL SAGTIKAVTD FVIPECQKKS PISKSMGTLE
710 720 730 740 750
NTFEGHKSKN KEDCDERDLL TVNRKIKISN LEKEQMLTSD FKKNTRLLPK
760 770 780 790 800
LKKIENQVAM SFYKHQSSPD LSSEESETEK EIKRKAEVKK TKAGNTKEAV
810 820 830 840 850
VHLRKSTRNT SNIPVILEPE TEESENEFYI KQKKARPSVK ETLQKSGVRK
860 870 880 890 900
EFPITEAVGS DKTNRHPLEC LPGLIQDKEW NEKELQKLHC AFASLPKHKP
910 920 930 940 950
GFWSEVAAAV GSRSPEECQR KYMENPRGKG SQKHVTKKKP ANSKGQNGKR
960 970 980 990 1000
GDADQKQTIK ITAKVGTLKR KQQMREFLEQ LPKDDHDDFF STTPLQHQRI
1010 1020 1030 1040 1050
LLPSFQDSED DDDILPNMDK NPTTPSSVIF PLVKTPQCQH VSPGMLGSIN
1060 1070 1080 1090 1100
RNDCDKYVFR MQKYHKSNGG IVWGNIKKKL VETDFSTPTP RRKTPFNTDL
1110 1120 1130
GENSGIGKLF TNAVESLDEE EKDYYFSNSD SA
Length:1,132
Mass (Da):129,085
Last modified:July 5, 2004 - v1
Checksum:i92F2787CD4687059
GO
Isoform 2 (identifier: Q6P0N0-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     391-1132: Missing.

Note: No experimental confirmation available.

Show »
Length:390
Mass (Da):43,994
Checksum:iB4B1B945CE91C8A8
GO

Sequence cautioni

The sequence AK002048 differs from that shown. Reason: Frameshift at position 157.
The sequence BAB67796.1 differs from that shown. Reason: Frameshift at position 154.

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti510 – 5101R → Q in BAB67796. (PubMed:11572484)Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti164 – 1641C → R.
Corresponds to variant rs1269008 [ dbSNP | Ensembl ].
VAR_050184
Natural varianti347 – 3471P → R.
Corresponds to variant rs34168608 [ dbSNP | Ensembl ].
VAR_050185
Natural varianti583 – 5831E → D.
Corresponds to variant rs34101857 [ dbSNP | Ensembl ].
VAR_050186
Natural varianti851 – 8511E → Q.
Corresponds to variant rs34402741 [ dbSNP | Ensembl ].
VAR_050187

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei391 – 1132742Missing in isoform 2. 1 PublicationVSP_014105Add
BLAST

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB067490 mRNA. Translation: BAB67796.1. Frameshift.
AK002048 mRNA. No translation available.
AL121809 Genomic DNA. No translation available.
CH471078 Genomic DNA. Translation: EAW65778.1.
CH471078 Genomic DNA. Translation: EAW65779.1.
CH471078 Genomic DNA. Translation: EAW65780.1.
BC051885 mRNA. Translation: AAH51885.1.
BC065544 mRNA. Translation: AAH65544.1.
AJ242977 mRNA. Translation: CAB45134.1.
CCDSiCCDS9684.1. [Q6P0N0-1]
RefSeqiNP_060823.3. NM_018353.4. [Q6P0N0-1]
XP_005267890.1. XM_005267833.2. [Q6P0N0-1]
UniGeneiHs.732769.

Genome annotation databases

EnsembliENST00000310806; ENSP00000309790; ENSG00000129534. [Q6P0N0-1]
GeneIDi55320.
KEGGihsa:55320.
UCSCiuc001wwf.3. human. [Q6P0N0-1]

Polymorphism databases

DMDMi68052324.

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB067490 mRNA. Translation: BAB67796.1 . Frameshift.
AK002048 mRNA. No translation available.
AL121809 Genomic DNA. No translation available.
CH471078 Genomic DNA. Translation: EAW65778.1 .
CH471078 Genomic DNA. Translation: EAW65779.1 .
CH471078 Genomic DNA. Translation: EAW65780.1 .
BC051885 mRNA. Translation: AAH51885.1 .
BC065544 mRNA. Translation: AAH65544.1 .
AJ242977 mRNA. Translation: CAB45134.1 .
CCDSi CCDS9684.1. [Q6P0N0-1 ]
RefSeqi NP_060823.3. NM_018353.4. [Q6P0N0-1 ]
XP_005267890.1. XM_005267833.2. [Q6P0N0-1 ]
UniGenei Hs.732769.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
1WGX NMR - A 877-936 [» ]
ProteinModelPortali Q6P0N0.
SMRi Q6P0N0. Positions 877-936.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 120601. 6 interactions.
MINTi MINT-4992022.
STRINGi 9606.ENSP00000309790.

PTM databases

PhosphoSitei Q6P0N0.

Polymorphism databases

DMDMi 68052324.

Proteomic databases

MaxQBi Q6P0N0.
PaxDbi Q6P0N0.
PRIDEi Q6P0N0.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000310806 ; ENSP00000309790 ; ENSG00000129534 . [Q6P0N0-1 ]
GeneIDi 55320.
KEGGi hsa:55320.
UCSCi uc001wwf.3. human. [Q6P0N0-1 ]

Organism-specific databases

CTDi 55320.
GeneCardsi GC14M045673.
HGNCi HGNC:20190. MIS18BP1.
HPAi HPA006504.
neXtProti NX_Q6P0N0.
PharmGKBi PA134927557.
HUGEi Search...
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG73415.
GeneTreei ENSGT00390000007395.
HOGENOMi HOG000113431.
InParanoidi Q6P0N0.
OMAi NDCDKYV.
OrthoDBi EOG77M8R3.
PhylomeDBi Q6P0N0.
TreeFami TF106401.

Enzyme and pathway databases

Reactomei REACT_22186. Deposition of new CENPA-containing nucleosomes at the centromere.

Miscellaneous databases

EvolutionaryTracei Q6P0N0.
GeneWikii C14orf106.
GenomeRNAii 55320.
NextBioi 59574.
PROi Q6P0N0.

Gene expression databases

Bgeei Q6P0N0.
CleanExi HS_C14orf106.
ExpressionAtlasi Q6P0N0. baseline and differential.
Genevestigatori Q6P0N0.

Family and domain databases

InterProi IPR009057. Homeodomain-like.
IPR001005. SANT/Myb.
IPR017884. SANT_dom.
IPR015216. SANTA.
[Graphical view ]
Pfami PF09133. SANTA. 1 hit.
[Graphical view ]
SMARTi SM00717. SANT. 1 hit.
[Graphical view ]
SUPFAMi SSF46689. SSF46689. 1 hit.
PROSITEi PS51293. SANT. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins."
    Nagase T., Kikuno R., Ohara O.
    DNA Res. 8:179-187(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Tissue: Brain.
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
    Tissue: Placenta.
  3. "The DNA sequence and analysis of human chromosome 14."
    Heilig R., Eckenberg R., Petit J.-L., Fonknechten N., Da Silva C., Cattolico L., Levy M., Barbe V., De Berardinis V., Ureta-Vidal A., Pelletier E., Vico V., Anthouard V., Rowen L., Madan A., Qin S., Sun H., Du H.
    , Pepin K., Artiguenave F., Robert C., Cruaud C., Bruels T., Jaillon O., Friedlander L., Samson G., Brottier P., Cure S., Segurens B., Aniere F., Samain S., Crespeau H., Abbasi N., Aiach N., Boscus D., Dickhoff R., Dors M., Dubois I., Friedman C., Gouyvenoux M., James R., Madan A., Mairey-Estrada B., Mangenot S., Martins N., Menard M., Oztas S., Ratcliffe A., Shaffer T., Trask B., Vacherie B., Bellemere C., Belser C., Besnard-Gonnet M., Bartol-Mavel D., Boutard M., Briez-Silla S., Combette S., Dufosse-Laurent V., Ferron C., Lechaplais C., Louesse C., Muselet D., Magdelenat G., Pateau E., Petit E., Sirvain-Trukniewicz P., Trybou A., Vega-Czarny N., Bataille E., Bluet E., Bordelais I., Dubois M., Dumont C., Guerin T., Haffray S., Hammadi R., Muanga J., Pellouin V., Robert D., Wunderle E., Gauguet G., Roy A., Sainte-Marthe L., Verdier J., Verdier-Discala C., Hillier L.W., Fulton L., McPherson J., Matsuda F., Wilson R., Scarpelli C., Gyapay G., Wincker P., Saurin W., Quetier F., Waterston R., Hood L., Weissenbach J.
    Nature 421:601-607(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Tissue: Testis and Uterus.
  6. "A set of proteins interacting with transcription factor Sp1 identified in a two-hybrid screening."
    Gunther M., Laithier M., Brison O.
    Mol. Cell. Biochem. 210:131-142(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 523-760, INTERACTION WITH SP1.
    Tissue: Colon carcinoma.
  7. "Priming of centromere for CENP-A recruitment by human hMis18alpha, hMis18beta, and M18BP1."
    Fujita Y., Hayashi T., Kiyomitsu T., Toyoda Y., Kokubu A., Obuse C., Yanagida M.
    Dev. Cell 12:17-30(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, SUBCELLULAR LOCATION, IDENTIFICATION BY MASS SPECTROMETRY, INTERACTION WITH MIS18A, IDENTIFICATION IN A COMPLEX CONTAINING MIS18A; MIS18B; MIS18BP1; RBBP7 AND RBBP4.
  8. "Functional genomics identifies a Myb domain-containing protein family required for assembly of CENP-A chromatin."
    Maddox P.S., Hyndman F., Monen J., Oegema K., Desai A.
    J. Cell Biol. 176:757-763(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, SUBCELLULAR LOCATION.
  9. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-110; THR-653; THR-821; SER-824; SER-1008; SER-1086; THR-1087; THR-1089 AND SER-1104, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  10. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
    Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S.
    Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  11. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
    Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
    Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1008 AND SER-1104, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Leukemic T-cell.
  12. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
    Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
    Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-653; SER-860; SER-1008; SER-1104 AND SER-1116, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  13. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
    Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
    Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-135; SER-172; SER-299; THR-653; SER-772; SER-773; SER-1008; SER-1104 AND SER-1116, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  14. "Solution structure of RSGI RUH-022, a Myb DNA-binding domain in human cDNA."
    RIKEN structural genomics initiative (RSGI)
    Submitted (NOV-2004) to the PDB data bank
    Cited for: STRUCTURE BY NMR OF 877-936.

Entry informationi

Entry nameiM18BP_HUMAN
AccessioniPrimary (citable) accession number: Q6P0N0
Secondary accession number(s): D3DSA7
, Q86V14, Q96PY4, Q9NUR5, Q9Y4X9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 21, 2005
Last sequence update: July 5, 2004
Last modified: October 29, 2014
This is version 109 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Human chromosome 14
    Human chromosome 14: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  5. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3