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Protein

Solute carrier family 25 member 33

Gene

slc25a33

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Mitochondrial transporter that imports/exports pyrimidine nucleotides into and from mitochondria which participates in dendritic cell endocytosis.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTransport

Names & Taxonomyi

Protein namesi
Recommended name:
Solute carrier family 25 member 33
Gene namesi
ORF Names:zgc:65787
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 23

Organism-specific databases

ZFINiZDB-GENE-040426-2183. slc25a33.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei7 – 27Helical; Name=1Sequence analysisAdd BLAST21
Transmembranei44 – 58Helical; Name=2Sequence analysisAdd BLAST15
Transmembranei114 – 134Helical; Name=3Sequence analysisAdd BLAST21
Transmembranei183 – 203Helical; Name=4Sequence analysisAdd BLAST21
Transmembranei226 – 246Helical; Name=5Sequence analysisAdd BLAST21
Transmembranei291 – 311Helical; Name=6Sequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002917871 – 314Solute carrier family 25 member 33Add BLAST314

Proteomic databases

PaxDbiQ6P036.

Expressioni

Gene expression databases

BgeeiENSDARG00000039931.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000058406.

Structurei

3D structure databases

ProteinModelPortaliQ6P036.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati4 – 111Solcar 1Add BLAST108
Repeati119 – 206Solcar 2Add BLAST88
Repeati224 – 308Solcar 3Add BLAST85

Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0757. Eukaryota.
ENOG410XS20. LUCA.
GeneTreeiENSGT00550000074670.
HOGENOMiHOG000188210.
HOVERGENiHBG059891.
InParanoidiQ6P036.
KOiK15116.
OMAiTHVAVQF.
OrthoDBiEOG091G0BCW.
PhylomeDBiQ6P036.
TreeFamiTF314220.

Family and domain databases

Gene3Di1.50.40.10. 1 hit.
InterProiView protein in InterPro
IPR002067. Mit_carrier.
IPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom.
PfamiView protein in Pfam
PF00153. Mito_carr. 3 hits.
PRINTSiPR00926. MITOCARRIER.
SUPFAMiSSF103506. SSF103506. 1 hit.
PROSITEiView protein in PROSITE
PS50920. SOLCAR. 3 hits.

Sequencei

Sequence statusi: Complete.

Q6P036-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQKDTLLHL FAGGCGGTVG AIMTCPLEVL KTRLQSSGLT LRPVFQVQLG
60 70 80 90 100
TLNGAGVIRP GSVTPGLLQV LRSILEKEGP RSLFRGLGPN LVGVAPSRAI
110 120 130 140 150
YFAAYSKSKE TFNGIFVPNS GVVHMSSAGF AAFITNSLMN PIWMVKTRMQ
160 170 180 190 200
LEKKARGEKK MNALQCARYV YKTEGMRGFY RGLTASYAGI SETMICFLIY
210 220 230 240 250
ETLKKYLAQS RFTTPDTDND KGASDFLGLM FAAAFAKGCA SCIAYPHEVI
260 270 280 290 300
RTRLREEGSK YKYFFQTARL VAVEEGYAAF YRGLIPQLIR QIPNTAIVLS
310
TYELIVHLLA EPSK
Length:314
Mass (Da):34,488
Last modified:July 5, 2004 - v1
Checksum:iB17F45B8DC39FBA2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC065854 mRNA. Translation: AAH65854.1.
BC056716 mRNA. Translation: AAH56716.1.
RefSeqiNP_998322.1. NM_213157.1.
UniGeneiDr.76663.

Genome annotation databases

EnsembliENSDART00000058407; ENSDARP00000058406; ENSDARG00000039931.
GeneIDi406436.
KEGGidre:406436.

Similar proteinsi

Entry informationi

Entry nameiS2533_DANRE
AccessioniPrimary (citable) accession number: Q6P036
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: July 5, 2004
Last modified: July 5, 2017
This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families