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Protein

ADP-ribosylation factor-like protein 8B-A

Gene

arl8ba

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

May play a role in lysosome motility. May play a role in chromosome segregation.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi29 – 35GTPBy similarity7
Nucleotide bindingi71 – 75GTPBy similarity5
Nucleotide bindingi130 – 133GTPBy similarity4

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, Chromosome partition, Mitosis
LigandGTP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
ADP-ribosylation factor-like protein 8B-A
Gene namesi
Name:arl8ba
Synonyms:arl8b
ORF Names:zgc:77187
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 6

Organism-specific databases

ZFINiZDB-GENE-030131-9370 arl8ba

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Intramembranei1 – 19Note=Mediates targeting to membranesBy similarityAdd BLAST19

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton, Endosome, Lysosome, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002329261 – 186ADP-ribosylation factor-like protein 8B-AAdd BLAST186

Proteomic databases

PaxDbiQ6NZW8
PRIDEiQ6NZW8

Expressioni

Gene expression databases

BgeeiENSDARG00000006915
ExpressionAtlasiQ6NZW8 baseline

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000019311

Structurei

3D structure databases

ProteinModelPortaliQ6NZW8
SMRiQ6NZW8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the small GTPase superfamily. Arf family.Curated

Phylogenomic databases

eggNOGiKOG0075 Eukaryota
ENOG410XNUK LUCA
GeneTreeiENSGT00780000121855
HOGENOMiHOG000163692
HOVERGENiHBG105214
InParanoidiQ6NZW8
KOiK07955
OMAiFFQSGQF
OrthoDBiEOG091G0USZ
PhylomeDBiQ6NZW8
TreeFamiTF105470

Family and domain databases

InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR005225 Small_GTP-bd_dom
IPR024156 Small_GTPase_ARF
IPR006689 Small_GTPase_ARF/SAR
PfamiView protein in Pfam
PF00025 Arf, 1 hit
PRINTSiPR00328 SAR1GTPBP
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00231 small_GTP, 1 hit
PROSITEiView protein in PROSITE
PS51417 ARF, 1 hit

Sequencei

Sequence statusi: Complete.

Q6NZW8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLALINRLLD WFKSLFWKEE MELTLVGLQY SGKTTFVNVI ASGQFSEDMI
60 70 80 90 100
PTVGFNMRKV TKGNVTIKIW DIGGQPRFRS MWERYCRGVN AIVYMVDAAD
110 120 130 140 150
REKVEASRNE LHNLLDKPQL QGIPVLVLGN KRDLPNALDE KQLIEKMNLA
160 170 180
AIQDREICCY SISCKEKDNI DITLQWLIQH SKSRRS
Length:186
Mass (Da):21,494
Last modified:July 5, 2004 - v1
Checksum:i64127071D299D167
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC065942 mRNA Translation: AAH65942.1
RefSeqiNP_991129.1, NM_205566.1
UniGeneiDr.78116

Genome annotation databases

EnsembliENSDART00000014552; ENSDARP00000019311; ENSDARG00000006915
GeneIDi337424
KEGGidre:337424

Similar proteinsi

Entry informationi

Entry nameiAR8BA_DANRE
AccessioniPrimary (citable) accession number: Q6NZW8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 18, 2006
Last sequence update: July 5, 2004
Last modified: June 20, 2018
This is version 116 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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