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Protein

ADP-ribosylation factor-like protein 8B-A

Gene

arl8ba

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

May play a role in lysosome motility. May play a role in chromosome segregation.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi29 – 35GTPBy similarity7
Nucleotide bindingi71 – 75GTPBy similarity5
Nucleotide bindingi130 – 133GTPBy similarity4

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, Chromosome partition, Mitosis
LigandGTP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
ADP-ribosylation factor-like protein 8B-A
Gene namesi
Name:arl8ba
Synonyms:arl8b
ORF Names:zgc:77187
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 6

Organism-specific databases

ZFINiZDB-GENE-030131-9370. arl8ba.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Intramembranei1 – 19Note=Mediates targeting to membranesBy similarityAdd BLAST19

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton, Endosome, Lysosome, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002329261 – 186ADP-ribosylation factor-like protein 8B-AAdd BLAST186

Proteomic databases

PaxDbiQ6NZW8.
PRIDEiQ6NZW8.

Expressioni

Gene expression databases

BgeeiENSDARG00000006915.
ExpressionAtlasiQ6NZW8. baseline.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000019311.

Structurei

3D structure databases

ProteinModelPortaliQ6NZW8.
SMRiQ6NZW8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the small GTPase superfamily. Arf family.Curated

Phylogenomic databases

eggNOGiKOG0075. Eukaryota.
ENOG410XNUK. LUCA.
GeneTreeiENSGT00890000139352.
HOGENOMiHOG000163692.
HOVERGENiHBG105214.
InParanoidiQ6NZW8.
KOiK07955.
OMAiFFQSGQF.
OrthoDBiEOG091G0USZ.
PhylomeDBiQ6NZW8.
TreeFamiTF105470.

Family and domain databases

InterProiView protein in InterPro
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR024156. Small_GTPase_ARF.
IPR006689. Small_GTPase_ARF/SAR.
PfamiView protein in Pfam
PF00025. Arf. 1 hit.
PRINTSiPR00328. SAR1GTPBP.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.
PROSITEiView protein in PROSITE
PS51417. ARF. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6NZW8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLALINRLLD WFKSLFWKEE MELTLVGLQY SGKTTFVNVI ASGQFSEDMI
60 70 80 90 100
PTVGFNMRKV TKGNVTIKIW DIGGQPRFRS MWERYCRGVN AIVYMVDAAD
110 120 130 140 150
REKVEASRNE LHNLLDKPQL QGIPVLVLGN KRDLPNALDE KQLIEKMNLA
160 170 180
AIQDREICCY SISCKEKDNI DITLQWLIQH SKSRRS
Length:186
Mass (Da):21,494
Last modified:July 5, 2004 - v1
Checksum:i64127071D299D167
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC065942 mRNA. Translation: AAH65942.1.
RefSeqiNP_991129.1. NM_205566.1.
UniGeneiDr.78116.

Genome annotation databases

EnsembliENSDART00000014552; ENSDARP00000019311; ENSDARG00000006915.
GeneIDi337424.
KEGGidre:337424.

Similar proteinsi

Entry informationi

Entry nameiAR8BA_DANRE
AccessioniPrimary (citable) accession number: Q6NZW8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 18, 2006
Last sequence update: July 5, 2004
Last modified: August 30, 2017
This is version 113 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families