Q6NZR5 (Q6NZR5_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Protein Skiv2l Ensembl ENSMUSP00000036265

Submitted name:
Superkiller viralicidic activity 2-like (S. cerevisiae) EMBL AAH65999.1

Gene names

Name:

Skiv2l Ensembl ENSMUSP00000036265 MGI 1099835 EMBL AAH65999.1

Organism

Mus musculus (Mouse) [Reference proteome] EMBL AAH65999.1

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	1244 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Helicase RuleBase RU000452 Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	Ski complex Inferred from electronic annotation. Source: Compara
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ATP-dependent helicase activity Inferred from electronic annotation. Source: InterPro nucleic acid binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q6NZR5 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: C6D0208F9265D628	FASTA	1,244	137,524
	10 20 30 40 50 60 MMETERLVLP PLDPLNLPLR ALEVGCTGRW ELLNVPGPPE STLPHGLPPC APDLCQEAEQ 70 80 90 100 110 120 LFLSSPAWLP LHGVEHSARK WQRKTDPWSL LAAVETPVPS DLQAQRHPTT GHILGYKEVL 130 140 150 160 170 180 LENTNLSATT SLSLRRPPGP ASQSLWGNPT QYPFWPGGMD EPSITDLHTR EEAEEEIDFE 190 200 210 220 230 240 KDLLTVPPGF KKGVDFAPKD HPAPVPGLLS LSRLLEPLDL SGGDEDEGEA AGGPRGDNAS 250 260 270 280 290 300 PSPSGTPLVR ASSLEDLVLK EAATVVSTPE PPKPPPQEQW AVPVDVTSPV GDFYRLIPQP 310 320 330 340 350 360 AFQWAFEPDV FQKQAILHLE QHDSVFVAAH TSAGKTVVAE YAIALAQKHM TRTIYTSPIK 370 380 390 400 410 420 ALSNQKFRDF RNTFGDVGLL TGDVQLHPEA SCLIMTTEIL RSMLYSGSDV IRDLEWVIFD 430 440 450 460 470 480 EVHYINDAER GVVWEEVLIM LPEHVSIILL SATVPNALEF ADWIGRLKRR QIYVISTVAR 490 500 510 520 530 540 PVPLEHYLFT GNSPKTQGEL FLLLDSRGAF HTQGYYAAVE AKKERMSKHA QTFGAKQPTH 550 560 570 580 590 600 QGGPAQDRGV YLSLLASLRT RAQLPVVVFT FSRGRCDEQA SGLTSLDLTT SSEKSEIHLF 610 620 630 640 650 660 LQRCLARLRG SDRQLPQVLH MSELLRRGLG VHHSGILPIL KEIVEMLFSR GLVKVLFATE 670 680 690 700 710 720 TFAMGVNMPA RTVVFDSMRK HDGSTFRDLL PGEYVQMAGR AGRRGLDPTG TVILLCKGRV 730 740 750 760 770 780 PEMADLHRMM MGKPSQLQSQ FRLTYTMILN LLRVDALRVE DMMKRSFSEF PSRKDSKAHE 790 800 810 820 830 840 QALADLTKRL GALEEPDVTG QLADLPEYYS WAEELTETQN MIQRRIMESV NGLKSLSVGR 850 860 870 880 890 900 VVVVKNEEHH NALGVILQVS SNSTSRVFTT LVLCDKPVVS DNPRDKGPAT PDVPHPDDLI 910 920 930 940 950 960 GFKLFLPEGP CEHTVAKLQP GDVAAISTKV LRVNGEKISE DFSKRQQPKF RKDPPLAAVT 970 980 990 1000 1010 1020 TAVQELLRLA QSYPAGPPTL DPINDLQLKD VAVVEGGLRA RKLEELIRGA QCVHSPRFPA 1030 1040 1050 1060 1070 1080 QYVKLRERMQ IQKEMERLRF LLSDQSLLLL PEYHQRVEVL RTLGYVDEAG TVKLAGRVAC 1090 1100 1110 1120 1130 1140 AMSSHELLLT ELMFDNALSA LRPEEIAALL SGLVCQSPGD PGDQLPSTLK QGVERVKAVA 1150 1160 1170 1180 1190 1200 KRIGEVQVAC GLNQTVEEFV GELNFGLVEV VYEWARGMPF SELAGLSGTP EGLVVRCIQR 1210 1220 1230 1240 LAEMCRSLRG AARLVGEPVL GAKMETAATL LRRDIVFAAS LYTQ

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M. , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J. Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: C57BL/6 EMBL AAH65999.1. Tissue: Brain EMBL AAH65999.1.
[2]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J Ensembl ENSMUSP00000036265.
[3]	Ensembl Submitted (FEB-2012) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000036265.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CT025759 Genomic DNA. No translation available. BC065999 mRNA. Translation: AAH65999.1.
IPI	IPI00454140.
RefSeq	NP_067312.2. NM_021337.2.
UniGene	Mm.18845.
3D structure databases
SMR	Q6NZR5. Positions 277-1242.
ModBase	Search...
Protein-protein interaction databases
STRING	10090.ENSMUSP00000036265.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000046022; ENSMUSP00000036265; ENSMUSG00000040356.
GeneID	108077.
KEGG	mmu:108077.
UCSC	uc008cds.1. mouse.
Organism-specific databases
CTD	6499.
MGI	MGI:1099835. Skiv2l.
Phylogenomic databases
GeneTree	ENSGT00690000102154.
HOVERGEN	HBG060025.
InParanoid	Q6NZR5.
KO	K12599.
OMA	TRLDETC.
Gene expression databases
Genevestigator	Q6NZR5.
Family and domain databases
InterPro	IPR011545. DNA/RNA_helicase_DEAD/DEAH_N. IPR012961. DSH_C. IPR014001. Helicase_ATP-bd. IPR001650. Helicase_C. IPR027417. P-loop_NTPase. IPR016438. RNA_helicase_ATP-dep_SK12/DOB1. IPR025696. rRNA_proc-arch_dom. [Graphical view]
Pfam	PF00270. DEAD. 1 hit. PF08148. DSHCT. 1 hit. PF00271. Helicase_C. 1 hit. PF13234. rRNA_proc-arch. 1 hit. [Graphical view]
PIRSF	PIRSF005198. Antiviral_helicase_SKI2. 1 hit.
SMART	SM00487. DEXDc. 1 hit. SM00490. HELICc. 1 hit. [Graphical view]
SUPFAM	SSF52540. SSF52540. 1 hit.
PROSITE	PS51192. HELICASE_ATP_BIND_1. 1 hit. PS51194. HELICASE_CTER. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	SKIV2L. mouse.
NextBio	360008.
SOURCE	Search...

Entry information

Entry name

Q6NZR5_MOUSE

Accession

Primary (citable) accession number: Q6NZR5

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	May 29, 2013
This is version 85 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)