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Protein
Submitted name:

DEAH (Asp-Glu-Ala-His) box polypeptide 37

Gene

Dhx37

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseSAAS annotation
LigandATP-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-MMU-6791226. Major pathway of rRNA processing in the nucleolus and cytosol.

Names & Taxonomyi

Protein namesi
Submitted name:
DEAH (Asp-Glu-Ala-His) box polypeptide 37Imported
Gene namesi
Name:Dhx37Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 5

Organism-specific databases

MGIiMGI:3028576. Dhx37.

Subcellular locationi

GO - Cellular componenti

Expressioni

Gene expression databases

BgeeiENSMUSG00000029480.

Interactioni

Protein-protein interaction databases

IntActiQ6NZL1. 1 interactor.
STRINGi10090.ENSMUSP00000131734.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini258 – 425Helicase ATP-bindingInterPro annotationAdd BLAST168
Domaini548 – 709Helicase C-terminalInterPro annotationAdd BLAST162

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili76 – 99Sequence analysisAdd BLAST24

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0926. Eukaryota.
COG1643. LUCA.
GeneTreeiENSGT00550000074985.
HOGENOMiHOG000201240.
HOVERGENiHBG051356.
KOiK14780.
OMAiKIHRMLP.
OrthoDBiEOG091G02IP.
TreeFamiTF105654.

Family and domain databases

InterProiView protein in InterPro
IPR011545. DEAD/DEAH_box_helicase_dom.
IPR011709. DUF1605.
IPR007502. Helicase-assoc_dom.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
PfamiView protein in Pfam
PF00270. DEAD. 1 hit.
PF04408. HA2. 1 hit.
PF00271. Helicase_C. 1 hit.
PF07717. OB_NTP_bind. 1 hit.
SMARTiView protein in SMART
SM00487. DEXDc. 1 hit.
SM00847. HA2. 1 hit.
SM00490. HELICc. 1 hit.
SUPFAMiSSF52540. SSF52540. 2 hits.
PROSITEiView protein in PROSITE
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6NZL1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKLRRRYNV KGRLQADPRP AKGPEAPPVR LELEGKDVLK GVDESNVLVL
60 70 80 90 100
PGKRKKKTKA PPPSKKERKP LTKKERKVLQ KVLEQKEKKS QRAELLQKLS
110 120 130 140 150
EVQVSEAEMS LFYTTAKLGT GDRMYHIKER KSGQPAARGQ EKVSSLSGAH
160 170 180 190 200
RKRHRSSSTE EDSESSEDSE PEEATADQPR TSTGTEPVHP PPAPSGINSP
210 220 230 240 250
APTPQPPPSG ISAPPKTPAS APPPPVAKPA VFIPVNRTPE MQEERLKLPI
260 270 280 290 300
LAEEQAIMEA VAEHPIVIVC GETGSGKTTQ VPQFLYEAGY SSEDSIIGVT
310 320 330 340 350
EPRRVAAVAM SQRVAKEMNL SHRVVSYQIR YEGNVTEETR IKFMTDGVLL
360 370 380 390 400
KEIQKDFLLL KYKVVIIDEA HERSVYTDIL LGLLSRIVAL RAKRHLPLKL
410 420 430 440 450
LIMSATLRVE DFTQNQRLFT TPPPVIKVES RQFPVTVHFN KRTPLDDYSG
460 470 480 490 500
ECFRKVCKIH RMLPAGGILV FLTGQAEVHA LCRRLRKAFP FRCSQPQEKE
510 520 530 540 550
EDSAEGMRRF KKSRTRARKA QAMALPQINL DNYSVLPAGE GDEDREAEMD
560 570 580 590 600
DEEEALGSDL DLDLGDSEAN EGEQPDASLP LHVLPLYSLL APEKQAQVFK
610 620 630 640 650
PPPEGTRLCV VATNVAETSL TIPGIKYVVD CGKVKKRYYD RVTGVSSFRV
660 670 680 690 700
TWVSQASADQ RAGRAGRTEP GHCYRLYSSA VFGDFEQFPP PEITRRPVED
710 720 730 740 750
LILQMKALSI EKVINFPFPT PPSVEALVAA EELLVALGAL QAPPKQERMK
760 770 780 790 800
KLQMSQLSCP ITALGRTMST FPVAPRYAKM LALSQQHGCL PYTIAIVAAM
810 820 830 840 850
TVRELFEELD RPAASEKELA ELKGRRARVA QMKRTWAGQG PSLKLGDLMV
860 870 880 890 900
LLGAVGACEY AGCSPQFCQA NGLRYKAMLE IRRLRGQLTT AVNAVCPEAG
910 920 930 940 950
LFLDPKMQPP TESQVTYLRQ IMAAGLGDHL ARRVQSEDLL DPKWKNAYKT
960 970 980 990 1000
PLLDDPVFIH PSSVLFKELP EFVVYQEIVE TTKMYMKGVS TVEIQWIPSL
1010 1020 1030 1040 1050
LPSYCQFDAP LEEPAPSYCP ESGQVLCHRA SVFYRVGWPL PAVQVDFPEG
1060 1070 1080 1090 1100
IDRYKYFAKF LLEGQVFRKL ASFKSCLLSS PSTMLKTWAR LQPRTETLLR
1110 1120 1130 1140 1150
ALVAHKADSR DSLLAAWKKN PKYLLAEYCE WLPKAMHSDV EKNWPPTTDS
Length:1,150
Mass (Da):128,328
Last modified:July 5, 2004 - v1
Checksum:i949091B53FFC1E9C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC138613 Genomic DNA. No translation available.
BC066077 mRNA. Translation: AAH66077.1.
BC080298 mRNA. Translation: AAH80298.1.
RefSeqiNP_976064.1. NM_203319.1.
UniGeneiMm.296385.

Genome annotation databases

EnsembliENSMUST00000169485; ENSMUSP00000131734; ENSMUSG00000029480.
GeneIDi208144.
KEGGimmu:208144.
UCSCiuc008zrq.1. mouse.

Similar proteinsi

Entry informationi

Entry nameiQ6NZL1_MOUSE
AccessioniPrimary (citable) accession number: Q6NZL1
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: August 30, 2017
This is version 122 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported