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Protein
Submitted name:

Tlk2 protein

Gene

Tlk2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Tlk2 proteinImported
Gene namesi
Name:Tlk2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1346023. Tlk2.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

GenevisibleiQ6NZC4. MM.

Structurei

3D structure databases

ProteinModelPortaliQ6NZC4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini400 – 657Protein kinaseInterPro annotationAdd BLAST258

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili278 – 305Sequence analysisAdd BLAST28
Coiled coili351 – 385Sequence analysisAdd BLAST35

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

HOGENOMiHOG000259522.
HOVERGENiHBG007938.

Family and domain databases

InterProiView protein in InterPro
IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
IPR027086. TLK2.
PANTHERiPTHR22974:SF27. PTHR22974:SF27. 1 hit.
PfamiView protein in Pfam
PF00069. Pkinase. 1 hit.
SMARTiView protein in SMART
SM00220. S_TKc. 1 hit.
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiView protein in PROSITE
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q6NZC4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
AERSAAGSGR GPSREESGAA AAAEMMEELH SLDPRRQELL EARFTGVGVS
60 70 80 90 100
KGPLNSESSN QSLCSVGSLS DKEVETPEKK QNDQRNRKRK AEPYDTSQGK
110 120 130 140 150
GTPRGHKISD YFERRAEQPL YGLDGSAAKE ASEEQSALPT LMSVMLAKPR
160 170 180 190 200
LDTEQLAPRG AGLCFTFVSS DLTIEKISAL ENSKNSDLEK KEGRIDDLLR
210 220 230 240 250
ANCDLRRQID EQQKMLEKYK ERLNRCVTMS KKLLIEKSKQ EKMACRDKSM
260 270 280 290 300
QDRLRLGHFT TVRHGASFTE QWTDGYAFQN LIKQQERINS QREEIERQRK
310 320 330 340 350
MLAKRKPPAM GQAPPATNEQ KQRKSKTNGA ENETLTLAEY HEQEEIFKLR
360 370 380 390 400
LGHLKKEEAE IQAELERLER VRNLHIRELK RIHNEDNSQF KDHPTLNDRY
410 420 430 440 450
LLLHLLGRGG FSEVYKAFDL TEQRYVAVKI HQLNKNWRDE KKENYHKHAC
460 470 480 490 500
REYRIHKELD HPRIVKLYDY FSLDTDSFCT VLEYCEGNDL DFYLKQHKLM
510 520 530 540 550
SEKEARSIIM QIVNALKYLN EIKPPIIHYD LKPGNILLVN GTACGEIKIT
560 570 580 590 600
DFGLSKIMDD DSYNSVDGME LTSQGAGTYW YLPPECFVVG KEPPKISNKV
610 620 630 640 650
DVWSVGVIFY QCLYGRKVRK KAVEQPGAIP TTSLGFFFAV NHWNPESSGL

KKIQTSQ
Length:657
Mass (Da):75,355
Last modified:July 5, 2004 - v1
Checksum:i97E9E7C78C5F5124
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC066198 mRNA. Translation: AAH66198.1.
RefSeqiNP_001281259.1. NM_001294330.1.
NP_001281263.1. NM_001294334.1.
UniGeneiMm.126976.

Genome annotation databases

GeneIDi24086.

Similar proteinsi

Entry informationi

Entry nameiQ6NZC4_MOUSE
AccessioniPrimary (citable) accession number: Q6NZC4
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: August 30, 2017
This is version 93 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)