Unreviewed, UniProtKB/TrEMBL Q6NZ77 (Q6NZ77_HUMAN)

Names and origin

Protein names

Submitted name:
    Interleukin 4, isoform 1 EMBL AAH66277.1

Gene names

Name:

IL4 EMBL AAH66277.1

Organism

Homo sapiens (Human) EMBL AAH66277.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	153 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level.

Ontologies

Gene Ontology (GO)
Biological process	cholesterol metabolic process Inferred from electronic annotation. Source: Compara immune response Inferred from electronic annotation. Source: InterPro negative regulation of apoptosis Inferred from electronic annotation. Source: Compara negative regulation of osteoclast differentiation Inferred from electronic annotation. Source: Compara positive regulation of B cell proliferation Inferred from electronic annotation. Source: Compara positive regulation of MHC class II biosynthetic process Inferred from electronic annotation. Source: Compara positive regulation of activated T cell proliferation Inferred from electronic annotation. Source: Compara positive regulation of gene-specific transcription Inferred from electronic annotation. Source: Compara positive regulation of isotype switching to IgE isotypes Inferred from electronic annotation. Source: Compara positive regulation of isotype switching to IgG isotypes Inferred from electronic annotation. Source: Compara positive regulation of transcription factor activity Inferred from electronic annotation. Source: Compara positive regulation of transcription from RNA polymerase II promoter Inferred from electronic annotation. Source: Compara positive regulation of tyrosine phosphorylation of Stat5 protein Inferred from electronic annotation. Source: Compara
Cellular component	extracellular space Inferred from electronic annotation. Source: Compara
Molecular function	cytokine activity Inferred from electronic annotation. Source: Compara growth factor activity Inferred from electronic annotation. Source: InterPro interleukin-4 receptor binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q6NZ77-1 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 8725AA24B35805F7	FASTA	153	17,476
	10 20 30 40 50 60 MGLTSQLLPP LFFLLACAGN FVHGHKCDIT LQEIIKTLNS LTEQKTLCTE LTVTDIFAAS 70 80 90 100 110 120 KNTTEKETFC RAATVLRQFY SHHEKDTRCL GATAQQFHRH KQPIRFLKRL DRNLWGLAGL 130 140 150 NSCPVKEANQ STLENFLERL KTIMREKYSK CSS

References

[1]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: PCR rescued clones EMBL AAH66277.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC066277 mRNA. Translation: AAH66277.1.
IPI	IPI00007081.
UniGene	Hs.73917
3D structure databases
HSSP	HSSP built from PDB template 1BBN based on UniProtKB P05112.
SMR	Q6NZ77. Positions 25-153.
ModBase	Search...
Protein-protein interaction databases
STRING	Q6NZ77.
Genome annotation databases
Ensembl	ENST00000231449; ENSP00000231449; ENSG00000113520; Homo sapiens. [Genome view]
Organism-specific databases
HGNC	HGNC:6014. IL4.
GenAtlas	Search...
Phylogenomic databases
HOVERGEN	Q6NZ77.
Gene expression databases
ArrayExpress	Q6NZ77.
Bgee	Q6NZ77.
Family and domain databases
InterPro	IPR009079. 4_helix_cytokine-like_core. IPR018096. Interleukin-4/-13_CS. IPR002354. Interleukin_4. IPR001325. Interleukin_4_13. [Graphical view]
PANTHER	PTHR11456. Interleukin_4. 1 hit.
Pfam	PF00727. IL4. 1 hit. [Graphical view]
PIRSF	PIRSF001941. Interleukin_4. 1 hit.
PRINTS	PR00431. INTERLEUKIN4.
SMART	SM00190. IL4_13. 1 hit. [Graphical view]
PROSITE	PS00838. INTERLEUKIN_4_13. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q6NZ77_HUMAN

Accession

Primary (citable) accession number: Q6NZ77

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	January 19, 2010
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.