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Protein

ATP synthase-coupling factor 6, mitochondrial

Gene

ATP5J

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Hydrogen ion transportUniRule annotation, Ion transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
ATP synthase-coupling factor 6, mitochondrialUniRule annotation
Short name:
ATPase subunit F6UniRule annotation
Gene namesi
Name:ATP5JImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

  • Mitochondrion UniRule annotation
  • Mitochondrion inner membrane UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membraneUniRule annotation

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA25137.

PTM / Processingi

Proteomic databases

PaxDbiQ6NZ59.
PeptideAtlasiQ6NZ59.
PRIDEiQ6NZ59.

Expressioni

Gene expression databases

GenevisibleiQ6NZ59. HS.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000389649.

Family & Domainsi

Sequence similaritiesi

Belongs to the eukaryotic ATPase subunit F6 family.UniRule annotation

Phylogenomic databases

eggNOGiKOG4634. Eukaryota.
ENOG41122G1. LUCA.
HOVERGENiHBG062261.
KOiK02131.

Family and domain databases

InterProiIPR008387. ATPase_F0-cplx_f6su_mt.
IPR016349. ATPase_F0-cplx_f6su_mt_subgr.
[Graphical view]
PANTHERiPTHR12441. PTHR12441. 1 hit.
PfamiPF05511. ATP-synt_F6. 1 hit.
[Graphical view]
PIRSFiPIRSF002455. ATP_synthase_coupling_factor_6. 1 hit.
SUPFAMiSSF111357. SSF111357. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6NZ59-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MILQRLFRFS SVIRSAVSVH LRRNIGVTAV AFNKELDPIQ KLFVDKIREY
60 70 80 90 100
KSKRQTSGGP VDASSEYQQE LERELFKLKQ MFGNADMNTF HTFKFEDPKF

EVIEKPQA
Length:108
Mass (Da):12,628
Last modified:July 5, 2004 - v1
Checksum:iEDD2CDCF01A10F17
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC066310 mRNA. Translation: AAH66310.1.
RefSeqiNP_001003696.1. NM_001003696.1.
NP_001003697.1. NM_001003697.1.
NP_001003701.1. NM_001003701.1.
NP_001003703.1. NM_001003703.1.
NP_001676.2. NM_001685.4.
UniGeneiHs.246310.

Genome annotation databases

GeneIDi522.
KEGGihsa:522.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC066310 mRNA. Translation: AAH66310.1.
RefSeqiNP_001003696.1. NM_001003696.1.
NP_001003697.1. NM_001003697.1.
NP_001003701.1. NM_001003701.1.
NP_001003703.1. NM_001003703.1.
NP_001676.2. NM_001685.4.
UniGeneiHs.246310.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000389649.

Proteomic databases

PaxDbiQ6NZ59.
PeptideAtlasiQ6NZ59.
PRIDEiQ6NZ59.

Protocols and materials databases

DNASUi522.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi522.
KEGGihsa:522.

Organism-specific databases

CTDi522.
PharmGKBiPA25137.

Phylogenomic databases

eggNOGiKOG4634. Eukaryota.
ENOG41122G1. LUCA.
HOVERGENiHBG062261.
KOiK02131.

Miscellaneous databases

ChiTaRSiATP5J. human.
GenomeRNAii522.

Gene expression databases

GenevisibleiQ6NZ59. HS.

Family and domain databases

InterProiIPR008387. ATPase_F0-cplx_f6su_mt.
IPR016349. ATPase_F0-cplx_f6su_mt_subgr.
[Graphical view]
PANTHERiPTHR12441. PTHR12441. 1 hit.
PfamiPF05511. ATP-synt_F6. 1 hit.
[Graphical view]
PIRSFiPIRSF002455. ATP_synthase_coupling_factor_6. 1 hit.
SUPFAMiSSF111357. SSF111357. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ6NZ59_HUMAN
AccessioniPrimary (citable) accession number: Q6NZ59
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: July 6, 2016
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.