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Protein

ATP synthase-coupling factor 6, mitochondrial

Gene

ATP5J

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processHydrogen ion transportUniRule annotation, Ion transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
ATP synthase-coupling factor 6, mitochondrialUniRule annotation
Short name:
ATPase subunit F6UniRule annotation
Gene namesi
Name:ATP5JImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membraneUniRule annotation

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA25137

PTM / Processingi

Proteomic databases

PeptideAtlasiQ6NZ59
PRIDEiQ6NZ59

Expressioni

Gene expression databases

GenevisibleiQ6NZ59 HS

Family & Domainsi

Sequence similaritiesi

Belongs to the eukaryotic ATPase subunit F6 family.UniRule annotation

Phylogenomic databases

eggNOGiKOG4634 Eukaryota
ENOG41122G1 LUCA
HOVERGENiHBG062261
KOiK02131

Family and domain databases

InterProiView protein in InterPro
IPR008387 ATP_synth_f6_mt
IPR036204 ATP_synth_f6_sf_mt
PANTHERiPTHR12441 PTHR12441, 1 hit
PfamiView protein in Pfam
PF05511 ATP-synt_F6, 1 hit
PIRSFiPIRSF002455 ATP_synthase_coupling_factor_6, 1 hit
SUPFAMiSSF111357 SSF111357, 1 hit

Sequencei

Sequence statusi: Complete.

Q6NZ59-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MILQRLFRFS SVIRSAVSVH LRRNIGVTAV AFNKELDPIQ KLFVDKIREY
60 70 80 90 100
KSKRQTSGGP VDASSEYQQE LERELFKLKQ MFGNADMNTF HTFKFEDPKF

EVIEKPQA
Length:108
Mass (Da):12,628
Last modified:July 5, 2004 - v1
Checksum:iEDD2CDCF01A10F17
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC066310 mRNA Translation: AAH66310.1
RefSeqiNP_001003696.1, NM_001003696.1
NP_001003697.1, NM_001003697.1
NP_001003701.1, NM_001003701.1
NP_001003703.1, NM_001003703.1
NP_001676.2, NM_001685.4
UniGeneiHs.246310

Genome annotation databases

GeneIDi522
KEGGihsa:522

Similar proteinsi

Entry informationi

Entry nameiQ6NZ59_HUMAN
AccessioniPrimary (citable) accession number: Q6NZ59
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: April 25, 2018
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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