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Q6NXI4 (Q6NXI4_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 84. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
Gene names
Name:Rapgef2 EMBL AAH67056.1 MGI 2659071
OrganismMus musculus (Mouse) EMBL AAH67056.1
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length1511 AA.
Sequence statusFragment.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 PDZ (DHR) domain. RuleBase RU003354

Contains N-terminal Ras-GEF domain. SAAS SAAS000651

Contains Ras-GEF domain. SAAS SAAS000651

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue11 EMBL AAH67056.1

Sequences

Sequence LengthMass (Da)Tools
Q6NXI4 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: FC65F1077673A757

FASTA1,511168,517
        10         20         30         40         50         60 
LRGIFFYLEK EAFSTQEMAF LVRCYANCLQ PWSSKLPADF TKLHLTDSLH PQVTHVSSSH 

        70         80         90        100        110        120 
SGCSITSDSG SSSLSDIYQA TESEAGDMDL SGLPETAVDS EDDDDEEDIE RASDPLMSRD 

       130        140        150        160        170        180 
IVRDCLEKDP IDRTDDDIEQ LLEFMHQLPA FANMTMSVRR ELCAVMVFAV VERAGTIVLN 

       190        200        210        220        230        240 
DGEELDSWSV ILNGSVEVTY PDGKAEILCM GNSFGVSPTM DKEYMKGVMR TKVDDCQFVC 

       250        260        270        280        290        300 
IAQQDYCRIL NQVEKNMQKV EEEGEIVMVK EHRELDRTGT RKGHIVIKGT SERLTMHLVE 

       310        320        330        340        350        360 
EHSVVDPTFI EDFLLTYRTF LSSPMEVGKK LLEWFNDPSL RDKVTRVVLL WVNNHFNDFE 

       370        380        390        400        410        420 
GDPAMTRFLE EFENNLEREK MGGHLRLLNI ACAAKAKRRL MTLTKPSREA PLPFILLGGS 

       430        440        450        460        470        480 
EKGFGIFVDS VDSCSKATEA GLKRGDQILE VNGQNFENIQ LSKAMEILRN NTHLSITVKT 

       490        500        510        520        530        540 
NLFVFKELLT RLSEEKRNGA PHLPKIGDIK KASRYSIPDL AVDVEQVIGL EKVNKKSKAN 

       550        560        570        580        590        600 
TVGGRNKLKK ILDKTRISIL PQKPYNDIGI GQSQDDSIVG LRQTKHIPAA LPVSGTLSSS 

       610        620        630        640        650        660 
NPDLLQSHHR ILDFSTTPDL PDQVLRVFKA DQQSRYIMIS KDTTAKEVVI QAIREFAVTA 

       670        680        690        700        710        720 
TPEQYSLCEV SVTPEGVIKQ RRLPDQLSKL ADRIQLSGRY YLKNNMETET LCSDEDAQEL 

       730        740        750        760        770        780 
LRESQISLLQ LSTVEVATQL SMRNFELFRN IEPTEYIDDL FKLKSKTSCA NLKKFEEVIN 

       790        800        810        820        830        840 
QETFWVASEI LRETNQLKRM KIIKHFIKIA LHCRECKNFN SMFAIISGLN LAPVARLRTT 

       850        860        870        880        890        900 
WEKLPNKYEK LFQDLQDLFD PSRNMAKYRN VLSGQNLQPP VIPLFPVIKK DLTFLHEGND 

       910        920        930        940        950        960 
SKVDGLVNFE KLRMIAKEIR HVGRMASVNM DPALMFRTRK KKWRSLGSLS QGSANATVLD 

       970        980        990       1000       1010       1020 
VAQTGGHKKR VRRSSFLNAK KLYEDAQMAR KVKQYLSNLE LEMDEESLQT LSLQCEPATS 

      1030       1040       1050       1060       1070       1080 
TLPKNPGDKK PVKSETSPVA PRAGPQQKVQ PQQPLAQPQP PHKVSQGLQV PAVSLYPSRK 

      1090       1100       1110       1120       1130       1140 
KVPVKDLPPF GINSPQALKK ILSLSEEGSL ERHRKQAEDT ISNASSQLSS PPTSPQSSPR 

      1150       1160       1170       1180       1190       1200 
KGYALALSGT VDNFSDSGHS EISSRSSIVS NSSFDSVPVS LHDERRQRHS VSIVESNLGV 

      1210       1220       1230       1240       1250       1260 
GRMERRTLME PDQYSLGSYA PVSESRGLYA AATVISSPST EELSHDQGDR ASLDAADSGR 

      1270       1280       1290       1300       1310       1320 
GSWTSCSSGS HDNIQTIQHQ RSWETLPFGH THFDYSGDAA SIWASGGHMD QMMFSDHSTK 

      1330       1340       1350       1360       1370       1380 
YNRQNQSRES LEQAQSRASW ASSTGYWGED SEGDTGTIKR RGGKDVSAEA ESSSMVPVTT 

      1390       1400       1410       1420       1430       1440 
EEAKPVPMPA HIAVTPSTTK GLIARKEGRY REPPPTPPGY VGIPIADFPE GPCHPARKPP 

      1450       1460       1470       1480       1490       1500 
DYNVALQRSR MVARPTEAPA PGRTPPAAAA SRPGSKPQWH KPSDADPRLA PFQPQGFAGA 

      1510 
EEDEDEQVSA V 

« Hide

References

[1]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M. expand/collapse author list , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: C57BL/6 EMBL AAH67056.1.
Tissue: Brain EMBL AAH67056.1.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BC067056 mRNA. Translation: AAH67056.1.
RefSeqNP_001093094.2. NM_001099624.2.
UniGeneMm.31220.
Mm.462396.

3D structure databases

ProteinModelPortalQ6NXI4.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActQ6NXI4. 1 interaction.
STRING10090.ENSMUSP00000043884.

PTM databases

PhosphoSiteQ6NXI4.

Proteomic databases

PRIDEQ6NXI4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID76089.
KEGGmmu:76089.

Organism-specific databases

CTD9693.
MGIMGI:2659071. Rapgef2.

Phylogenomic databases

HOGENOMHOG000247009.
HOVERGENHBG056658.
InParanoidQ6NXI4.
KOK08018.

Gene expression databases

GenevestigatorQ6NXI4.

Family and domain databases

Gene3D1.10.840.10. 1 hit.
2.30.42.10. 1 hit.
2.60.120.10. 1 hit.
InterProIPR018490. cNMP-bd-like.
IPR000595. cNMP-bd_dom.
IPR001478. PDZ.
IPR000159. Ras-assoc.
IPR000651. Ras-like_Gua-exchang_fac_N.
IPR023578. Ras_GEF_dom.
IPR001895. RasGRF_CDC25.
IPR014710. RmlC-like_jellyroll.
IPR029071. Ubiquitin-rel_dom.
[Graphical view]
PfamPF00027. cNMP_binding. 1 hit.
PF00595. PDZ. 1 hit.
PF00788. RA. 1 hit.
PF00617. RasGEF. 1 hit.
PF00618. RasGEF_N. 1 hit.
[Graphical view]
SMARTSM00100. cNMP. 1 hit.
SM00228. PDZ. 1 hit.
SM00314. RA. 1 hit.
SM00147. RasGEF. 1 hit.
SM00229. RasGEFN. 1 hit.
[Graphical view]
SUPFAMSSF48366. SSF48366. 3 hits.
SSF50156. SSF50156. 1 hit.
SSF51206. SSF51206. 1 hit.
SSF54236. SSF54236. 1 hit.
PROSITEPS50042. CNMP_BINDING_3. 1 hit.
PS50106. PDZ. 1 hit.
PS50200. RA. 1 hit.
PS50009. RASGEF_CAT. 1 hit.
PS50212. RASGEF_NTER. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio344577.
SOURCESearch...

Entry information

Entry nameQ6NXI4_MOUSE
AccessionPrimary (citable) accession number: Q6NXI4
Entry history
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: June 11, 2014
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)