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Protein
Submitted name:

FLNA protein

Gene

FLNA

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
FLNA proteinImported
Gene namesi
Name:FLNAImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA28172.

PTM / Processingi

Proteomic databases

PaxDbiQ6NXF2.
PeptideAtlasiQ6NXF2.
PRIDEiQ6NXF2.

Expressioni

Gene expression databases

GenevisibleiQ6NXF2. HS.

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliQ6NXF2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati1 – 76FilaminPROSITE-ProRule annotationAdd BLAST76
Repeati115 – 196FilaminPROSITE-ProRule annotationAdd BLAST82
Repeati196 – 288FilaminPROSITE-ProRule annotationAdd BLAST93
Repeati286 – 375FilaminPROSITE-ProRule annotationAdd BLAST90
Repeati378 – 470FilaminPROSITE-ProRule annotationAdd BLAST93
Repeati468 – 566FilaminPROSITE-ProRule annotationAdd BLAST99
Repeati569 – 661FilaminPROSITE-ProRule annotationAdd BLAST93
Repeati663 – 756FilaminPROSITE-ProRule annotationAdd BLAST94
Repeati760 – 852FilaminPROSITE-ProRule annotationAdd BLAST93
Repeati888 – 982FilaminPROSITE-ProRule annotationAdd BLAST95

Phylogenomic databases

eggNOGiKOG0518. Eukaryota.
COG5069. LUCA.
HOVERGENiHBG074524.
KOiK04437.

Family and domain databases

Gene3Di2.60.40.10. 10 hits.
InterProiView protein in InterPro
IPR017868. Filamin/ABP280_repeat-like.
IPR001298. Filamin/ABP280_rpt.
IPR028559. FLN_A.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
PANTHERiPTHR11915:SF348. PTHR11915:SF348. 1 hit.
PfamiView protein in Pfam
PF00630. Filamin. 9 hits.
SMARTiView protein in SMART
SM00557. IG_FLMN. 10 hits.
SUPFAMiSSF81296. SSF81296. 10 hits.
PROSITEiView protein in PROSITE
PS50194. FILAMIN_REPEAT. 10 hits.

Sequencei

Sequence statusi: Fragment.

Q6NXF2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
QIGEETVITV DTKAAGKGKV TCTVCTPDGS EVDVDVVENE DGTFDIFYTA
60 70 80 90 100
PQPGKYVICV RFGGEHVPNS PFQVTALAGD QPSVQPPLRS QQLAPQYTYA
110 120 130 140 150
QGGQQTWAPE RPLVGVNGLD VTSLRPFDLV IPFTIKKGEI TGEVRMPSGK
160 170 180 190 200
VAQPTITDNK DGTVTVRYAP SEAGLHEMDI RYDNMHIPGS PLQFYVDYVN
210 220 230 240 250
CGHVTAYGPG LTHGVVNKPA TFTVNTKDAG EGGLSLAIEG PSKAEISCTD
260 270 280 290 300
NQDGTCSVSY LPVLPGDYSI LVKYNEQHVP GSPFTARVTG DDSMRMSHLK
310 320 330 340 350
VGSAADIPIN ISETDLSLLT ATVVPPSGRE EPCLLKRLRN GHVGISFVPK
360 370 380 390 400
ETGEHLVHVK KNGQHVASSP IPVVISQSEI GDASRVRVSG QGLHEGHTFE
410 420 430 440 450
PAEFIIDTRD AGYGGLSLSI EGPSKVDINT EDLEDGTCRV TYCPTEPGNY
460 470 480 490 500
IINIKFADQH VPGSPFSVKV TGEGRVKESI TRRRRAPSVA NVGSHCDLSL
510 520 530 540 550
KIPEISIQDM TAQVTSPSGK THEAEIVEGE NHTYCIRFVP AEMGTHTVSV
560 570 580 590 600
KYKGQHVPGS PFQFTVGPLG EGGAHKVRAG GPGLERAEAG VPAEFSIWTR
610 620 630 640 650
EAGAGGLAIA VEGPSKAEIS FEDRKDGSCG VAYVVQEPGD YEVSVKFNEE
660 670 680 690 700
HIPDSPFVVP VASPSGDARR LTVSSLQESG LKVNQPASFA VSLNGAKGAI
710 720 730 740 750
DAKVHSPSGA LEECYVTEID QDKYAVRFIP RENGVYLIDV KFNGTHIPGS
760 770 780 790 800
PFKIRVGEPG HGGDPGLVSA YGAGLEGGVT GNPAEFVVNT SNAGAGALSV
810 820 830 840 850
TIDGPSKVKM DCQECPEGYR VTYTPMAPGS YLISIKYGGP YHIGGSPFKA
860 870 880 890 900
KVTGPRLVSN HSLHETSSVF VDSLTKATCA PQHGAPGPGP ADASKVVAKG
910 920 930 940 950
LGLSKAYVGQ KSSFTVDCSK AGNNMLLVGV HGPRTPCEEI LVKHVGSRLY
960 970 980
SVSYLLKDKG EYTLVVKWGD EHIPGSPYRV VVP
Length:983
Mass (Da):104,164
Last modified:July 5, 2004 - v1
Checksum:i8B944332B1AC27F3
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC067111 mRNA. Translation: AAH67111.1.
RefSeqiNP_001104026.1. NM_001110556.1.
NP_001447.2. NM_001456.3.
UniGeneiHs.195464.

Genome annotation databases

GeneIDi2316.
KEGGihsa:2316.

Similar proteinsi

Entry informationi

Entry nameiQ6NXF2_HUMAN
AccessioniPrimary (citable) accession number: Q6NXF2
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: August 30, 2017
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.