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Q6NXD4

- Q6NXD4_DANRE

UniProt

Q6NXD4 - Q6NXD4_DANRE

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Protein
Asparagine synthetase
Gene
asns
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + L-aspartate + L-glutamine + H2O = AMP + diphosphate + L-asparagine + L-glutamate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. asparagine synthase (glutamine-hydrolyzing) activity Source: UniProtKB-EC
Complete GO annotation...

GO - Biological processi

  1. L-asparagine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotation

Keywords - Biological processi

Amino-acid biosynthesis, Asparagine biosynthesisUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00134; UER00195.

Names & Taxonomyi

Protein namesi
Recommended name:
Asparagine synthetaseUniRule annotation (EC:6.3.5.4UniRule annotation)
Gene namesi
Name:asnsImported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Organism-specific databases

ZFINiZDB-GENE-040426-1091. asns.

PTM / Processingi

Proteomic databases

PRIDEiQ6NXD4.

Expressioni

Gene expression databases

BgeeiQ6NXD4.

Structurei

3D structure databases

ProteinModelPortaliQ6NXD4.

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG003103.
InParanoidiQ6NXD4.
KOiK01953.

Family and domain databases

Gene3Di3.40.50.620. 1 hit.
3.60.20.10. 1 hit.
InterProiIPR006426. Asn_synth_AEB.
IPR001962. Asn_synthase.
IPR017932. GATase_2_dom.
IPR000583. GATase_dom.
IPR029055. Ntn_hydrolases_N.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PfamiPF00733. Asn_synthase. 1 hit.
PF13537. GATase_7. 1 hit.
[Graphical view]
PIRSFiPIRSF001589. Asn_synthetase_glu-h. 1 hit.
SUPFAMiSSF56235. SSF56235. 1 hit.
TIGRFAMsiTIGR01536. asn_synth_AEB. 1 hit.
PROSITEiPS51278. GATASE_TYPE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6NXD4-1 [UniParc]FASTAAdd to Basket

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MCGIWALFGS DECLSVQCTN AMKIFHRGPD AFRFENVNGF TNCCFGFHRL    50
AIVDQLYGMQ PLRVKKFPYL WLCYNGEIYN HIKLKNHFEF DYQTKVDGEI 100
LLHLYDRFGI EKMCSLLDGV FAFILLDTAN RKVNLGRDTY GVRPLFRMLT 150
DDGFLAVCSE GKGLTQIKHS MPTAKITAFP PGHFEVFDLK LNGKVESVQM 200
DRFHCCTDKP KHADFNKLEG LGTDFELETV KSNIRILFED AVRKRLMAHR 250
RIGCLLSGGL DSSLVAALLV KLAKEEKLPY PIQTFSIGAE DSPDVAAARK 300
VADYIGSEHH VVNFTPEEGI SALEDVIVHL ESYDITTVRA SVGMYLVSKY 350
IREKTDSVVI FSGEGSDELT QGYIYFHKAP SPKAGAEDSV RLLEELYLFD 400
VLRADRTTAA HGLELRVPFL DHRFTAYYLS LPEEMRVPKN GVEKHLLRDA 450
FDGMNLIPDE ILWRRKEAFS DGLTSVKKSW YTSLQEHIES ELNDSQLENA 500
NKLYHINPPT TKEGLFIRQI FEKHYPGQGE WTPHYWMPRW IKATDPSART 550
LSIYKPDKEQ 560
Length:560
Mass (Da):63,997
Last modified:July 5, 2004 - v1
Checksum:i3B7A1C0A3326F5BA
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC067140 mRNA. Translation: AAH67140.1.
RefSeqiNP_957457.2. NM_201163.2.
UniGeneiDr.25168.

Genome annotation databases

GeneIDi394138.
KEGGidre:394138.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC067140 mRNA. Translation: AAH67140.1 .
RefSeqi NP_957457.2. NM_201163.2.
UniGenei Dr.25168.

3D structure databases

ProteinModelPortali Q6NXD4.
ModBasei Search...

Proteomic databases

PRIDEi Q6NXD4.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 394138.
KEGGi dre:394138.

Organism-specific databases

CTDi 440.
ZFINi ZDB-GENE-040426-1091. asns.

Phylogenomic databases

HOVERGENi HBG003103.
InParanoidi Q6NXD4.
KOi K01953.

Enzyme and pathway databases

UniPathwayi UPA00134 ; UER00195 .

Miscellaneous databases

NextBioi 20815089.

Gene expression databases

Bgeei Q6NXD4.

Family and domain databases

Gene3Di 3.40.50.620. 1 hit.
3.60.20.10. 1 hit.
InterProi IPR006426. Asn_synth_AEB.
IPR001962. Asn_synthase.
IPR017932. GATase_2_dom.
IPR000583. GATase_dom.
IPR029055. Ntn_hydrolases_N.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view ]
Pfami PF00733. Asn_synthase. 1 hit.
PF13537. GATase_7. 1 hit.
[Graphical view ]
PIRSFi PIRSF001589. Asn_synthetase_glu-h. 1 hit.
SUPFAMi SSF56235. SSF56235. 1 hit.
TIGRFAMsi TIGR01536. asn_synth_AEB. 1 hit.
PROSITEi PS51278. GATASE_TYPE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. NIH - Zebrafish Gene Collection (ZGC) project
    Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: KidneyImported.

Entry informationi

Entry nameiQ6NXD4_DANRE
AccessioniPrimary (citable) accession number: Q6NXD4
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: June 11, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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