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Q6NXD4

- Q6NXD4_DANRE

UniProt

Q6NXD4 - Q6NXD4_DANRE

Protein

Asparagine synthetase

Gene

asns

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 62 (01 Oct 2014)
      Sequence version 1 (05 Jul 2004)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + L-aspartate + L-glutamine + H2O = AMP + diphosphate + L-asparagine + L-glutamate.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. asparagine synthase (glutamine-hydrolyzing) activity Source: UniProtKB-EC
    2. ATP binding Source: UniProtKB-KW

    GO - Biological processi

    1. L-asparagine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    LigaseUniRule annotation

    Keywords - Biological processi

    Amino-acid biosynthesis, Asparagine biosynthesisUniRule annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotation, Nucleotide-binding

    Enzyme and pathway databases

    UniPathwayiUPA00134; UER00195.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Asparagine synthetaseUniRule annotation (EC:6.3.5.4UniRule annotation)
    Gene namesi
    Name:asnsImported
    OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
    Taxonomic identifieri7955 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

    Organism-specific databases

    ZFINiZDB-GENE-040426-1091. asns.

    PTM / Processingi

    Proteomic databases

    PRIDEiQ6NXD4.

    Expressioni

    Gene expression databases

    BgeeiQ6NXD4.

    Structurei

    3D structure databases

    ProteinModelPortaliQ6NXD4.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    HOVERGENiHBG003103.
    InParanoidiQ6NXD4.
    KOiK01953.

    Family and domain databases

    Gene3Di3.40.50.620. 1 hit.
    3.60.20.10. 1 hit.
    InterProiIPR006426. Asn_synth_AEB.
    IPR001962. Asn_synthase.
    IPR017932. GATase_2_dom.
    IPR000583. GATase_dom.
    IPR029055. Ntn_hydrolases_N.
    IPR014729. Rossmann-like_a/b/a_fold.
    [Graphical view]
    PfamiPF00733. Asn_synthase. 1 hit.
    PF13537. GATase_7. 1 hit.
    [Graphical view]
    PIRSFiPIRSF001589. Asn_synthetase_glu-h. 1 hit.
    SUPFAMiSSF56235. SSF56235. 1 hit.
    TIGRFAMsiTIGR01536. asn_synth_AEB. 1 hit.
    PROSITEiPS51278. GATASE_TYPE_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q6NXD4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MCGIWALFGS DECLSVQCTN AMKIFHRGPD AFRFENVNGF TNCCFGFHRL    50
    AIVDQLYGMQ PLRVKKFPYL WLCYNGEIYN HIKLKNHFEF DYQTKVDGEI 100
    LLHLYDRFGI EKMCSLLDGV FAFILLDTAN RKVNLGRDTY GVRPLFRMLT 150
    DDGFLAVCSE GKGLTQIKHS MPTAKITAFP PGHFEVFDLK LNGKVESVQM 200
    DRFHCCTDKP KHADFNKLEG LGTDFELETV KSNIRILFED AVRKRLMAHR 250
    RIGCLLSGGL DSSLVAALLV KLAKEEKLPY PIQTFSIGAE DSPDVAAARK 300
    VADYIGSEHH VVNFTPEEGI SALEDVIVHL ESYDITTVRA SVGMYLVSKY 350
    IREKTDSVVI FSGEGSDELT QGYIYFHKAP SPKAGAEDSV RLLEELYLFD 400
    VLRADRTTAA HGLELRVPFL DHRFTAYYLS LPEEMRVPKN GVEKHLLRDA 450
    FDGMNLIPDE ILWRRKEAFS DGLTSVKKSW YTSLQEHIES ELNDSQLENA 500
    NKLYHINPPT TKEGLFIRQI FEKHYPGQGE WTPHYWMPRW IKATDPSART 550
    LSIYKPDKEQ 560
    Length:560
    Mass (Da):63,997
    Last modified:July 5, 2004 - v1
    Checksum:i3B7A1C0A3326F5BA
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC067140 mRNA. Translation: AAH67140.1.
    RefSeqiNP_957457.2. NM_201163.2.
    UniGeneiDr.25168.

    Genome annotation databases

    GeneIDi394138.
    KEGGidre:394138.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC067140 mRNA. Translation: AAH67140.1 .
    RefSeqi NP_957457.2. NM_201163.2.
    UniGenei Dr.25168.

    3D structure databases

    ProteinModelPortali Q6NXD4.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q6NXD4.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 394138.
    KEGGi dre:394138.

    Organism-specific databases

    CTDi 440.
    ZFINi ZDB-GENE-040426-1091. asns.

    Phylogenomic databases

    HOVERGENi HBG003103.
    InParanoidi Q6NXD4.
    KOi K01953.

    Enzyme and pathway databases

    UniPathwayi UPA00134 ; UER00195 .

    Miscellaneous databases

    NextBioi 20815089.

    Gene expression databases

    Bgeei Q6NXD4.

    Family and domain databases

    Gene3Di 3.40.50.620. 1 hit.
    3.60.20.10. 1 hit.
    InterProi IPR006426. Asn_synth_AEB.
    IPR001962. Asn_synthase.
    IPR017932. GATase_2_dom.
    IPR000583. GATase_dom.
    IPR029055. Ntn_hydrolases_N.
    IPR014729. Rossmann-like_a/b/a_fold.
    [Graphical view ]
    Pfami PF00733. Asn_synthase. 1 hit.
    PF13537. GATase_7. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF001589. Asn_synthetase_glu-h. 1 hit.
    SUPFAMi SSF56235. SSF56235. 1 hit.
    TIGRFAMsi TIGR01536. asn_synth_AEB. 1 hit.
    PROSITEi PS51278. GATASE_TYPE_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. NIH - Zebrafish Gene Collection (ZGC) project
      Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: KidneyImported.

    Entry informationi

    Entry nameiQ6NXD4_DANRE
    AccessioniPrimary (citable) accession number: Q6NXD4
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 5, 2004
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 62 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)