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Q6NXD1

- Q6NXD1_DANRE

UniProt

Q6NXD1 - Q6NXD1_DANRE

Protein

Pyruvate kinase

Gene

pkma

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 68 (01 Oct 2014)
      Sequence version 1 (05 Jul 2004)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + pyruvate = ADP + phosphoenolpyruvate.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. magnesium ion binding Source: InterPro
    2. potassium ion binding Source: InterPro
    3. pyruvate kinase activity Source: UniProtKB-EC

    GO - Biological processi

    1. glycolytic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    KinaseUniRule annotation, Transferase

    Keywords - Biological processi

    GlycolysisUniRule annotation

    Keywords - Ligandi

    MagnesiumUniRule annotation

    Enzyme and pathway databases

    UniPathwayiUPA00109; UER00188.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Pyruvate kinaseUniRule annotation (EC:2.7.1.40UniRule annotation)
    Gene namesi
    Name:pkmaImported
    Synonyms:pkm2aImported
    OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
    Taxonomic identifieri7955 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

    Organism-specific databases

    ZFINiZDB-GENE-031201-4. pkma.

    PTM / Processingi

    Proteomic databases

    PRIDEiQ6NXD1.

    Expressioni

    Gene expression databases

    BgeeiQ6NXD1.

    Structurei

    3D structure databases

    ProteinModelPortaliQ6NXD1.
    SMRiQ6NXD1. Positions 14-532.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the pyruvate kinase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0469.
    HOGENOMiHOG000021559.
    HOVERGENiHBG000941.

    Family and domain databases

    Gene3Di2.40.33.10. 1 hit.
    3.20.20.60. 2 hits.
    3.40.1380.20. 1 hit.
    InterProiIPR001697. Pyr_Knase.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    IPR011037. Pyrv_Knase-like_insert_dom.
    IPR015794. Pyrv_Knase_a/b.
    IPR018209. Pyrv_Knase_AS.
    IPR015793. Pyrv_Knase_brl.
    IPR015795. Pyrv_Knase_C.
    IPR015806. Pyrv_Knase_insert_dom.
    [Graphical view]
    PANTHERiPTHR11817. PTHR11817. 1 hit.
    PfamiPF00224. PK. 1 hit.
    PF02887. PK_C. 1 hit.
    [Graphical view]
    PRINTSiPR01050. PYRUVTKNASE.
    SUPFAMiSSF50800. SSF50800. 1 hit.
    SSF51621. SSF51621. 2 hits.
    SSF52935. SSF52935. 1 hit.
    TIGRFAMsiTIGR01064. pyruv_kin. 1 hit.
    PROSITEiPS00110. PYRUVATE_KINASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q6NXD1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSQTKAQDMG SAFIQTQQLN AAMADTFLEH MCLLDIDSEP TIARNTGIIC    50
    TIGPASRSVD TLKEMIKSGM NIARMNFSHG SHEYHGETIK NVREACASFK 100
    PGSIQYRPVG IALDTKGPEI RTGLIKGSGT AEVELKKGNK IKVTLDDSFM 150
    ENCDEDTLWL DYKNITKVVE VGSKVYIDDG LISLQVLQIG SDYLICEIEN 200
    GGSLGSKKGV NLPGAAVDLP AVSEKDIKDL QFGVEMGVDM IFASFIRKAA 250
    DVQAVRKVLG EKGKNIKIIS KLENHEGVRR FDEIMEASDG IMVARGDLGI 300
    EIPTEKVFLA QKMMIGRCNK AGKPIICATQ MLESMIKKPR PTRAEGSDVA 350
    NAVLDGADCI MLSGETAKGD YPLEAVRTQH MIAREAEAAM FHRQVFEDLR 400
    RCLPLSTDPA EAIAIGAVEA SFKILSSAFI VLTGSGRSAH LISRYRPRAP 450
    ILAVTRNEQT ARQAHLYRGI FPIYYNSPSN DVWAEDVDLR VNFAMDVGKA 500
    RGFFKAGDVV IVLTGWRPGS GYTNTMRVVP VP 532
    Length:532
    Mass (Da):58,113
    Last modified:July 5, 2004 - v1
    Checksum:iE598BCC73721D43D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC067143 mRNA. Translation: AAH67143.1.
    UniGeneiDr.79861.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC067143 mRNA. Translation: AAH67143.1 .
    UniGenei Dr.79861.

    3D structure databases

    ProteinModelPortali Q6NXD1.
    SMRi Q6NXD1. Positions 14-532.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q6NXD1.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    ZFINi ZDB-GENE-031201-4. pkma.

    Phylogenomic databases

    eggNOGi COG0469.
    HOGENOMi HOG000021559.
    HOVERGENi HBG000941.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00188 .

    Gene expression databases

    Bgeei Q6NXD1.

    Family and domain databases

    Gene3Di 2.40.33.10. 1 hit.
    3.20.20.60. 2 hits.
    3.40.1380.20. 1 hit.
    InterProi IPR001697. Pyr_Knase.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    IPR011037. Pyrv_Knase-like_insert_dom.
    IPR015794. Pyrv_Knase_a/b.
    IPR018209. Pyrv_Knase_AS.
    IPR015793. Pyrv_Knase_brl.
    IPR015795. Pyrv_Knase_C.
    IPR015806. Pyrv_Knase_insert_dom.
    [Graphical view ]
    PANTHERi PTHR11817. PTHR11817. 1 hit.
    Pfami PF00224. PK. 1 hit.
    PF02887. PK_C. 1 hit.
    [Graphical view ]
    PRINTSi PR01050. PYRUVTKNASE.
    SUPFAMi SSF50800. SSF50800. 1 hit.
    SSF51621. SSF51621. 2 hits.
    SSF52935. SSF52935. 1 hit.
    TIGRFAMsi TIGR01064. pyruv_kin. 1 hit.
    PROSITEi PS00110. PYRUVATE_KINASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. NIH - Zebrafish Gene Collection (ZGC) project
      Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: KidneyImported.

    Entry informationi

    Entry nameiQ6NXD1_DANRE
    AccessioniPrimary (citable) accession number: Q6NXD1
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 5, 2004
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 68 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)