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Q6NXD1 (Q6NXD1_DANRE) Unreviewed, UniProtKB/TrEMBL

Last modified March 6, 2013. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length532 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

ATP + pyruvate = ADP + phosphoenolpyruvate. RuleBase RU000504

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 5/5. RuleBase RU000504

Sequence similarities

Belongs to the pyruvate kinase family. RuleBase RU000504

Ontologies

Keywords
   Biological processGlycolysis RuleBase RU000504
   LigandMagnesium RuleBase RU000504
   Molecular functionKinase RuleBase RU000504
Transferase
Gene Ontology (GO)
   Biological_processglycolysis

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Molecular_functionmagnesium ion binding

Inferred from electronic annotation. Source: InterPro

potassium ion binding

Inferred from electronic annotation. Source: InterPro

pyruvate kinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
Q6NXD1 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: E598BCC73721D43D

FASTA53258,113
        10         20         30         40         50         60 
MSQTKAQDMG SAFIQTQQLN AAMADTFLEH MCLLDIDSEP TIARNTGIIC TIGPASRSVD 

        70         80         90        100        110        120 
TLKEMIKSGM NIARMNFSHG SHEYHGETIK NVREACASFK PGSIQYRPVG IALDTKGPEI 

       130        140        150        160        170        180 
RTGLIKGSGT AEVELKKGNK IKVTLDDSFM ENCDEDTLWL DYKNITKVVE VGSKVYIDDG 

       190        200        210        220        230        240 
LISLQVLQIG SDYLICEIEN GGSLGSKKGV NLPGAAVDLP AVSEKDIKDL QFGVEMGVDM 

       250        260        270        280        290        300 
IFASFIRKAA DVQAVRKVLG EKGKNIKIIS KLENHEGVRR FDEIMEASDG IMVARGDLGI 

       310        320        330        340        350        360 
EIPTEKVFLA QKMMIGRCNK AGKPIICATQ MLESMIKKPR PTRAEGSDVA NAVLDGADCI 

       370        380        390        400        410        420 
MLSGETAKGD YPLEAVRTQH MIAREAEAAM FHRQVFEDLR RCLPLSTDPA EAIAIGAVEA 

       430        440        450        460        470        480 
SFKILSSAFI VLTGSGRSAH LISRYRPRAP ILAVTRNEQT ARQAHLYRGI FPIYYNSPSN 

       490        500        510        520        530 
DVWAEDVDLR VNFAMDVGKA RGFFKAGDVV IVLTGWRPGS GYTNTMRVVP VP

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References

[1]NIH - Zebrafish Gene Collection (ZGC) project
Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Kidney EMBL AAH67143.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BC067143 mRNA. Translation: AAH67143.1.
IPIIPI00499318.
UniGeneDr.79861.

3D structure databases

HSSPHSSP built from PDB template 1AQF based on UniProtKB P11974.
ProteinModelPortalQ6NXD1.
SMRQ6NXD1. Positions 14-532.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ6NXD1.

Proteomic databases

PRIDEQ6NXD1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

ZFINZDB-GENE-031201-4. pkma.

Phylogenomic databases

eggNOGCOG0469.
HOGENOMHOG000021559.
HOVERGENHBG000941.

Enzyme and pathway databases

UniPathwayUPA00109; UER00188.

Gene expression databases

ArrayExpressQ6NXD1.
BgeeQ6NXD1.

Family and domain databases

Gene3D2.40.33.10. 1 hit.
3.20.20.60. 2 hits.
3.40.1380.20. 1 hit.
InterProIPR001697. Pyr_Knase.
IPR015813. Pyrv/PenolPyrv_Kinase.
IPR011037. Pyrv_Knase-like_insert_dom.
IPR015794. Pyrv_Knase_a/b.
IPR018209. Pyrv_Knase_AS.
IPR015793. Pyrv_Knase_brl.
IPR015795. Pyrv_Knase_C.
IPR015806. Pyrv_Knase_insert_dom.
[Graphical view]
PANTHERPTHR11817. PTHR11817. 1 hit.
PfamPF00224. PK. 1 hit.
PF02887. PK_C. 1 hit.
[Graphical view]
PRINTSPR01050. PYRUVTKNASE.
SUPFAMSSF50800. PK_B_barrel_like. 1 hit.
SSF52935. Pyruvate_kinase. 1 hit.
SSF51621. Pyrv/PenolPyrv_Kinase_cat. 1 hit.
TIGRFAMsTIGR01064. pyruv_kin. 1 hit.
PROSITEPS00110. PYRUVATE_KINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ6NXD1_DANRE
AccessionPrimary (citable) accession number: Q6NXD1
Entry history
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: March 6, 2013
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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