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Protein
Submitted name:

Exocyst complex component 4

Gene

EXOC4

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Exocyst complex component 4Imported
Gene namesi
Name:EXOC4Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134944654.

PTM / Processingi

Proteomic databases

PaxDbiQ6NX51.
PeptideAtlasiQ6NX51.
PRIDEiQ6NX51.

PTM databases

iPTMnetiQ6NX51.

Expressioni

Gene expression databases

GenevisibleiQ6NX51. HS.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000253861.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini46 – 14398Sec8_exocystInterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili37 – 6428Sequence analysisAdd
BLAST

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG3691. Eukaryota.
ENOG410Z8N0. LUCA.
HOVERGENiHBG036151.

Family and domain databases

InterProiIPR007191. Sec8_exocyst.
[Graphical view]
PfamiPF04048. Sec8_exocyst. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6NX51-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAEAAGGKY RSTVSKSKDP SGLLISVIRT LSTSDDVEDR ENEKGRLEEA
60 70 80 90 100
YEKCDRDLDE LIVQHYTELT TAIRTYQSIT ERITNSRNKI KQVKENLLSC
110 120 130 140 150
KMLLHCKRDE LRKLWIEGIE HKHVLNLLDE IENIKQVPQK LEQCMASKHY
160 170 180 190 200
LSATDMLVSA VESLEGPLLQ VEGLSDLRLE LHSKKMNLHL VLIDELHRHL
210 220 230 240 250
YIKSTSRVVQ RNKEKGKISS LVKDASVPLI DVTNLPTPRK FLDTSHYSTA
260 270 280 290 300
GSSSVREINL QDIKEDLELD PEENSTLFMG ILIKGLAKLK KIPETVKAII
310 320 330 340 350
ERLEQELKQI VKRSTTQVAD SGYQRGENVT VENQPRLLLE LLELLFDKFN
360 370 380 390 400
AVAAAHSVVL GYLQDTVVTP LTQQEDIKLY DMADVWVKIQ DVLQMLLTEY
410 420 430 440 450
LDMKNTRTAS EPSAQLSYAS TGREFAAFFA KKKPQRPKNS LFKFESSSHA
460 470 480 490 500
ISMSAYLREQ RRELYSRSGE LQGGPDDNLL EGGGTKFVCK PGARNITVIF
510 520 530 540 550
HPLLRFIQEI EHALGLGPAK QCPLREFLTV YIKNIFLNQV LAEINKEIEG
560 570 580 590 600
VTKTSDPLKI LANADTMKVL GVQRPLLQST IIVEKTVQDL LNLMHDLSAY
610 620 630 640 650
SDQFLNMVCV KLQEYKDTCT AAYRGIVQSE EKLVISASWA KDDDISRLLK
660 670 680 690 700
SLPNWMNMAQ PKQLRPKREE EEDFIRAAFG KESEVLIGNL GDKLIPPQDI
710 720 730 740 750
LRDVSDLKAL ANMHESLEWL ASRTKSAFSN LSTSQMLSPA QDSHTNTDLP
760 770 780 790 800
PVSEQIMQTL SELAKSFQDM ADRCLLVLHL EVRVHCFHYL IPLAKEGNYA
810 820 830 840 850
IVANVESMDY DPLVVKLNKD ISAIEEAMSA SLQQHKFQYI FEGLGHLISC
860 870 880 890 900
ILINGAQYFR RISESGIKKM CRNIFVLQQN LTNITMSREA DLDFARQYYE
910 920 930 940 950
MLYNTADELL NLVVDQGVKY TELEYIHALT LLHRSQTGVG ELTTQNTRLQ
960 970
RLKEIICEQA AIKQATKDKK ITTV
Length:974
Mass (Da):110,498
Last modified:July 5, 2004 - v1
Checksum:i8F9A024474B83BDA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC067263 mRNA. Translation: AAH67263.1.
RefSeqiNP_001032203.1. NM_001037126.1.
UniGeneiHs.321273.

Genome annotation databases

GeneIDi60412.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC067263 mRNA. Translation: AAH67263.1.
RefSeqiNP_001032203.1. NM_001037126.1.
UniGeneiHs.321273.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000253861.

PTM databases

iPTMnetiQ6NX51.

Proteomic databases

PaxDbiQ6NX51.
PeptideAtlasiQ6NX51.
PRIDEiQ6NX51.

Protocols and materials databases

DNASUi60412.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi60412.

Organism-specific databases

CTDi60412.
PharmGKBiPA134944654.

Phylogenomic databases

eggNOGiKOG3691. Eukaryota.
ENOG410Z8N0. LUCA.
HOVERGENiHBG036151.

Miscellaneous databases

ChiTaRSiEXOC4. human.
GenomeRNAii60412.

Gene expression databases

GenevisibleiQ6NX51. HS.

Family and domain databases

InterProiIPR007191. Sec8_exocyst.
[Graphical view]
PfamiPF04048. Sec8_exocyst. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Peripheral Nervous SystemImported.

Entry informationi

Entry nameiQ6NX51_HUMAN
AccessioniPrimary (citable) accession number: Q6NX51
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: July 6, 2016
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.