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Q6NWP6

- Q6NWP6_HUMAN

UniProt

Q6NWP6 - Q6NWP6_HUMAN

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Protein
Submitted name: Interleukin 1 receptor, type I
Gene
IL1R1
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. interleukin-1, Type I, activating receptor activity Source: InterPro
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Keywords - Molecular functioni

    ReceptorImported

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Interleukin 1 receptor, type IImported
    Gene namesi
    Name:IL1R1Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    PTM / Processingi

    Proteomic databases

    PRIDEiQ6NWP6.

    Structurei

    3D structure databases

    ProteinModelPortaliQ6NWP6.
    SMRiQ6NWP6. Positions 21-331.

    Family & Domainsi

    Phylogenomic databases

    HOVERGENiHBG052103.

    Family and domain databases

    Gene3Di2.60.40.10. 3 hits.
    3.40.50.10140. 1 hit.
    InterProiIPR007110. Ig-like_dom.
    IPR013783. Ig-like_fold.
    IPR013098. Ig_I-set.
    IPR003599. Ig_sub.
    IPR015621. IL-1_rcpt_fam.
    IPR004076. IL-1_rcpt_I-typ.
    IPR004074. IL-1_rcpt_I/II-typ.
    IPR000157. TIR_dom.
    [Graphical view]
    PANTHERiPTHR11890. PTHR11890. 1 hit.
    PfamiPF07679. I-set. 1 hit.
    PF01582. TIR. 1 hit.
    [Graphical view]
    PRINTSiPR01538. INTRLEUKN1R1.
    PR01536. INTRLKN1R12F.
    SMARTiSM00409. IG. 2 hits.
    SM00255. TIR. 1 hit.
    [Graphical view]
    SUPFAMiSSF52200. SSF52200. 1 hit.
    PROSITEiPS50835. IG_LIKE. 2 hits.
    PS50104. TIR. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q6NWP6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKVLLRLICF IALLISSLEA DKCKEREEKI ILVSSANEID VRPCPLNPNE    50
    HKGTITWYKD DSKTPVSTEQ ASRIHQHKEK LWFVPAKVED SGHYYCVVRN 100
    SSYCLRIKIS AKFVENEPNL CYNAQAIFKQ KLPVAGDGGL VCPYMEFFKN 150
    ENNELPKLQW YKDCKPLLLD NIHFSGVKDR LIVMNVAEKH RGNYTRHASY 200
    TYLGKQYPIT RVIEFITLEE NKPTRPVIVS PANETMEVDL GSQIQLICNV 250
    TGQLSDIAYW KWNGSVIDED DPVLGEDYYS VENPANKRRS TLITVLNISE 300
    IESRFYKHPF TCFAKNTHGI DAAYIQLIYP VTNFQKHMIG ICVTLTVIIV 350
    CSVFIYKIFK IDIVLWYRDS CYDFLPIKAS DGKTYDAYIL YPKTVGEGST 400
    SDCDIFVFKV LPGVLEKQCG YKLFIYGRDD YVGEDIVEVI NENVKKSRRL 450
    IIILVRETSG FSWLGGSSEE QIAMYNALVQ DGIKVVLLEL EKIQDYEKMP 500
    ESIKFIKQKH GTIRWSGDFT QGPQSAKTRF WKNVRYHMPV QRRSPSSKHQ 550
    LLSPATKEKL QREAHVPLG 569
    Length:569
    Mass (Da):65,413
    Last modified:July 5, 2004 - v1
    Checksum:iCEDB80A174225AB2
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC067507 mRNA. Translation: AAH67507.1.
    UniGeneiHs.701982.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC067507 mRNA. Translation: AAH67507.1 .
    UniGenei Hs.701982.

    3D structure databases

    ProteinModelPortali Q6NWP6.
    SMRi Q6NWP6. Positions 21-331.
    ModBasei Search...

    Proteomic databases

    PRIDEi Q6NWP6.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    HOVERGENi HBG052103.

    Miscellaneous databases

    ChiTaRSi IL1R1. human.

    Family and domain databases

    Gene3Di 2.60.40.10. 3 hits.
    3.40.50.10140. 1 hit.
    InterProi IPR007110. Ig-like_dom.
    IPR013783. Ig-like_fold.
    IPR013098. Ig_I-set.
    IPR003599. Ig_sub.
    IPR015621. IL-1_rcpt_fam.
    IPR004076. IL-1_rcpt_I-typ.
    IPR004074. IL-1_rcpt_I/II-typ.
    IPR000157. TIR_dom.
    [Graphical view ]
    PANTHERi PTHR11890. PTHR11890. 1 hit.
    Pfami PF07679. I-set. 1 hit.
    PF01582. TIR. 1 hit.
    [Graphical view ]
    PRINTSi PR01538. INTRLEUKN1R1.
    PR01536. INTRLKN1R12F.
    SMARTi SM00409. IG. 2 hits.
    SM00255. TIR. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52200. SSF52200. 1 hit.
    PROSITEi PS50835. IG_LIKE. 2 hits.
    PS50104. TIR. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
      , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].

    Entry informationi

    Entry nameiQ6NWP6_HUMAN
    AccessioniPrimary (citable) accession number: Q6NWP6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 5, 2004
    Last sequence update: July 5, 2004
    Last modified: April 16, 2014
    This is version 86 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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