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Protein
Submitted name:

Chaperonin containing TCP1, subunit 5 (Epsilon)

Gene

cct5

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Molecular chaperone; assists the folding of proteins upon ATP hydrolysis.SAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperoneUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-DRE-390471. Association of TriC/CCT with target proteins during biosynthesis.
R-DRE-6814122. Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding.

Names & Taxonomyi

Protein namesi
Submitted name:
Chaperonin containing TCP1, subunit 5 (Epsilon)Imported
Submitted name:
Chaperonin-containing TCP1, subunit 5 (epsilon)Imported
Submitted name:
TCP-1 epsilonImported
Gene namesi
Name:cct5Imported
Synonyms:CCT5Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 24

Organism-specific databases

ZFINiZDB-GENE-030131-977. cct5.

Subcellular locationi

  • Cytoplasm SAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmSAAS annotation

Expressioni

Gene expression databases

BgeeiENSDARG00000045399.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000066759.

Family & Domainsi

Sequence similaritiesi

Belongs to the TCP-1 chaperonin family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0357. Eukaryota.
COG0459. LUCA.
GeneTreeiENSGT00550000074988.
HOGENOMiHOG000226735.
HOVERGENiHBG106507.
KOiK09497.
OMAiLKVNNVI.
OrthoDBiEOG091G05G4.
TreeFamiTF105638.

Family and domain databases

CDDicd03339. TCP1_epsilon. 1 hit.
Gene3Di1.10.560.10. 2 hits.
3.50.7.10. 1 hit.
InterProiView protein in InterPro
IPR012718. Chap_CCT_epsi.
IPR017998. Chaperone_TCP-1.
IPR002194. Chaperonin_TCP-1_CS.
IPR002423. Cpn60/TCP-1.
IPR027409. GroEL-like_apical_dom.
IPR027413. GROEL-like_equatorial.
PANTHERiPTHR11353:SF156. PTHR11353:SF156. 1 hit.
PfamiView protein in Pfam
PF00118. Cpn60_TCP1. 1 hit.
PRINTSiPR00304. TCOMPLEXTCP1.
SUPFAMiSSF52029. SSF52029. 1 hit.
TIGRFAMsiTIGR02343. chap_CCT_epsi. 1 hit.
PROSITEiView protein in PROSITE
PS00750. TCP1_1. 1 hit.
PS00751. TCP1_2. 1 hit.
PS00995. TCP1_3. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6NVI6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSALGTLAFD EYGRPFIIIK DQDKKSRLTG LEALKSHILA AKAVANTLRT
60 70 80 90 100
SLGPNGLDKM MVDKDGEVTV TNDGATILSM MDVDHQIAKL MVELSKSQDD
110 120 130 140 150
EIGDGTTGVV VLAGALLEQA EQLLDRGIHP IRIADGYDQA AKIAIEQLDK
160 170 180 190 200
IGDSFPVDPN NTESLVQTAM TTLGSKVINR CHRQMAEIAV NAILTVADME
210 220 230 240 250
RKDVDFELIK VEGKVGGKLE DTQLIKGVIV DKEFSHPQMP KVLKDTKIAI
260 270 280 290 300
LTCPFEPPKP KTKHKLDVTS VEDYKALQKY EKDKFQEMIR QVKENGANLA
310 320 330 340 350
ICQWGFDDEA NHLLLQNELP AIRWVGGPEI ELIAIATGGR IVPRFCELTP
360 370 380 390 400
EKLGTAGLVK EICFGTTKDR MLVIEECKNS RAVTIFIRGG NKMIIEEAKR
410 420 430 440 450
ALHDALCVIR NLVRDNRIVY GGGASEIACA LAVNEAADKC PSLEQYAMRA
460 470 480 490 500
FADALEVIPM ALAENSGLNP IQTMTEVRAR QVKENNSALG IDCLHLSTND
510 520 530 540
MKQQHVIETL IGKKQQISLA TQVVKMILKI DDIRGPGEPE D
Length:541
Mass (Da):59,395
Last modified:July 5, 2004 - v1
Checksum:iCB122625F602B4B4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX469922 Genomic DNA. No translation available.
BC068037 mRNA. Translation: AAH68037.1.
AY398321 mRNA. Translation: AAQ97754.1.
AY648807 mRNA. Translation: AAT68125.1.
RefSeqiNP_997778.1. NM_212613.1.
UniGeneiDr.75968.

Genome annotation databases

EnsembliENSDART00000066760; ENSDARP00000066759; ENSDARG00000045399.
GeneIDi322258.
KEGGidre:322258.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX469922 Genomic DNA. No translation available.
BC068037 mRNA. Translation: AAH68037.1.
AY398321 mRNA. Translation: AAQ97754.1.
AY648807 mRNA. Translation: AAT68125.1.
RefSeqiNP_997778.1. NM_212613.1.
UniGeneiDr.75968.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000066759.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000066760; ENSDARP00000066759; ENSDARG00000045399.
GeneIDi322258.
KEGGidre:322258.

Organism-specific databases

CTDi22948.
ZFINiZDB-GENE-030131-977. cct5.

Phylogenomic databases

eggNOGiKOG0357. Eukaryota.
COG0459. LUCA.
GeneTreeiENSGT00550000074988.
HOGENOMiHOG000226735.
HOVERGENiHBG106507.
KOiK09497.
OMAiLKVNNVI.
OrthoDBiEOG091G05G4.
TreeFamiTF105638.

Enzyme and pathway databases

ReactomeiR-DRE-390471. Association of TriC/CCT with target proteins during biosynthesis.
R-DRE-6814122. Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding.

Gene expression databases

BgeeiENSDARG00000045399.

Family and domain databases

CDDicd03339. TCP1_epsilon. 1 hit.
Gene3Di1.10.560.10. 2 hits.
3.50.7.10. 1 hit.
InterProiView protein in InterPro
IPR012718. Chap_CCT_epsi.
IPR017998. Chaperone_TCP-1.
IPR002194. Chaperonin_TCP-1_CS.
IPR002423. Cpn60/TCP-1.
IPR027409. GroEL-like_apical_dom.
IPR027413. GROEL-like_equatorial.
PANTHERiPTHR11353:SF156. PTHR11353:SF156. 1 hit.
PfamiView protein in Pfam
PF00118. Cpn60_TCP1. 1 hit.
PRINTSiPR00304. TCOMPLEXTCP1.
SUPFAMiSSF52029. SSF52029. 1 hit.
TIGRFAMsiTIGR02343. chap_CCT_epsi. 1 hit.
PROSITEiView protein in PROSITE
PS00750. TCP1_1. 1 hit.
PS00751. TCP1_2. 1 hit.
PS00995. TCP1_3. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ6NVI6_DANRE
AccessioniPrimary (citable) accession number: Q6NVI6
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: June 7, 2017
This is version 123 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.