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Protein
Submitted name:

SLC25A5 protein

Gene

SLC25A5

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

TransportUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
SLC25A5 proteinImported
Gene namesi
Name:SLC25A5Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei236 – 25621HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA35867.

PTM / Processingi

Proteomic databases

PaxDbiQ6NVC0.
PRIDEiQ6NVC0.

Expressioni

Gene expression databases

BgeeiQ6NVC0.
GenevisibleiQ6NVC0. HS.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000360671.

Structurei

3D structure databases

ProteinModelPortaliQ6NVC0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the mitochondrial carrier (TC 2.A.29) family. [View classification]UniRule annotationSAAS annotation

Keywords - Domaini

RepeatSAAS annotation, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG0749. Eukaryota.
ENOG410XNW0. LUCA.
HOGENOMiHOG000165727.
HOVERGENiHBG108348.
KOiK05863.

Family and domain databases

Gene3Di1.50.40.10. 1 hit.
InterProiIPR002113. Aden_trnslctor.
IPR002067. Mit_carrier.
IPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom.
[Graphical view]
PfamiPF00153. Mito_carr. 3 hits.
[Graphical view]
PRINTSiPR00927. ADPTRNSLCASE.
PR00926. MITOCARRIER.
SUPFAMiSSF103506. SSF103506. 1 hit.
PROSITEiPS50920. SOLCAR. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q6NVC0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
GARSAGVKAG SRPSPVLQQS ASSFNMTDAA VSFAKDFLAG GVAAAISKTA
60 70 80 90 100
VAPIERVKLL LQVQHASKQI TADKQYKGII DCVVRIPKEQ GVLSFWRGNL
110 120 130 140 150
ANVIRYFPTQ ALNFAFKDKY KQIFLGGVDK RTQFWLYFAG NLASGGAAGA
160 170 180 190 200
TSLCFVYPLD FARTRLAADV GKAGAEREFR GLGDCLVKIY KSDGIKGLYQ
210 220 230 240 250
GFNVSVQGII IYRAAYFGIY DTAKGMLPDP KNTHIVISWM IAQTVTAVAG
260 270 280 290 300
LTSYPFDTVR RRMMMQSGRK GTDIMYTGTL DCWRKIARDE GGKAFFKGAW
310 320
SNVLRGMGGA FVLVLYDEIK KYT
Length:323
Mass (Da):35,294
Last modified:July 5, 2004 - v1
Checksum:i2169F1DD822DC5EC
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC068199 mRNA. Translation: AAH68199.1.
RefSeqiNP_001143.2. NM_001152.4.
UniGeneiHs.632282.

Genome annotation databases

GeneIDi292.
KEGGihsa:292.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC068199 mRNA. Translation: AAH68199.1.
RefSeqiNP_001143.2. NM_001152.4.
UniGeneiHs.632282.

3D structure databases

ProteinModelPortaliQ6NVC0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000360671.

Proteomic databases

PaxDbiQ6NVC0.
PRIDEiQ6NVC0.

Protocols and materials databases

DNASUi292.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi292.
KEGGihsa:292.

Organism-specific databases

CTDi292.
PharmGKBiPA35867.

Phylogenomic databases

eggNOGiKOG0749. Eukaryota.
ENOG410XNW0. LUCA.
HOGENOMiHOG000165727.
HOVERGENiHBG108348.
KOiK05863.

Miscellaneous databases

ChiTaRSiSLC25A5. human.
GenomeRNAii292.

Gene expression databases

BgeeiQ6NVC0.
GenevisibleiQ6NVC0. HS.

Family and domain databases

Gene3Di1.50.40.10. 1 hit.
InterProiIPR002113. Aden_trnslctor.
IPR002067. Mit_carrier.
IPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom.
[Graphical view]
PfamiPF00153. Mito_carr. 3 hits.
[Graphical view]
PRINTSiPR00927. ADPTRNSLCASE.
PR00926. MITOCARRIER.
SUPFAMiSSF103506. SSF103506. 1 hit.
PROSITEiPS50920. SOLCAR. 3 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Bone marrowImported.

Entry informationi

Entry nameiQ6NVC0_HUMAN
AccessioniPrimary (citable) accession number: Q6NVC0
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: June 8, 2016
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.