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Protein

Uncharacterized protein KIAA1211-like

Gene

KIAA1211L

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein KIAA1211-like
Gene namesi
Name:KIAA1211L
Synonyms:C2orf55
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

HGNCiHGNC:33454. KIAA1211L.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA31767.

Polymorphism and mutation databases

BioMutaiKIAA1211L.
DMDMi215274155.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 962962Uncharacterized protein KIAA1211-likePRO_0000289161Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei92 – 921PhosphoserineCombined sources
Modified residuei490 – 4901PhosphoserineCombined sources

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiQ6NV74.
MaxQBiQ6NV74.
PaxDbiQ6NV74.
PeptideAtlasiQ6NV74.
PRIDEiQ6NV74.

PTM databases

iPTMnetiQ6NV74.
PhosphoSiteiQ6NV74.

Expressioni

Gene expression databases

BgeeiQ6NV74.
CleanExiHS_C2orf55.
ExpressionAtlasiQ6NV74. baseline and differential.
GenevisibleiQ6NV74. HS.

Organism-specific databases

HPAiHPA051082.
HPA061678.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000380996.

Structurei

3D structure databases

ProteinModelPortaliQ6NV74.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi287 – 549263Pro-richAdd
BLAST
Compositional biasi752 – 82574Pro-richAdd
BLAST

Phylogenomic databases

eggNOGiENOG410IIB6. Eukaryota.
ENOG410YAR8. LUCA.
GeneTreeiENSGT00740000115532.
HOGENOMiHOG000111324.
InParanoidiQ6NV74.
OMAiCAPATDK.
OrthoDBiEOG7WX08B.
PhylomeDBiQ6NV74.
TreeFamiTF335584.

Family and domain databases

InterProiIPR028030. DUF4592.
IPR026713. KIAA1211L.
[Graphical view]
PANTHERiPTHR22118:SF16. PTHR22118:SF16. 2 hits.
PfamiPF15262. DUF4592. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6NV74-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MISTRVMDIK LREAAEGLGE DSTGKKKSKF KTFKKFFGKK KRKESPSSTG
60 70 80 90 100
SSTWKQSQTR NEVIAIESGP VGYDSEDELE ESRGTLGSRA LSHDSIFIPE
110 120 130 140 150
SGQDATRPVR VFSQENVCDR IKALQLKIQC NVKMGPPPPP GGLPAKRGED
160 170 180 190 200
AGMSSEDDGL PRSPPEMSLL HDVGPGTTIK VSVVSPDHVS DSTVSARISD
210 220 230 240 250
NSLAPVADFS YPAESSSCLD NSAAKHKLQV KPRNQRSSKM RRLSSRAQSE
260 270 280 290 300
SLSDLTCTPE EEENEEKPLL EVSPEERPSS GQQDVAPDRG PEPGPPAPLP
310 320 330 340 350
PPGGARARRA RLQHSSALTA SVEEGGVPGE DPSSRPATPE LAEPESAPTL
360 370 380 390 400
RVEPPSPPEG PPNPGPDGGK QDGEAPPAGP CAPATDKAEE VVCAPEDVAS
410 420 430 440 450
PFPTAIPEGD TTPPETDPAA TSEAPSARDG PERSVPKEAE PTPPVLPDEE
460 470 480 490 500
KGPPGPAPEP EREAETEPER GAGTEPERIG TEPSTAPAPS PPAPKSCLKH
510 520 530 540 550
RPAAASEGPA ASPPLAAAES PPVEPGPGSL DAEAAAPERP KAERAEAPPA
560 570 580 590 600
GAERAAPERK AERGGAELRG AKKFSVSSCR ARPRPGVSRP LERASGRLPL
610 620 630 640 650
ARSGPVWRSE AALDDLQGLP EPQHAKPGPR KLAERGPQDS GDRAASPAGP
660 670 680 690 700
RKSPQEAAAA PGTREPCPAA QEPAPSEDRN PFPVKLRSTS LSLKYRDGAS
710 720 730 740 750
QEVKGVKRYS AEVRLERSLT VLPKEEKCPL GTAPALRGTR APSDQGKGKA
760 770 780 790 800
RPPEPLSSKP PLPRKPLLQS FTLPHQPAPP DAGPGEREPR KEPRTAEKRP
810 820 830 840 850
LRRGAEKSLP PAATGPGADG QPAPPWITVT RQKRRGTLDQ PPNQEDKPGA
860 870 880 890 900
RTLKSEPGKQ AKVPERGQEP VKQADFVRSK SFLITPVKPA VDRKQGAKLN
910 920 930 940 950
FKEGLQRGIS LSHQNLAQSA VMMEKELHQL KRASYASTDQ PSWMELARKK
960
SQAWSDMPQI IK
Length:962
Mass (Da):102,157
Last modified:November 25, 2008 - v3
Checksum:iAC2C9BFE1C41DB98
GO

Sequence cautioni

The sequence AAH68277.1 differs from that shown. Reason: Frameshift at positions 503 and 725. Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti509 – 5091P → T in AAH68277 (PubMed:15489334).Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti315 – 3151S → C.
Corresponds to variant rs3731660 [ dbSNP | Ensembl ].
VAR_047335

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC084377 Genomic DNA. No translation available.
BC068277 mRNA. Translation: AAH68277.1. Frameshift.
CCDSiCCDS42720.1.
RefSeqiNP_997245.2. NM_207362.2.
UniGeneiHs.469398.

Genome annotation databases

EnsembliENST00000397899; ENSP00000380996; ENSG00000196872.
GeneIDi343990.
KEGGihsa:343990.
UCSCiuc002szf.2. human.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC084377 Genomic DNA. No translation available.
BC068277 mRNA. Translation: AAH68277.1. Frameshift.
CCDSiCCDS42720.1.
RefSeqiNP_997245.2. NM_207362.2.
UniGeneiHs.469398.

3D structure databases

ProteinModelPortaliQ6NV74.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000380996.

PTM databases

iPTMnetiQ6NV74.
PhosphoSiteiQ6NV74.

Polymorphism and mutation databases

BioMutaiKIAA1211L.
DMDMi215274155.

Proteomic databases

EPDiQ6NV74.
MaxQBiQ6NV74.
PaxDbiQ6NV74.
PeptideAtlasiQ6NV74.
PRIDEiQ6NV74.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000397899; ENSP00000380996; ENSG00000196872.
GeneIDi343990.
KEGGihsa:343990.
UCSCiuc002szf.2. human.

Organism-specific databases

CTDi343990.
GeneCardsiKIAA1211L.
H-InvDBHIX0029975.
HGNCiHGNC:33454. KIAA1211L.
HPAiHPA051082.
HPA061678.
neXtProtiNX_Q6NV74.
PharmGKBiPA31767.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IIB6. Eukaryota.
ENOG410YAR8. LUCA.
GeneTreeiENSGT00740000115532.
HOGENOMiHOG000111324.
InParanoidiQ6NV74.
OMAiCAPATDK.
OrthoDBiEOG7WX08B.
PhylomeDBiQ6NV74.
TreeFamiTF335584.

Miscellaneous databases

GenomeRNAii343990.
PROiQ6NV74.

Gene expression databases

BgeeiQ6NV74.
CleanExiHS_C2orf55.
ExpressionAtlasiQ6NV74. baseline and differential.
GenevisibleiQ6NV74. HS.

Family and domain databases

InterProiIPR028030. DUF4592.
IPR026713. KIAA1211L.
[Graphical view]
PANTHERiPTHR22118:SF16. PTHR22118:SF16. 2 hits.
PfamiPF15262. DUF4592. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
    Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
    , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
    Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Brain.
  3. "Toward a comprehensive characterization of a human cancer cell phosphoproteome."
    Zhou H., Di Palma S., Preisinger C., Peng M., Polat A.N., Heck A.J., Mohammed S.
    J. Proteome Res. 12:260-271(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-92 AND SER-490, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.

Entry informationi

Entry nameiK121L_HUMAN
AccessioniPrimary (citable) accession number: Q6NV74
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: November 25, 2008
Last modified: July 6, 2016
This is version 84 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.