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Q6NUS6

- TECT3_HUMAN

UniProt

Q6NUS6 - TECT3_HUMAN

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Protein
Tectonic-3
Gene
TCTN3, C10orf61, TECT3, PSEC0041, UNQ1881/PRO4324
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition By similarity. May be involved in apoptosis regulation. Necessary for signal transduction through the sonic hedgehog (Shh) signaling pathway.2 Publications

GO - Biological processi

  1. apoptotic process Source: UniProtKB-KW
  2. cilium morphogenesis Source: UniProtKB
  3. smoothened signaling pathway Source: UniProtKB
Complete GO annotation...

Keywords - Biological processi

Apoptosis, Cilium biogenesis/degradation

Names & Taxonomyi

Protein namesi
Recommended name:
Tectonic-3
Gene namesi
Name:TCTN3
Synonyms:C10orf61, TECT3
ORF Names:PSEC0041, UNQ1881/PRO4324
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 10

Organism-specific databases

HGNCiHGNC:24519. TCTN3.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini23 – 581559Extracellular Reviewed prediction
Add
BLAST
Transmembranei582 – 60221Helical; Reviewed prediction
Add
BLAST
Topological domaini603 – 6075Cytoplasmic Reviewed prediction

GO - Cellular componenti

  1. extracellular vesicular exosome Source: UniProt
  2. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Involvement in diseasei

Orofaciodigital syndrome 4 (OFD4) [MIM:258860]: A form of orofaciodigital syndrome, a group of heterogeneous disorders characterized by malformations of the oral cavity, face and digits, and associated phenotypic abnormalities that lead to the delineation of various subtypes. OFD4 patients have tongue nodules, multiple frenulae, broad flat nose, hypertelorism, and short rib polydactyly with tibial dysplasia (Majewski syndrome). The presence of severe tibial aplasia differentiates OFD4 from OFD1. Additional features of cystic dysplastic kidneys and brain malformation, including occipital encephalocele, are observed in severely affected patients.
Note: The disease is caused by mutations affecting the gene represented in this entry.
Joubert syndrome 18 (JBTS18) [MIM:614815]: A form of Joubert syndrome, a disorder presenting with cerebellar ataxia, oculomotor apraxia, hypotonia, neonatal breathing abnormalities and psychomotor delay. Neuroradiologically, it is characterized by cerebellar vermian hypoplasia/aplasia, thickened and reoriented superior cerebellar peduncles, and an abnormally large interpeduncular fossa, giving the appearance of a molar tooth on transaxial slices (molar tooth sign). Additional variable features include retinal dystrophy and renal disease. JBTS18 patients have vermis agenesis and the molar tooth sign as well as severe kyphoscoliosis. Other features include intrauterine growth retardation, oral anomalies, micrognathism, polydactyly and camptodactyly, joint laxity, horseshoe kidney, and ventricular septal defect.
Note: The disease is caused by mutations affecting the gene represented in this entry. TCTN3-mutated fibroblasts from JBTS18 patients fail to respond to Shh agonists suggesting that at least some of the defects in affected individuals may be secondary to reduced Shh signaling (1 Publication).1 Publication
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti314 – 3141G → R in JBTS18. 1 Publication
VAR_068823

Keywords - Diseasei

Ciliopathy, Disease mutation, Joubert syndrome

Organism-specific databases

MIMi258860. phenotype.
614815. phenotype.
Orphaneti2754. Joubert syndrome with orofaciodigital defect.
2753. Orofaciodigital syndrome type 4.
PharmGKBiPA162405513.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2222 Reviewed prediction
Add
BLAST
Chaini23 – 607585Tectonic-3
PRO_0000229921Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi78 – 781N-linked (GlcNAc...) Reviewed prediction
Glycosylationi179 – 1791N-linked (GlcNAc...) Reviewed prediction
Glycosylationi347 – 3471N-linked (GlcNAc...) Reviewed prediction

Keywords - PTMi

Glycoprotein

Proteomic databases

MaxQBiQ6NUS6.
PaxDbiQ6NUS6.
PRIDEiQ6NUS6.

PTM databases

PhosphoSiteiQ6NUS6.

Expressioni

Gene expression databases

BgeeiQ6NUS6.
CleanExiHS_TCTN3.
GenevestigatoriQ6NUS6.

Organism-specific databases

HPAiHPA026987.

Interactioni

Subunit structurei

Part of the tectonic-like complex (also named B9 complex) By similarity.

Protein-protein interaction databases

BioGridi117565. 1 interaction.
MINTiMINT-4722379.

Structurei

3D structure databases

ProteinModelPortaliQ6NUS6.

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi90 – 10920Cys-rich
Add
BLAST

Sequence similaritiesi

Belongs to the tectonic family.

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG87342.
HOGENOMiHOG000070061.
HOVERGENiHBG094032.
InParanoidiQ6NUS6.
OrthoDBiEOG7S4X62.
PhylomeDBiQ6NUS6.
TreeFamiTF329169.

Family and domain databases

InterProiIPR011677. DUF1619.
[Graphical view]
PfamiPF07773. DUF1619. 1 hit.
[Graphical view]

Sequences (5)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 5 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q6NUS6-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

MRTPQLALLQ VFFLVFPDGV RPQPSSSPSG AVPTSLELQR GTDGGTLQSP    50
SEATATRPAV PGLPTVVPTL VTPSAPGNRT VDLFPVLPIC VCDLTPGACD 100
INCCCDRDCY LLHPRTVFSF CLPGSVRSSS WVCVDNSVIF RSNSPFPSRV 150
FMDSNGIRQF CVHVNNSNLN YFQKLQKVNA TNFQALAAEF GGESFTSTFQ 200
TQSPPSFYRA GDPILTYFPK WSVISLLRQP AGVGAGGLCA ESNPAGFLES 250
KSTTCTRFFK NLASSCTLDS ALNAASYYNF TVLKVPRSMT DPQNMEFQVP 300
VILTSQANAP LLAGNTCQNV VSQVTYEIET NGTFGIQKVS VSLGQTNLTV 350
EPGASLQQHF ILRFRAFQQS TAASLTSPRS GNPGYIVGKP LLALTDDISY 400
SMTLLQSQGN GSCSVKRHEV QFGVNAISGC KLRLKKADCS HLQQEIYQTL 450
HGRPRPEYVA IFGNADPAQK GGWTRILNRH CSISAINCTS CCLIPVSLEI 500
QVLWAYVGLL SNPQAHVSGV RFLYQCQSIQ DSQQVTEVSL TTLVNFVDIT 550
QKPQPPRGQP KMDWKWPFDF FPFKVAFSRG VFSQKCSVSP ILILCLLLLG 600
VLNLETM 607
Length:607
Mass (Da):66,157
Last modified:April 4, 2006 - v2
Checksum:i41CE275DEDF358E6
GO
Isoform 2 (identifier: Q6NUS6-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     402-443: MTLLQSQGNG...LKKADCSHLQ → VSFLELGGLL...FVHYNEVLIY
     444-607: Missing.

Note: No experimental confirmation available.

Show »
Length:443
Mass (Da):47,985
Checksum:i12499DB14EB8C0D2
GO
Isoform 3 (identifier: Q6NUS6-3) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-151: Missing.
     297-323: Missing.

Note: No experimental confirmation available. May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.

Show »
Length:429
Mass (Da):47,284
Checksum:iBA9CF7DC7490F6C3
GO
Isoform 4 (identifier: Q6NUS6-4) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     210-211: AG → VS
     212-607: Missing.

Note: No experimental confirmation available.

Show »
Length:211
Mass (Da):22,846
Checksum:iBFFB9036766D2867
GO
Isoform 5 (identifier: Q6NUS6-5) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     167-246: SNLNYFQKLQ...GLCAESNPAG → C
     297-365: Missing.

Note: No experimental confirmation available.

Show »
Length:459
Mass (Da):50,258
Checksum:i3BCD657AE2F53BDB
GO

Sequence cautioni

The sequence BAC11567.1 differs from that shown. Reason: Frameshift at position 238.
The sequence AAH68449.2 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.
The sequence ABB90564.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.
The sequence BAC87634.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.
The sequence CAI16768.2 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti314 – 3141G → R in JBTS18. 1 Publication
VAR_068823

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 151151Missing in isoform 3.
VSP_017791Add
BLAST
Alternative sequencei167 – 24680SNLNY…SNPAG → C in isoform 5.
VSP_043266Add
BLAST
Alternative sequencei210 – 2112AG → VS in isoform 4.
VSP_017792
Alternative sequencei212 – 607396Missing in isoform 4.
VSP_017793Add
BLAST
Alternative sequencei297 – 36569Missing in isoform 5.
VSP_043267Add
BLAST
Alternative sequencei297 – 32327Missing in isoform 3.
VSP_017794Add
BLAST
Alternative sequencei402 – 44342MTLLQ…CSHLQ → VSFLELGGLLQPNEKSCKGF QTYVRLAKGEEFFVHYNEVL IY in isoform 2.
VSP_017795Add
BLAST
Alternative sequencei444 – 607164Missing in isoform 2.
VSP_017796Add
BLAST

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti30 – 301G → E in BAC11567. 1 Publication
Sequence conflicti492 – 4921C → R in BAC11567. 1 Publication
Sequence conflicti516 – 5161H → Q in CAB43242. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DQ278872 mRNA. Translation: ABB90564.1. Different initiation.
AK075357 mRNA. Translation: BAC11567.1. Frameshift.
AY359022 mRNA. Translation: AAQ89381.1.
AK098295 mRNA. Translation: BAC05278.1.
AK128834 mRNA. Translation: BAC87634.1. Different initiation.
AK299141 mRNA. Translation: BAG61193.1.
AL050022 mRNA. Translation: CAB43242.2.
AL356632 Genomic DNA. Translation: CAI16768.2. Different initiation.
AL356632 Genomic DNA. Translation: CAQ07589.1.
BC009494 mRNA. Translation: AAH09494.2.
BC061582 mRNA. Translation: AAH61582.1.
BC068449 mRNA. Translation: AAH68449.2. Different initiation.
CCDSiCCDS31258.2. [Q6NUS6-1]
CCDS44461.1. [Q6NUS6-5]
PIRiT08708.
RefSeqiNP_001137445.1. NM_001143973.1. [Q6NUS6-5]
NP_056446.4. NM_015631.5. [Q6NUS6-1]
UniGeneiHs.438991.

Genome annotation databases

EnsembliENST00000265993; ENSP00000265993; ENSG00000119977.
ENST00000371209; ENSP00000360253; ENSG00000119977. [Q6NUS6-2]
ENST00000371217; ENSP00000360261; ENSG00000119977. [Q6NUS6-1]
ENST00000430368; ENSP00000387567; ENSG00000119977. [Q6NUS6-5]
GeneIDi26123.
KEGGihsa:26123.
UCSCiuc001klb.4. human. [Q6NUS6-1]
uc001kld.3. human. [Q6NUS6-2]
uc009xux.1. human. [Q6NUS6-3]
uc010qoi.2. human. [Q6NUS6-5]

Polymorphism databases

DMDMi91208025.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DQ278872 mRNA. Translation: ABB90564.1 . Different initiation.
AK075357 mRNA. Translation: BAC11567.1 . Frameshift.
AY359022 mRNA. Translation: AAQ89381.1 .
AK098295 mRNA. Translation: BAC05278.1 .
AK128834 mRNA. Translation: BAC87634.1 . Different initiation.
AK299141 mRNA. Translation: BAG61193.1 .
AL050022 mRNA. Translation: CAB43242.2 .
AL356632 Genomic DNA. Translation: CAI16768.2 . Different initiation.
AL356632 Genomic DNA. Translation: CAQ07589.1 .
BC009494 mRNA. Translation: AAH09494.2 .
BC061582 mRNA. Translation: AAH61582.1 .
BC068449 mRNA. Translation: AAH68449.2 . Different initiation.
CCDSi CCDS31258.2. [Q6NUS6-1 ]
CCDS44461.1. [Q6NUS6-5 ]
PIRi T08708.
RefSeqi NP_001137445.1. NM_001143973.1. [Q6NUS6-5 ]
NP_056446.4. NM_015631.5. [Q6NUS6-1 ]
UniGenei Hs.438991.

3D structure databases

ProteinModelPortali Q6NUS6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 117565. 1 interaction.
MINTi MINT-4722379.

PTM databases

PhosphoSitei Q6NUS6.

Polymorphism databases

DMDMi 91208025.

Proteomic databases

MaxQBi Q6NUS6.
PaxDbi Q6NUS6.
PRIDEi Q6NUS6.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000265993 ; ENSP00000265993 ; ENSG00000119977 .
ENST00000371209 ; ENSP00000360253 ; ENSG00000119977 . [Q6NUS6-2 ]
ENST00000371217 ; ENSP00000360261 ; ENSG00000119977 . [Q6NUS6-1 ]
ENST00000430368 ; ENSP00000387567 ; ENSG00000119977 . [Q6NUS6-5 ]
GeneIDi 26123.
KEGGi hsa:26123.
UCSCi uc001klb.4. human. [Q6NUS6-1 ]
uc001kld.3. human. [Q6NUS6-2 ]
uc009xux.1. human. [Q6NUS6-3 ]
uc010qoi.2. human. [Q6NUS6-5 ]

Organism-specific databases

CTDi 26123.
GeneCardsi GC10M097414.
GeneReviewsi TCTN3.
HGNCi HGNC:24519. TCTN3.
HPAi HPA026987.
MIMi 258860. phenotype.
613847. gene.
614815. phenotype.
neXtProti NX_Q6NUS6.
Orphaneti 2754. Joubert syndrome with orofaciodigital defect.
2753. Orofaciodigital syndrome type 4.
PharmGKBi PA162405513.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG87342.
HOGENOMi HOG000070061.
HOVERGENi HBG094032.
InParanoidi Q6NUS6.
OrthoDBi EOG7S4X62.
PhylomeDBi Q6NUS6.
TreeFami TF329169.

Miscellaneous databases

GenomeRNAii 26123.
NextBioi 48139.
PROi Q6NUS6.
SOURCEi Search...

Gene expression databases

Bgeei Q6NUS6.
CleanExi HS_TCTN3.
Genevestigatori Q6NUS6.

Family and domain databases

InterProi IPR011677. DUF1619.
[Graphical view ]
Pfami PF07773. DUF1619. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Tectonic, a novel regulator of the Hedgehog pathway required for both activation and inhibition."
    Reiter J.F., Skarnes W.C.
    Genes Dev. 20:22-27(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 3; 4 AND 5).
    Tissue: Teratocarcinoma, Testis and Uterus.
  4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Tissue: Brain.
  5. "The DNA sequence and comparative analysis of human chromosome 10."
    Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L., Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K., Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L., Taylor A., Battles J.
    , Bird C.P., Ainscough R., Almeida J.P., Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Cahill P., Camire D., Carter N.P., Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S., Corby N., Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L., Frankish A., Frankland J.A., Garner P., Garnett J., Gribble S., Griffiths C., Grocock R., Gustafson E., Hammond S., Harley J.L., Hart E., Heath P.D., Ho T.P., Hopkins B., Horne J., Howden P.J., Huckle E., Hynds C., Johnson C., Johnson D., Kana A., Kay M., Kimberley A.M., Kershaw J.K., Kokkinaki M., Laird G.K., Lawlor S., Lee H.M., Leongamornlert D.A., Laird G., Lloyd C., Lloyd D.M., Loveland J., Lovell J., McLaren S., McLay K.E., McMurray A., Mashreghi-Mohammadi M., Matthews L., Milne S., Nickerson T., Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A., Ross M.T., Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W., Tracey A., Tromans A., Tsolas J., Wall M., Walsh J., Wang H., Weinstock K., West A.P., Willey D.L., Whitehead S.L., Wilming L., Wray P.W., Young L., Chen Y., Lovering R.C., Moschonas N.K., Siebert R., Fechtel K., Bentley D., Durbin R.M., Hubbard T., Doucette-Stamm L., Beck S., Smith D.R., Rogers J.
    Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 30-607 (ISOFORM 2).
    Tissue: Lung, Testis and Uterus.
  7. "Identification of novel regulators of apoptosis using a high-throughput cell-based screen."
    Park K.M., Kang E., Jeon Y.-J., Kim N., Kim N.-S., Yoo H.-S., Yeom Y.I., Kim S.J.
    Mol. Cells 23:170-174(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
  8. Cited for: FUNCTION, INVOLVEMENT IN OFDS4, VARIANT JBTS18 ARG-314.

Entry informationi

Entry nameiTECT3_HUMAN
AccessioniPrimary (citable) accession number: Q6NUS6
Secondary accession number(s): A6NIC8
, B0QZ90, B4DR81, Q6P7P3, Q6UW27, Q6ZQQ0, Q8N7K1, Q8NBQ0, Q96GF7, Q9Y3U1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: April 4, 2006
Last modified: September 3, 2014
This is version 82 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 10
    Human chromosome 10: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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