Reviewed, UniProtKB/Swiss-Prot Q6NTN0 (CYC1B_XENLA)

Names and origin

Protein names

Recommended name:
    Cytochrome c, somatic B

Gene names

Name:

cycs-B

Organism

Xenopus laevis (African clawed frog)

Taxonomic identifier

8355 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Amphibia › Batrachia › Anura › Mesobatrachia › Pipoidea › Pipidae › Xenopodinae › Xenopus › Xenopus

Protein attributes

Sequence length	105 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain By similarity.
Subcellular location	Mitochondrion matrix By similarity.
Post-translational modification	Binds 1 heme group per subunit By similarity.
Sequence similarities	Belongs to the cytochrome c family.

Ontologies

Keywords
Biological process	Electron transport Respiratory chain Transport
Cellular component	Mitochondrion
Ligand	Heme Iron Metal-binding
PTM	Acetylation
Gene Ontology (GO)
Biological process	electron transport chain Inferred from electronic annotation. Source: UniProtKB-KW transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	mitochondrial matrix Inferred from electronic annotation. Source: UniProtKB-SubCell respiratory chain Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	electron carrier activity Inferred from electronic annotation. Source: InterPro heme binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Initiator methionine	1	1	Removed By similarity
	Chain	2 – 105	104	Cytochrome c, somatic B		PRO_0000266016
Sites
	Metal binding	19	1	Iron (heme axial ligand) By similarity
	Metal binding	81	1	Iron (heme axial ligand) By similarity
	Binding site	15	1	Heme (covalent) By similarity
	Binding site	18	1	Heme (covalent) By similarity
Amino acid modifications
	Modified residue	2	1	N-acetylglycine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q6NTN0-1 [UniParc]. Last modified January 23, 2007. Version 3. Checksum: 23556177D9700EEF	FASTA	105	11,694
	10 20 30 40 50 60 MGDAGKGKKI FIQKCAQCHT VEKTGKHKTG PNLWGLFGRK TGQAPGFSYT DANKSKGIVW 70 80 90 100 GEETLLEYLE NPKKYIPGTK MIFAGIKKKN ERLDLIAYLK KSTSE

References

[1]	NIH - Xenopus Gene Collection (XGC) project Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Embryo.

Web resources

Protein Spotlight

Life shuttle - Issue 76 of November 2006

Cross-references

Sequence databases
EMBLGenBankDDBJ	BC068929 mRNA. Translation: AAH68929.1. Different initiation.
UniGene	Xl.46729
3D structure databases
HSSP	HSSP built from PDB template 2B4Z based on UniProtKB P62894.
SMR	Q6NTN0. Positions 2-104.
ModBase	Search...
Phylogenomic databases
HOVERGEN	Q6NTN0.
Family and domain databases
InterPro	IPR002327. Cyt_c_1A/1B. IPR003088. Cyt_c_I. IPR009056. Cyt_c_monohaem. [Graphical view]
Gene3D	G3DSA:1.10.760.10. Cytochrome_c_R. 1 hit.
PANTHER	PTHR11961. Cyt_CIAB. 1 hit.
Pfam	PF00034. Cytochrom_C. 1 hit. [Graphical view]
PRINTS	PR00604. CYTCHRMECIAB.
PROSITE	PS51007. CYTC. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CYC1B_XENLA

Accession

Primary (citable) accession number: Q6NTN0

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 12, 2006
Last sequence update:	January 23, 2007
Last modified:	November 24, 2009
This is version 39 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

Xenopus annotation project