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Protein
Submitted name:

B-cell leukemia/lymphoma 2

Gene

Bcl2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processApoptosisPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
B-cell leukemia/lymphoma 2Imported
Submitted name:
B-cell leukemia/lymphoma 2, isoform CRA_aImported
Gene namesi
Name:Bcl2Imported
ORF Names:mCG_128637Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:88138. Bcl2.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSMUSG00000057329.

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini11 – 30BH4_2InterPro annotationAdd BLAST20

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi11 – 30BH4PROSITE-ProRule annotationAdd BLAST20

Phylogenomic databases

eggNOGiKOG4728. Eukaryota.
ENOG41123S0. LUCA.
HOVERGENiHBG004472.

Family and domain databases

InterProiView protein in InterPro
IPR013278. Apop_reg_Bcl2.
IPR002475. Bcl2-like.
IPR020717. Bcl2_BH1_motif_CS.
IPR020728. Bcl2_BH3_motif_CS.
IPR003093. Bcl2_BH4.
IPR020731. Bcl2_BH4_motif_CS.
IPR026298. Blc2_fam.
PANTHERiPTHR11256. PTHR11256. 1 hit.
PTHR11256:SF55. PTHR11256:SF55. 1 hit.
PfamiView protein in Pfam
PF00452. Bcl-2. 1 hit.
PF02180. BH4. 1 hit.
PRINTSiPR01863. APOPREGBCL2.
PR01862. BCL2FAMILY.
SMARTiView protein in SMART
SM00265. BH4. 1 hit.
SUPFAMiSSF56854. SSF56854. 1 hit.
PROSITEiView protein in PROSITE
PS50062. BCL2_FAMILY. 1 hit.
PS01080. BH1. 1 hit.
PS01259. BH3. 1 hit.
PS01260. BH4_1. 1 hit.
PS50063. BH4_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6NTH7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQAGRTGYD NREIVMKYIH YKLSQRGYEW DAGDADAAPL GAAPTPGIFS
60 70 80 90 100
FQPESNPMPA VHRDMAARTS PLRPLVATAG PALSPVPPVV HLTLRRAGDD
110 120 130 140 150
FSRRYRRDFA EMSSQLHLTP FTARGRFATV VEELFRDGVN WGRIVAFFEF
160 170 180 190
GGVMCVESVN REMSPLVDNI ALWMTEYLNR HLHTWIQDNG GWVGACLVE
Length:199
Mass (Da):22,281
Last modified:July 5, 2004 - v1
Checksum:iF13C8037262BA955
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC068988 mRNA. Translation: AAH68988.1.
CH466520 Genomic DNA. Translation: EDL39861.1.
RefSeqiNP_803129.2. NM_177410.3.
UniGeneiMm.257460.

Genome annotation databases

GeneIDi12043.
UCSCiuc011wqb.2. mouse.

Similar proteinsi

Entry informationi

Entry nameiQ6NTH7_MOUSE
AccessioniPrimary (citable) accession number: Q6NTH7
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: August 30, 2017
This is version 103 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)