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Protein
Submitted name:

HNRNPL protein

Gene

HNRNPL

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
HNRNPL proteinImported
Gene namesi
Name:HNRNPLImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA162391389.

PTM / Processingi

Proteomic databases

PaxDbiQ6NTA2.
PRIDEiQ6NTA2.

Expressioni

Gene expression databases

BgeeiQ6NTA2.
GenevisibleiQ6NTA2. HS.

Interactioni

Protein-protein interaction databases

IntActiQ6NTA2. 1 interaction.
MINTiMINT-5001734.
STRINGi9606.ENSP00000221419.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini85 – 15975RRM (RNA recognition motif)InterPro annotationAdd
BLAST
Domaini176 – 25378RRM (RNA recognition motif)InterPro annotationAdd
BLAST
Domaini365 – 43975RRM (RNA recognition motif)InterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG1456. Eukaryota.
ENOG410XQHN. LUCA.
HOVERGENiHBG105786.
KOiK13159.

Family and domain databases

Gene3Di3.30.70.330. 4 hits.
InterProiIPR006536. HnRNP-L/PTB.
IPR012677. Nucleotide-bd_a/b_plait.
IPR000504. RRM_dom.
[Graphical view]
PfamiPF00076. RRM_1. 2 hits.
[Graphical view]
SMARTiSM00360. RRM. 3 hits.
[Graphical view]
SUPFAMiSSF54928. SSF54928. 3 hits.
TIGRFAMsiTIGR01649. hnRNP-L_PTB. 1 hit.
PROSITEiPS50102. RRM. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q6NTA2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
QRQQPDEQRR RSGAMVKMAA AGGGGGGGRY YGGGSEGGRA PKRLKTDNAG
60 70 80 90 100
DQHGGGGGGG GGAGAAGGGG GGENYDDPHK TPASPVVHIR GLIDGVVEAD
110 120 130 140 150
LVEALQEFGP ISYVVVMPKK RQALVEFEDV LGACNAVNYA ADNQIYIAGH
160 170 180 190 200
PAFVNYSTSQ KISRPGDSDD SRSVNSVLLF TILNPIYSIT TDVLYTICNP
210 220 230 240 250
CGPVQRIVIF RKNGVQAMVE FDSVQSAQRA KASLNGADIY SGCCTLKIEY
260 270 280 290 300
AKPTRLNVFK NDQDTWDYTN PNLSGQGDPG SNPNKRQRQP PLLGDHPAEY
310 320 330 340 350
GGPHGGYHSH YHDEGYGPPP PHYEGRRMGP PVGGHRRGPS RYGPQYGHPP
360 370 380 390 400
PPPPPPEYGP HADSPVLMVY GLDQSKMNCD RVFNVFCLYG NVEKVKFMKS
410 420 430 440 450
KPGAAMVEMA DGYAVDRAIT HLNNNFMFGQ KLNVCVSKQP AIMPGQSYGL
460 470 480 490 500
EDGSCSYKDF SESRNNRFST PEQAAKNRIQ HPSNVLHFFN APLEVTEENF
510 520 530 540 550
FEICDELGVK RPSSVKVFSG KSERSSSGLL EWESKSDALE TLGFLNHYQM
560 570
KNPNGPYPYT LKLCFSTAQH AS
Length:572
Mass (Da):61,927
Last modified:December 16, 2008 - v2
Checksum:i5E5EB8F6773DC522
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC069184 mRNA. Translation: AAH69184.2.
RefSeqiNP_001005335.1. NM_001005335.1.
NP_001524.2. NM_001533.2.
UniGeneiHs.644906.

Genome annotation databases

GeneIDi3191.
KEGGihsa:3191.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC069184 mRNA. Translation: AAH69184.2.
RefSeqiNP_001005335.1. NM_001005335.1.
NP_001524.2. NM_001533.2.
UniGeneiHs.644906.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ6NTA2. 1 interaction.
MINTiMINT-5001734.
STRINGi9606.ENSP00000221419.

Proteomic databases

PaxDbiQ6NTA2.
PRIDEiQ6NTA2.

Protocols and materials databases

DNASUi3191.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi3191.
KEGGihsa:3191.

Organism-specific databases

CTDi3191.
PharmGKBiPA162391389.

Phylogenomic databases

eggNOGiKOG1456. Eukaryota.
ENOG410XQHN. LUCA.
HOVERGENiHBG105786.
KOiK13159.

Miscellaneous databases

ChiTaRSiHNRNPL. human.
GenomeRNAii3191.

Gene expression databases

BgeeiQ6NTA2.
GenevisibleiQ6NTA2. HS.

Family and domain databases

Gene3Di3.30.70.330. 4 hits.
InterProiIPR006536. HnRNP-L/PTB.
IPR012677. Nucleotide-bd_a/b_plait.
IPR000504. RRM_dom.
[Graphical view]
PfamiPF00076. RRM_1. 2 hits.
[Graphical view]
SMARTiSM00360. RRM. 3 hits.
[Graphical view]
SUPFAMiSSF54928. SSF54928. 3 hits.
TIGRFAMsiTIGR01649. hnRNP-L_PTB. 1 hit.
PROSITEiPS50102. RRM. 3 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: UterusImported.

Entry informationi

Entry nameiQ6NTA2_HUMAN
AccessioniPrimary (citable) accession number: Q6NTA2
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: December 16, 2008
Last modified: June 8, 2016
This is version 101 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.