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Q6NSI1 (AR26L_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 77. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (4) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative ankyrin repeat domain-containing protein 26-like protein
Gene names
Name:ANKRD26P1
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length321 AA.
Sequence statusComplete.
Protein existenceUncertain

General annotation (Comments)

Sequence similarities

Contains 5 ANK repeats.

Caution

Could be the product of a pseudogene.

Ontologies

Keywords
   Coding sequence diversityPolymorphism
   DomainANK repeat
Repeat
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 321321Putative ankyrin repeat domain-containing protein 26-like protein
PRO_0000326201

Regions

Repeat48 – 7831ANK 1
Repeat82 – 11130ANK 2
Repeat115 – 14430ANK 3
Repeat148 – 17730ANK 4
Repeat181 – 21030ANK 5

Natural variations

Natural variant2651K → T. Ref.2
Corresponds to variant rs1436436 [ dbSNP | Ensembl ].
VAR_040003

Sequences

Sequence LengthMass (Da)Tools
Q6NSI1 [UniParc].

Last modified October 5, 2010. Version 2.
Checksum: 7FDB6EE37D716EB4

FASTA32135,437
        10         20         30         40         50         60 
MRRSSGFGGQ KGQGPSCSFT GCWCCRGDDV AESDDSPFAQ CGYNIQEKHL GKLHRAASRG 

        70         80         90        100        110        120 
EVSKVECILS SGSADLDERD KKKRTALHLA CANGHPEVVA LLVDRGCQLD VFDNKNRTAL 

       130        140        150        160        170        180 
LKAVQCQEEE CATILLEHGA DPDLPDVYGN TTLHYAIYNE DIPMTKKLLL HHANIESANK 

       190        200        210        220        230        240 
DELTPFLLAV HEQKQQMEDF LRKQKENLTA VKLESIHQVM SEYKENETPR NPQNSNPEGT 

       250        260        270        280        290        300 
SNKMACLGEG AAGAKVDEIP GNPVKRLFNK PSIDDSRPMS ANEDFDFDTE EKATEPANGK 

       310        320 
RQNGMGIIES APQEHTNNEN I 

« Hide

References

[1]"The sequence and analysis of duplication-rich human chromosome 16."
Martin J., Han C., Gordon L.A., Terry A., Prabhakar S., She X., Xie G., Hellsten U., Chan Y.M., Altherr M., Couronne O., Aerts A., Bajorek E., Black S., Blumer H., Branscomb E., Brown N.C., Bruno W.J. expand/collapse author list , Buckingham J.M., Callen D.F., Campbell C.S., Campbell M.L., Campbell E.W., Caoile C., Challacombe J.F., Chasteen L.A., Chertkov O., Chi H.C., Christensen M., Clark L.M., Cohn J.D., Denys M., Detter J.C., Dickson M., Dimitrijevic-Bussod M., Escobar J., Fawcett J.J., Flowers D., Fotopulos D., Glavina T., Gomez M., Gonzales E., Goodstein D., Goodwin L.A., Grady D.L., Grigoriev I., Groza M., Hammon N., Hawkins T., Haydu L., Hildebrand C.E., Huang W., Israni S., Jett J., Jewett P.B., Kadner K., Kimball H., Kobayashi A., Krawczyk M.-C., Leyba T., Longmire J.L., Lopez F., Lou Y., Lowry S., Ludeman T., Manohar C.F., Mark G.A., McMurray K.L., Meincke L.J., Morgan J., Moyzis R.K., Mundt M.O., Munk A.C., Nandkeshwar R.D., Pitluck S., Pollard M., Predki P., Parson-Quintana B., Ramirez L., Rash S., Retterer J., Ricke D.O., Robinson D.L., Rodriguez A., Salamov A., Saunders E.H., Scott D., Shough T., Stallings R.L., Stalvey M., Sutherland R.D., Tapia R., Tesmer J.G., Thayer N., Thompson L.S., Tice H., Torney D.C., Tran-Gyamfi M., Tsai M., Ulanovsky L.E., Ustaszewska A., Vo N., White P.S., Williams A.L., Wills P.L., Wu J.-R., Wu K., Yang J., DeJong P., Bruce D., Doggett N.A., Deaven L., Schmutz J., Grimwood J., Richardson P., Rokhsar D.S., Eichler E.E., Gilna P., Lucas S.M., Myers R.M., Rubin E.M., Pennacchio L.A.
Nature 432:988-994(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANT THR-265.
Tissue: Testis.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC092368 Genomic DNA. No translation available.
AC106819 Genomic DNA. No translation available.
BC070117 mRNA. No translation available.
UniGeneHs.97414.

3D structure databases

ProteinModelPortalQ6NSI1.
SMRQ6NSI1. Positions 7-267.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING9606.ENSP00000331873.

Polymorphism databases

DMDM306526200.

Proteomic databases

PaxDbQ6NSI1.
PRIDEQ6NSI1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

GeneCardsGC16M046503.
HGNCHGNC:32955. ANKRD26P1.
neXtProtNX_Q6NSI1.
GenAtlasSearch...

Phylogenomic databases

eggNOGCOG0666.
HOGENOMHOG000013154.
InParanoidQ6NSI1.
PhylomeDBQ6NSI1.

Gene expression databases

GenevestigatorQ6NSI1.

Family and domain databases

Gene3D1.25.40.20. 2 hits.
InterProIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
[Graphical view]
PfamPF12796. Ank_2. 1 hit.
PF13606. Ank_3. 1 hit.
[Graphical view]
PRINTSPR01415. ANKYRIN.
SMARTSM00248. ANK. 4 hits.
[Graphical view]
SUPFAMSSF48403. SSF48403. 1 hit.
PROSITEPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 3 hits.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAR26L_HUMAN
AccessionPrimary (citable) accession number: Q6NSI1
Entry history
Integrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: October 5, 2010
Last modified: April 16, 2014
This is version 77 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

Human polymorphisms and disease mutations

Index of human polymorphisms and disease mutations

Human entries with polymorphisms or disease mutations

List of human entries with polymorphisms or disease mutations

Human chromosome 16

Human chromosome 16: entries, gene names and cross-references to MIM