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Protein
Submitted name:

Protein Zfp366

Gene

Zfp366

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. estrogen receptor binding Source: MGI
  2. metal ion binding Source: InterPro
  3. nucleic acid binding Source: InterPro
  4. transcription corepressor activity Source: MGI

GO - Biological processi

  1. negative regulation of intracellular estrogen receptor signaling pathway Source: MGI
  2. negative regulation of transcription from RNA polymerase II promoter Source: MGI
  3. response to estrogen Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Protein Zfp366Imported
Submitted name:
Zinc finger protein 366Imported
Gene namesi
Name:Zfp366Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 13

Organism-specific databases

MGIiMGI:2178429. Zfp366.

Subcellular locationi

GO - Cellular componenti

  1. nucleus Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

GenevestigatoriQ6NS86.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000060040.

Structurei

3D structure databases

ProteinModelPortaliQ6NS86.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiCOG5048.
GeneTreeiENSGT00750000117653.
HOGENOMiHOG000138030.
HOVERGENiHBG055962.
OMAiHMMQHSE.
OrthoDBiEOG7MPRDM.
TreeFamiTF331510.

Family and domain databases

Gene3Di3.30.160.60. 11 hits.
InterProiIPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF00096. zf-C2H2. 6 hits.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 11 hits.
[Graphical view]
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 11 hits.
PS50157. ZINC_FINGER_C2H2_2. 11 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6NS86-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MQKAMKMVKD EDGPLNAAAK SIPSFPHCLQ PEASRGKAPQ RHPFPEALRG
60 70 80 90 100
PFSQFRYEPS PGDLDGFPEV FEGGGSRKRK SMPTKVPYTH PAEEASIAQE
110 120 130 140 150
SKSLGPPNLT LLFPQPQRPK CDSQMIDLCN VGLQFYRTLE HLGGKPVKQE
160 170 180 190 200
PVKPSAMWPQ PTPPAFLPAP YPYYPKVHPG LMFPFFVPSS SPFPFSRHTF
210 220 230 240 250
LPKQPPEPVL PRKVEPLESE ETKQKVERVD VNVQIDDSYY VDVGGAQKRW
260 270 280 290 300
QCPTCEKSYT SKYNLVTHIL GHSGIKPHAC SRCGKLFKQL SHLHTHMLTH
310 320 330 340 350
QGTRPHKCQV CHKAFTQTSH LKRHMMQHSE VKPHNCRVCS RGFAYPSELK
360 370 380 390 400
AHEAKHASGR ENICVECGLD FPTLAQLKRH LTTHRGPIQY NCSECDKTFQ
410 420 430 440 450
YPSQLQNHMM KHKDIRPYIC SECGMEFVQP HHLKQHSLTH KGVKEHKCGI
460 470 480 490 500
CGREFTLLAN MKRHVLIHTN IRAYQCHLCY KSFVQKQTLK AHMIVHSDVK
510 520 530 540 550
PFKCKLCGKE FNRMHNLMGH LHLHSDSKPF KCLYCPSKFT LKGNLTRHMK
560 570 580 590 600
VKHGVMERGL HSQGLGRGRL VLVQSAGVLR NLEQEEPFDL SQKRSANGPM
610 620 630 640 650
FQSDVDSTQD CLCQEEEEEA GEEDNCYEVE PYSPSLAPES QQLCAPEDLS
660 670 680 690 700
TKQEQTLQDP GEGCRDQDAP EEQQEDRSED HEGSDIDCEG KDIDCAIREE
710 720 730 740
RLSSRLLQSG GQGPSFSDYL YFKHRDEGLK ELLERKMEKQ AVLLGI
Length:746
Mass (Da):84,826
Last modified:July 5, 2004 - v1
Checksum:i428CD35E52054AEA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC128670 Genomic DNA. No translation available.
BC070399 mRNA. Translation: AAH70399.1.
RefSeqiNP_001004149.1. NM_001004149.1.
UniGeneiMm.343207.

Genome annotation databases

EnsembliENSMUST00000056558; ENSMUSP00000060040; ENSMUSG00000050919.
GeneIDi238803.
KEGGimmu:238803.
UCSCiuc007rpl.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC128670 Genomic DNA. No translation available.
BC070399 mRNA. Translation: AAH70399.1.
RefSeqiNP_001004149.1. NM_001004149.1.
UniGeneiMm.343207.

3D structure databases

ProteinModelPortaliQ6NS86.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000060040.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000056558; ENSMUSP00000060040; ENSMUSG00000050919.
GeneIDi238803.
KEGGimmu:238803.
UCSCiuc007rpl.1. mouse.

Organism-specific databases

CTDi238803.
MGIiMGI:2178429. Zfp366.

Phylogenomic databases

eggNOGiCOG5048.
GeneTreeiENSGT00750000117653.
HOGENOMiHOG000138030.
HOVERGENiHBG055962.
OMAiHMMQHSE.
OrthoDBiEOG7MPRDM.
TreeFamiTF331510.

Miscellaneous databases

ChiTaRSiZfp366. mouse.
NextBioi383893.
PROiQ6NS86.
SOURCEiSearch...

Gene expression databases

GenevestigatoriQ6NS86.

Family and domain databases

Gene3Di3.30.160.60. 11 hits.
InterProiIPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF00096. zf-C2H2. 6 hits.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 11 hits.
[Graphical view]
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 11 hits.
PS50157. ZINC_FINGER_C2H2_2. 11 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6Imported.
    Tissue: BrainImported.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  3. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiQ6NS86_MOUSE
AccessioniPrimary (citable) accession number: Q6NS86
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: February 4, 2015
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.