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Q6NRQ7 (SSU72_XENLA) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
RNA polymerase II subunit A C-terminal domain phosphatase SSU72

Short name=CTD phosphatase SSU72
EC=3.1.3.16
Gene names
Name:ssu72
OrganismXenopus laevis (African clawed frog)
Taxonomic identifier8355 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Protein attributes

Sequence length194 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

May be involved in the C-terminal domain of RNA polymerase II dephosphorylation, RNA processing and termination By similarity.

Catalytic activity

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Subcellular location

Nucleus By similarity. Cytoplasm By similarity. Note: Predominantly in the cytosol By similarity.

Sequence similarities

Belongs to the SSU72 phosphatase family.

Ontologies

Keywords
   Biological processmRNA processing
   Cellular componentCytoplasm
Nucleus
   DomainCoiled coil
   Molecular functionHydrolase
Protein phosphatase
Gene Ontology (GO)
   Biological_processmRNA processing

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

nucleus

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionphosphoprotein phosphatase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 194194RNA polymerase II subunit A C-terminal domain phosphatase SSU72
PRO_0000330017

Regions

Coiled coil160 – 18627 Potential

Experimental info

Sequence conflict311F → I in AAH98966. Ref.1
Sequence conflict911I → V in AAH98966. Ref.1
Sequence conflict1781E → D in AAH98966. Ref.1

Sequences

Sequence LengthMass (Da)Tools
Q6NRQ7 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 92B269CB832A2EC6

FASTA19422,681
        10         20         30         40         50         60 
MPTAPLRVAV VCSSNQNRSM EAHNILSKRS FNVRSFGTGT HVKLPGPAPD KPNVYDFKTT 

        70         80         90        100        110        120 
YEQMYSDLLK KDKELYTQNG ILHMLDRNRR IKPRPERFQN CKDYFDLVIT CEERVYDQVV 

       130        140        150        160        170        180 
EELNSREQET CQPVHVINVD IQDNHEEATL GAFLICELCQ CIQHTEDMEN EIDELLQEFE 

       190 
DKSGRTFLHT ICFY 

« Hide

References

[1]NIH - Xenopus Gene Collection (XGC) project
Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Embryo.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BC070675 mRNA. Translation: AAH70675.1.
BC098966 mRNA. Translation: AAH98966.1.
RefSeqNP_001084864.1. NM_001091395.1.
NP_001089572.1. NM_001096103.1.
UniGeneXl.48475.
Xl.9702.

3D structure databases

ProteinModelPortalQ6NRQ7.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID431913.
734628.
KEGGxla:431913.
xla:734628.

Organism-specific databases

CTD29101.
XenbaseXB-GENE-5725684. ssu72.

Phylogenomic databases

HOVERGENHBG059831.
KOK15544.

Family and domain databases

InterProIPR006811. RNA_pol_II_suA.
[Graphical view]
PANTHERPTHR20383. PTHR20383. 1 hit.
PfamPF04722. Ssu72. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSSU72_XENLA
AccessionPrimary (citable) accession number: Q6NRQ7
Secondary accession number(s): Q4KLW8
Entry history
Integrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: July 5, 2004
Last modified: April 16, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families