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Q6NRQ7

- SSU72_XENLA

UniProt

Q6NRQ7 - SSU72_XENLA

Protein

RNA polymerase II subunit A C-terminal domain phosphatase SSU72

Gene

ssu72

Organism
Xenopus laevis (African clawed frog)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 41 (01 Oct 2014)
      Sequence version 1 (05 Jul 2004)
      Previous versions | rss
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    Functioni

    May be involved in the C-terminal domain of RNA polymerase II dephosphorylation, RNA processing and termination.By similarity

    Catalytic activityi

    [a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

    GO - Molecular functioni

    1. phosphoprotein phosphatase activity Source: UniProtKB-KW

    GO - Biological processi

    1. mRNA processing Source: UniProtKB-KW

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Keywords - Biological processi

    mRNA processing

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    RNA polymerase II subunit A C-terminal domain phosphatase SSU72 (EC:3.1.3.16)
    Short name:
    CTD phosphatase SSU72
    Gene namesi
    Name:ssu72
    OrganismiXenopus laevis (African clawed frog)
    Taxonomic identifieri8355 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

    Organism-specific databases

    XenbaseiXB-GENE-5725684. ssu72.

    Subcellular locationi

    Nucleus By similarity. Cytoplasm By similarity
    Note: Predominantly in the cytosol.By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    2. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm, Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 194194RNA polymerase II subunit A C-terminal domain phosphatase SSU72PRO_0000330017Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliQ6NRQ7.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Coiled coil

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Coiled coili160 – 18627Sequence AnalysisAdd
    BLAST

    Sequence similaritiesi

    Belongs to the SSU72 phosphatase family.Curated

    Keywords - Domaini

    Coiled coil

    Phylogenomic databases

    HOVERGENiHBG059831.
    KOiK15544.

    Family and domain databases

    InterProiIPR006811. RNA_pol_II_suA.
    [Graphical view]
    PANTHERiPTHR20383. PTHR20383. 1 hit.
    PfamiPF04722. Ssu72. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q6NRQ7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPTAPLRVAV VCSSNQNRSM EAHNILSKRS FNVRSFGTGT HVKLPGPAPD    50
    KPNVYDFKTT YEQMYSDLLK KDKELYTQNG ILHMLDRNRR IKPRPERFQN 100
    CKDYFDLVIT CEERVYDQVV EELNSREQET CQPVHVINVD IQDNHEEATL 150
    GAFLICELCQ CIQHTEDMEN EIDELLQEFE DKSGRTFLHT ICFY 194
    Length:194
    Mass (Da):22,681
    Last modified:July 5, 2004 - v1
    Checksum:i92B269CB832A2EC6
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti31 – 311F → I in AAH98966. 1 PublicationCurated
    Sequence conflicti91 – 911I → V in AAH98966. 1 PublicationCurated
    Sequence conflicti178 – 1781E → D in AAH98966. 1 PublicationCurated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC070675 mRNA. Translation: AAH70675.1.
    BC098966 mRNA. Translation: AAH98966.1.
    RefSeqiNP_001084864.1. NM_001091395.1.
    NP_001089572.1. NM_001096103.1.
    UniGeneiXl.48475.
    Xl.9702.

    Genome annotation databases

    GeneIDi431913.
    734628.
    KEGGixla:431913.
    xla:734628.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC070675 mRNA. Translation: AAH70675.1 .
    BC098966 mRNA. Translation: AAH98966.1 .
    RefSeqi NP_001084864.1. NM_001091395.1.
    NP_001089572.1. NM_001096103.1.
    UniGenei Xl.48475.
    Xl.9702.

    3D structure databases

    ProteinModelPortali Q6NRQ7.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 431913.
    734628.
    KEGGi xla:431913.
    xla:734628.

    Organism-specific databases

    CTDi 29101.
    Xenbasei XB-GENE-5725684. ssu72.

    Phylogenomic databases

    HOVERGENi HBG059831.
    KOi K15544.

    Family and domain databases

    InterProi IPR006811. RNA_pol_II_suA.
    [Graphical view ]
    PANTHERi PTHR20383. PTHR20383. 1 hit.
    Pfami PF04722. Ssu72. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. NIH - Xenopus Gene Collection (XGC) project
      Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Embryo.

    Entry informationi

    Entry nameiSSU72_XENLA
    AccessioniPrimary (citable) accession number: Q6NRQ7
    Secondary accession number(s): Q4KLW8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 29, 2008
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 41 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3