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Protein

Calmodulin-binding transcription activator 2

Gene

CMTA2

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Regulates transcriptional activity in response to calcium signals. Binds to the consensus sequence 5'-[ACG]CGCG[GTC]-3'.3 Publications

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi15 – 141CG-1PROSITE-ProRule annotationAdd BLAST127

GO - Molecular functioni

GO - Biological processi

  • cellular response to aluminum ion Source: TAIR
  • positive regulation of transcription, DNA-templated Source: TAIR
  • positive regulation of transcription from RNA polymerase II promoter Source: GO_Central
  • regulation of transcription, DNA-templated Source: TAIR
  • response to cold Source: TAIR

Keywordsi

Molecular functionActivator, Calmodulin-binding, DNA-binding
Biological processStress response, Transcription, Transcription regulation
LigandCalcium

Names & Taxonomyi

Protein namesi
Recommended name:
Calmodulin-binding transcription activator 2
Alternative name(s):
Ethylene-induced calmodulin-binding protein c
Short name:
AtER66
Short name:
EICBP.c
Signal-responsive protein 4
Gene namesi
Name:CMTA2
Synonyms:SR4
Ordered Locus Names:At5g64220
ORF Names:MSJ1.6
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 5

Organism-specific databases

AraportiAT5G64220.
TAIRilocus:2173368. AT5G64220.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001144871 – 1050Calmodulin-binding transcription activator 2Add BLAST1050

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei984PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ6NPP4.
PRIDEiQ6NPP4.

PTM databases

iPTMnetiQ6NPP4.

Expressioni

Tissue specificityi

Expressed in roots, stems, old leaves, petals, sepals, top of carpels, stigmas, stamen filaments, anthers and siliques, but not in pollen.2 Publications

Inductioni

By salt, wounding, abscisic acid, H2O2 and salicylic acid.1 Publication

Gene expression databases

ExpressionAtlasiQ6NPP4. baseline and differential.
GenevisibleiQ6NPP4. AT.

Interactioni

Subunit structurei

Binds to calmodulin.

GO - Molecular functioni

Protein-protein interaction databases

STRINGi3702.AT5G64220.1.

Structurei

3D structure databases

ProteinModelPortaliQ6NPP4.
SMRiQ6NPP4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati661 – 690ANK 1Add BLAST30
Repeati694 – 723ANK 2Add BLAST30
Domaini870 – 899IQ 1PROSITE-ProRule annotationAdd BLAST30
Domaini893 – 922IQ 2PROSITE-ProRule annotationAdd BLAST30

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili957 – 985Sequence analysisAdd BLAST29

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi1011 – 1014Poly-Ser4

Sequence similaritiesi

Belongs to the CAMTA family.Curated

Keywords - Domaini

ANK repeat, Coiled coil, Repeat

Phylogenomic databases

eggNOGiKOG0520. Eukaryota.
ENOG410XS5M. LUCA.
HOGENOMiHOG000240102.
InParanoidiQ6NPP4.
KOiK21596.
OMAiCHAPPHE.
OrthoDBiEOG093600YW.
PhylomeDBiQ6NPP4.

Family and domain databases

CDDicd00204. ANK. 1 hit.
Gene3Di1.25.40.20. 1 hit.
2.60.40.10. 1 hit.
InterProiView protein in InterPro
IPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR005559. CG-1_dom.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR000048. IQ_motif_EF-hand-BS.
IPR027417. P-loop_NTPase.
PfamiView protein in Pfam
PF12796. Ank_2. 1 hit.
PF03859. CG-1. 1 hit.
PF00612. IQ. 2 hits.
SMARTiView protein in SMART
SM00248. ANK. 2 hits.
SM01076. CG-1. 1 hit.
SM00015. IQ. 2 hits.
SUPFAMiSSF48403. SSF48403. 1 hit.
SSF52540. SSF52540. 1 hit.
SSF81296. SSF81296. 1 hit.
PROSITEiView protein in PROSITE
PS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 2 hits.
PS51437. CG_1. 1 hit.
PS50096. IQ. 2 hits.

Sequencei

Sequence statusi: Complete.

Q6NPP4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADRGSFGFA PRLDIKQLLS EAQHRWLRPA EICEILRNHQ KFHIASEPPN
60 70 80 90 100
RPPSGSLFLF DRKVLRYFRK DGHNWRKKKD GKTVKEAHEK LKVGSIDVLH
110 120 130 140 150
CYYAHGEDNE NFQRRCYWML EQDLMHIVFV HYLEVKGNRM STSGTKENHS
160 170 180 190 200
NSLSGTGSVN VDSTATRSSI LSPLCEDADS GDSRQASSSL QQNPEPQTVV
210 220 230 240 250
PQIMHHQNAS TINSYNTTSV LGNRDGWTSA HGNRVKGSNS QRSGDVPAWD
260 270 280 290 300
ASFENSLARY QNLPYNAPLT QTQPSTFGLI PMEGKTEKGS LLTSEHLRNP
310 320 330 340 350
LQSQVNWQTP VQESVPLQKW PMDSHSGMTD ATDLALFGQG AHENFGTFSS
360 370 380 390 400
LLGSQDQQSS SFQAPFTNNE AAYIPKLGPE DLIYEASANQ TLPLRKALLK
410 420 430 440 450
KEDSLKKVDS FSRWVSKELG EMEDLQMQSS SGGIAWTSVE CENAAAGSSL
460 470 480 490 500
SPSLSEDQRF TMIDFWPKWT QTDSEVEVMV IGTFLLSPQE VTSYSWSCMF
510 520 530 540 550
GEVEVPADIL VDGVLCCHAP PHEVGRVPFY ITCSDRFSCS EVREFDFLPG
560 570 580 590 600
STRKLNATDI YGANTIETSL HLRFENLLAL RCSVQEHHIF ENVGEKRRKI
610 620 630 640 650
SKIMLLKDEK EPPLPGTIEK DLTELEAKER LIREEFEDKL YLWLIHKVTE
660 670 680 690 700
EGKGPNILDE DGQGVLHLAA ALGYDWAIKP ILAAGVSINF RDANGWSALH
710 720 730 740 750
WAAFSGREDT VAVLVSLGAD AGALADPSPE HPLGKTAADL AYGNGHRGIS
760 770 780 790 800
GFLAESSLTS YLEKLTVDAK ENSSADSSGA KAVLTVAERT ATPMSYGDVP
810 820 830 840 850
ETLSMKDSLT AVLNATQAAD RLHQVFRMQS FQRKQLSELG GDNKFDISDE
860 870 880 890 900
LAVSFAAAKT KKSGHSSGAV HAAAVQIQKK YRGWKKRKEF LLIRQRIVKI
910 920 930 940 950
QAHVRGHQVR KQYRAIIWSV GLLEKIILRW RRKGSGLRGF KRDTISKPTE
960 970 980 990 1000
PVCPAPQEDD YDFLKEGRKQ TEERLQKALT RVKSMAQYPE ARAQYRRLLT
1010 1020 1030 1040 1050
VVEGFRENEA SSSSALKNNT EEAANYNEED DLIDIDSLLD DDTFMSLAFE
Length:1,050
Mass (Da):117,258
Last modified:July 5, 2004 - v1
Checksum:i318050B641D646F9
GO

Sequence cautioni

The sequence BAB09853 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB008268 Genomic DNA. Translation: BAB09853.1. Sequence problems.
CP002688 Genomic DNA. Translation: AED97856.1.
CP002688 Genomic DNA. Translation: AED97857.1.
BT010874 mRNA. Translation: AAR24652.1.
RefSeqiNP_001032135.1. NM_001037058.2.
NP_201227.3. NM_125818.3.
UniGeneiAt.28963.
At.67020.

Genome annotation databases

EnsemblPlantsiAT5G64220.1; AT5G64220.1; AT5G64220.
AT5G64220.2; AT5G64220.2; AT5G64220.
GeneIDi836543.
GrameneiAT5G64220.1; AT5G64220.1; AT5G64220.
AT5G64220.2; AT5G64220.2; AT5G64220.
KEGGiath:AT5G64220.

Similar proteinsi

Entry informationi

Entry nameiCMTA2_ARATH
AccessioniPrimary (citable) accession number: Q6NPP4
Secondary accession number(s): Q9FMG3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 24, 2006
Last sequence update: July 5, 2004
Last modified: September 27, 2017
This is version 114 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families