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Q6NPF9 (TRXY1_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 80. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Thioredoxin Y1, chloroplastic
Short name=AtTrxy1
Gene names
Ordered Locus Names:At1g76760
ORF Names:F28O16.13
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length172 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Thiol-disulfide oxidoreductase that poorly activates chloroplastic malate dehydrogenase (NADP-MDH) and fructose-1,6-bisphosphatase. Provides reducing equivalents for peroxiredoxin Q. Ref.5

Subcellular location

Plastid › chloroplast stroma Ref.5 Ref.7.

Tissue specificity

Expressed in roots and seeds. Ref.5

Developmental stage

Expression increases in developing seeds and decreases during seed germination. Ref.5

Sequence similarities

Belongs to the thioredoxin family. Plant Y-type subfamily.

Contains 1 thioredoxin domain.

Sequence caution

The sequence AAF04439.1 differs from that shown. Reason: Erroneous gene model prediction.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Transit peptide1 – 6262Chloroplast Potential
Chain63 – 172110Thioredoxin Y1, chloroplastic
PRO_0000394539

Regions

Domain63 – 169107Thioredoxin

Sites

Active site931Nucleophile By similarity
Active site961Nucleophile By similarity
Site871Deprotonates C-terminal active site Cys By similarity
Site941Contributes to redox potential value By similarity
Site951Contributes to redox potential value By similarity

Amino acid modifications

Disulfide bond93 ↔ 96Redox-active By similarity

Sequences

Sequence LengthMass (Da)Tools
Q6NPF9 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: BD1F70B3838BB7DD

FASTA17219,250
        10         20         30         40         50         60 
MASISLSSST VPSLNSKESS GVSAFASRSI SAVKFQFPVR RVRTGDLKFP SLSSTTRCTP 

        70         80         90        100        110        120 
RRIEAKKQTF DSFEDLLVNS DKPVLVDYYA TWCGPCQFMV PILNEVSETL KDKIQVVKID 

       130        140        150        160        170 
TEKYPSIANK YKIEALPTFI LFKDGEPCDR FEGALTAKQL IQRIEDSLKV KP

« Hide

References

« Hide 'large scale' references
[1]"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. expand/collapse author list , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Arabidopsis cDNA clones."
Shinn P., Chen H., Cheuk R.F., Kim C.J., Ecker J.R.
Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[4]"Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs."
Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A., Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y., Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K. expand/collapse author list , Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y., Shinozaki K.
Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[5]"Characterization of plastidial thioredoxins from Arabidopsis belonging to the new y-type."
Collin V., Lamkemeyer P., Miginiac-Maslow M., Hirasawa M., Knaff D.B., Dietz K.J., Issakidis-Bourguet E.
Plant Physiol. 136:4088-4095(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE.
[6]"Comparative genomic study of the thioredoxin family in photosynthetic organisms with emphasis on Populus trichocarpa."
Chibani K., Wingsle G., Jacquot J.P., Gelhaye E., Rouhier N.
Mol. Plant 2:308-322(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY, NOMENCLATURE.
[7]"A novel extended family of stromal thioredoxins."
Cain P., Hall M., Schroder W.P., Kieselbach T., Robinson C.
Plant Mol. Biol. 70:273-281(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AC010718 Genomic DNA. Translation: AAF04439.1. Sequence problems.
CP002684 Genomic DNA. Translation: AEE35886.1.
BT010677 mRNA. Translation: AAR20734.1.
BT010965 mRNA. Translation: AAR24743.1.
AK227422 mRNA. Translation: BAE99426.1.
IPIIPI00542592.
PIRB96796.
RefSeqNP_177802.2. NM_106326.7.
UniGeneAt.34618.
At.72900.

3D structure databases

HSSPHSSP built from PDB template 1KEB based on UniProtKB P00274.
ProteinModelPortalQ6NPF9.
SMRQ6NPF9. Positions 67-169.
ModBaseSearch...

Protein-protein interaction databases

IntActQ6NPF9. 14 interactions.
STRING3702.AT1G76760.1-P.

Proteomic databases

PaxDbQ6NPF9.
PRIDEQ6NPF9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT1G76760.1; AT1G76760.1; AT1G76760.
GeneID844010.
KEGGath:AT1G76760.

Organism-specific databases

GeneFarm2477. 214.
TAIRAt1g76760.

Phylogenomic databases

eggNOGCOG0526.
HOGENOMHOG000292977.
InParanoidQ6NPF9.
OMADKIQVVK.
PhylomeDBQ6NPF9.
ProtClustDBCLSN2714796.

Gene expression databases

GenevestigatorQ6NPF9.

Family and domain databases

Gene3D3.40.30.10. 1 hit.
InterProIPR005746. Thioredoxin.
IPR012336. Thioredoxin-like_fold.
IPR017937. Thioredoxin_CS.
IPR013766. Thioredoxin_domain.
[Graphical view]
PANTHERPTHR10438. PTHR10438. 1 hit.
PfamPF00085. Thioredoxin. 1 hit.
[Graphical view]
PRINTSPR00421. THIOREDOXIN.
SUPFAMSSF52833. Thiordxn-like_fd. 1 hit.
TIGRFAMsTIGR01068. thioredoxin. 1 hit.
PROSITEPS00194. THIOREDOXIN_1. 1 hit.
PS51352. THIOREDOXIN_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameTRXY1_ARATH
AccessionPrimary (citable) accession number: Q6NPF9
Secondary accession number(s): Q9SRD7
Entry history
Integrated into UniProtKB/Swiss-Prot: June 15, 2010
Last sequence update: July 5, 2004
Last modified: May 1, 2013
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names

SIMILARITY comments

Index of protein domains and families

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