Q6NKY5 (Q6NKY5_ARATH) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Cysteine synthase RuleBase RU003985
EC=2.5.1.47 RuleBase RU003985

Gene names

Ordered Locus Names:	At1g55880 TAIR At1g55880
ORF Names:	AT1G55880 EMBL AEE33313.1

Organism

Arabidopsis thaliana (Mouse-ear cress) EMBL AAS99702.1

Taxonomic identifier

3702 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length	421 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	O(3)-acetyl-L-serine + H2S = L-cysteine + acetate. RuleBase RU003985
Sequence similarities	Belongs to the cysteine synthase/cystathionine beta-synthase family. RuleBase RU003985

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Cysteine biosynthesis RuleBase RU003985
Molecular function	Transferase RuleBase RU003985
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	cysteine biosynthetic process from serine Inferred from electronic annotation. Source: InterPro
Molecular function	cysteine synthase activity Inferred from electronic annotation. Source: EC pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro transferase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q6NKY5 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: C14B6C86A6138D85	FASTA	421	45,438
	10 20 30 40 50 60 MAPVNMTGAV VAAAALLMLT SYSFFFRLSE KKKRKEKLTM RNGLVDAIGN TPLIRINSLS 70 80 90 100 110 120 EATGCEILGK CEFLNPGGSV KDRVAVKIIQ EALESGKLFP GGIVTEGSAG STAISLATVA 130 140 150 160 170 180 PAYGCKCHVV IPDDAAIEKS QIIEALGASV ERVRPVSITH KDHYVNIARR RADEANELAS 190 200 210 220 230 240 KRRLGSETNG IHQEKTNGCT VEEVKEPSLF SDSVTGGFFA DQFENLANYR AHYEGTGPEI 250 260 270 280 290 300 WHQTQGNIDA FVAAAGTGGT LAGVSRFLQD KNERVKCFLI DPPGSGLYNK VTRGVMYTRE 310 320 330 340 350 360 EAEGRRLKNP FDTITEGIGI NRLTKNFLMA KLDGGFRGTD KEAVEMSRFL LKNDGLFVGS 370 380 390 400 410 420 SSAMNCVGAV RVAQTLGPGH TIVTILCDSG MRHLSKFHDP KYLNLYGLSP TAIGLEFLGI K

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana." Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W. Nature 408:816-820(2000) [PubMed: 11130712] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia.
[2]	The Arabidopsis Information Resource (TAIR) Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia.
[3]	"Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs." Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Morosawa T., Kamiya A., Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y., Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K. , Akiyama K., Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y., Shinozaki K. Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[4]	"Arabidopsis ORF clones." Kim C.J., Chen H., Cheuk R., Shinn P., Carninci P., Hayashizaki Y., Ishida J., Kamiya A., Kawai J., Narusaka M., Sakurai T., Satou M., Seki M., Shinozaki K., Ecker J.R. Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BT012558 mRNA. Translation: AAS99702.1. CP002684 Genomic DNA. Translation: AEE33313.1. AK226657 mRNA. Translation: BAE98765.1.
IPI	IPI00523834.
RefSeq	NP_175984.1. NM_104465.3.
UniGene	At.42875.
3D structure databases
HSSP	HSSP built from PDB template 1O58 based on UniProtKB Q9WZD3.
ProteinModelPortal	Q6NKY5.
SMR	Q6NKY5. Positions 43-398.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q6NKY5. 1 interaction.
STRING	Q6NKY5.
Proteomic databases
PRIDE	Q6NKY5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	AT1G55880.1; AT1G55880.1; AT1G55880.
GeneID	842038.
KEGG	ath:AT1G55880.
NMPDR	fig|3702.1.peg.5129.
Organism-specific databases
TAIR	At1g55880.
Phylogenomic databases
GeneTree	EPGT00050000010054.
InParanoid	Q6NKY5.
OMA	RVRPVSI.
PhylomeDB	Q6NKY5.
ProtClustDB	PLN02356.
Gene expression databases
Genevestigator	Q6NKY5.
Family and domain databases
InterPro	IPR001216. Cys_synth_BS. IPR001926. PyrdxlP-dep_enz_bsu. [Graphical view]
KO	K01738.
Pfam	PF00291. PALP. 1 hit. [Graphical view]
SUPFAM	SSF53686. PyrdxlP-dep_enz_bsu. 1 hit.
PROSITE	PS00901. CYS_SYNTHASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q6NKY5_ARATH

Accession

Primary (citable) accession number: Q6NKY5

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	January 25, 2012
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)