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Q6NK15

- Q6NK15_CORDI

UniProt

Q6NK15 - Q6NK15_CORDI

Protein
Submitted name:

Diphtheria toxin

Gene

tox

Organism
Corynebacterium diphtheriae (strain ATCC 700971 / NCTC 13129 / Biotype gravis)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 56 (01 Oct 2014)
      Sequence version 1 (05 Jul 2004)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. identical protein binding Source: IntAct
    2. NAD+-diphthamide ADP-ribosyltransferase activity Source: UniProtKB-EC

    GO - Biological processi

    1. pathogenesis Source: InterPro

    Keywords - Molecular functioni

    GlycosyltransferaseImported, Transferase

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Diphtheria toxinImported (EC:2.4.2.36Imported)
    Gene namesi
    Name:toxImported
    Ordered Locus Names:DIP0222Imported
    OrganismiCorynebacterium diphtheriae (strain ATCC 700971 / NCTC 13129 / Biotype gravis)Imported
    Taxonomic identifieri257309 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeCorynebacteriaceaeCorynebacterium
    ProteomesiUP000002198: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. extracellular region Source: InterPro

    Interactioni

    Binary interactionsi

    WithEntry#Exp.IntActNotes
    itself2EBI-7700183,EBI-7700183

    Protein-protein interaction databases

    MINTiMINT-7298372.
    STRINGi257309.DIP0222.

    Structurei

    3D structure databases

    ProteinModelPortaliQ6NK15.
    SMRiQ6NK15. Positions 26-560.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    KOiK00776.

    Family and domain databases

    Gene3Di1.10.490.40. 1 hit.
    2.60.40.700. 1 hit.
    InterProiIPR000512. Diphtheria_toxin.
    IPR022406. Diphtheria_toxin_catalytic_dom.
    IPR022404. Diphtheria_toxin_rcpt-bd_dom.
    IPR022405. Diphtheria_toxin_translocation.
    [Graphical view]
    PfamiPF02763. Diphtheria_C. 1 hit.
    PF01324. Diphtheria_R. 1 hit.
    PF02764. Diphtheria_T. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000490. Diphtheria_toxin. 1 hit.
    PRINTSiPR00769. DPTHRIATOXIN.
    SUPFAMiSSF49380. SSF49380. 1 hit.
    SSF56845. SSF56845. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q6NK15-1 [UniParc]FASTAAdd to Basket

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    MSRKLFASIL IGALLGIGAP PSAHAGADDV VDSSKSFVME NFSSYHGTKP    50
    GYVDSIQKGI QKPKSGTQGN YDDDWKGFYS TDNKYDAAGY SVDNENPLSG 100
    KAGGVVKVTY PGLTKVLALK VDNAETIKKE LGLSLTEPLM EQVGTEEFIK 150
    RFGDGASRVV LSLPFAEGSS SVEYINNWEQ AKALSVELEI NFETRGKRGQ 200
    DAMYEYMAQA CAGNRVRRSV GSSLSCINLD WDVIRDKTKT KIESLKEHGP 250
    IKNKMSESPN KTVSEEKAKQ YLEEFHQTAL EHPELSELKT VTGTNPVFAG 300
    ANYAAWAVNV AQVIDSETAD NLEKTTAALS ILPGIGSVMG IADGAVHHNT 350
    EEIVAQSIAL SSLMVAQAIP LVGELVDIGF AAYNFVESII NLFQVVHNSY 400
    NRPAYSPGHK TQPFLHDGYA VSWNTVEDSI IRTGFQGESG HDIKITAENT 450
    PLPIAGVLLP TIPGKLDVNK SKTHISVNGR KIRMRCRAID GDVTFCRPKS 500
    PVYVGNGVHA NLHVAFHRSS SEKIHSNEIS SDSIGVLGYQ KTVDHTKVNS 550
    KLSLFFEIKS 560
    Length:560
    Mass (Da):60,815
    Last modified:July 5, 2004 - v1
    Checksum:i51F5718361B94EAB
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BX248354 Genomic DNA. Translation: CAE48728.1.
    RefSeqiNP_938615.1. NC_002935.2.
    WP_003850266.1. NC_002935.2.

    Genome annotation databases

    EnsemblBacteriaiCAE48728; CAE48728; DIP0222.
    GeneIDi2650491.
    KEGGicdi:DIP0222.
    PATRICi21481599. VBICorDip47633_0209.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BX248354 Genomic DNA. Translation: CAE48728.1 .
    RefSeqi NP_938615.1. NC_002935.2.
    WP_003850266.1. NC_002935.2.

    3D structure databases

    ProteinModelPortali Q6NK15.
    SMRi Q6NK15. Positions 26-560.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    MINTi MINT-7298372.
    STRINGi 257309.DIP0222.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAE48728 ; CAE48728 ; DIP0222 .
    GeneIDi 2650491.
    KEGGi cdi:DIP0222.
    PATRICi 21481599. VBICorDip47633_0209.

    Phylogenomic databases

    KOi K00776.

    Family and domain databases

    Gene3Di 1.10.490.40. 1 hit.
    2.60.40.700. 1 hit.
    InterProi IPR000512. Diphtheria_toxin.
    IPR022406. Diphtheria_toxin_catalytic_dom.
    IPR022404. Diphtheria_toxin_rcpt-bd_dom.
    IPR022405. Diphtheria_toxin_translocation.
    [Graphical view ]
    Pfami PF02763. Diphtheria_C. 1 hit.
    PF01324. Diphtheria_R. 1 hit.
    PF02764. Diphtheria_T. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000490. Diphtheria_toxin. 1 hit.
    PRINTSi PR00769. DPTHRIATOXIN.
    SUPFAMi SSF49380. SSF49380. 1 hit.
    SSF56845. SSF56845. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 700971 / NCTC 13129 / Biotype gravisImported.

    Entry informationi

    Entry nameiQ6NK15_CORDI
    AccessioniPrimary (citable) accession number: Q6NK15
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 5, 2004
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 56 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3